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Items: 1 to 20 of 102

1.

Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms: A Randomized Clinical Trial.

Mitchell CM, Reed SD, Diem S, Larson JC, Newton KM, Ensrud KE, LaCroix AZ, Caan B, Guthrie KA.

JAMA Intern Med. 2018 May 1;178(5):681-690. doi: 10.1001/jamainternmed.2018.0116.

2.

Sexual frequency and pain in a randomized clinical trial of vaginal estradiol tablets, moisturizer, and placebo in postmenopausal women.

Mitchell CM, Guthrie KA, Larson J, Diem S, LaCroix AZ, Caan B, Shifren JL, Woods NF, Heiman JR, Lindau ST, Reed SD.

Menopause. 2019 Apr 15. doi: 10.1097/GME.0000000000001341. [Epub ahead of print]

PMID:
30994576
3.

Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial.

Diem SJ, Guthrie KA, Mitchell CM, Reed SD, Larson JC, Ensrud KE, LaCroix AZ.

Menopause. 2018 Oct;25(10):1086-1093. doi: 10.1097/GME.0000000000001131.

4.

A Randomized, Multicenter, Double-Blind, Study to Evaluate the Safety and Efficacy of Estradiol Vaginal Cream 0.003% in Postmenopausal Women with Vaginal Dryness as the Most Bothersome Symptom.

Archer DF, Kimble TD, Lin FDY, Battucci S, Sniukiene V, Liu JH.

J Womens Health (Larchmt). 2018 Mar;27(3):231-237. doi: 10.1089/jwh.2017.6515. Epub 2017 Dec 1.

5.
7.

TX-004HR Improves Sexual Function as Measured by the Female Sexual Function Index in Postmenopausal Women With Vulvar and Vaginal Atrophy: The REJOICE Trial.

Kingsberg SA, Derogatis L, Simon JA, Constantine GD, Graham S, Bernick B, Gasper G, Mirkin S.

J Sex Med. 2016 Dec;13(12):1930-1937. doi: 10.1016/j.jsxm.2016.09.002. Epub 2016 Sep 28.

8.

Microdose transdermal estrogen therapy for relief of vulvovaginal symptoms in postmenopausal women.

Bachmann GA, Schaefers M, Uddin A, Utian WH.

Menopause. 2009 Sep-Oct;16(5):877-82. doi: 10.1097/gme.0b013e3181a15606.

PMID:
19458560
9.

Efficacy and safety of ospemifene in postmenopausal women with moderate-to-severe vaginal dryness: a phase 3, randomized, double-blind, placebo-controlled, multicenter trial.

Archer DF, Goldstein SR, Simon JA, Waldbaum AS, Sussman SA, Altomare C, Zhu J, Yoshida Y, Schaffer S, Soulban G.

Menopause. 2019 Jan 28. doi: 10.1097/GME.0000000000001292. [Epub ahead of print]

PMID:
30694917
10.

Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS).

Taylor HS, Tal A, Pal L, Li F, Black DM, Brinton EA, Budoff MJ, Cedars MI, Du W, Hodis HN, Lobo RA, Manson JE, Merriam GR, Miller VM, Naftolin F, Neal-Perry G, Santoro NF, Harman SM.

JAMA Intern Med. 2017 Oct 1;177(10):1471-1479. doi: 10.1001/jamainternmed.2017.3877.

11.

Low dose of transdermal estradiol gel for treatment of symptomatic postmenopausal women: a randomized controlled trial.

Simon JA, Bouchard C, Waldbaum A, Utian W, Zborowski J, Snabes MC.

Obstet Gynecol. 2007 Mar;109(3):588-96.

PMID:
17329509
12.

Efficacy and safety of a non-hormonal intravaginal moisturizer for the treatment of vaginal dryness in postmenopausal women with sexual dysfunction.

Vale F, Rezende C, Raciclan A, Bretas T, Geber S.

Eur J Obstet Gynecol Reprod Biol. 2019 Mar;234:92-95. doi: 10.1016/j.ejogrb.2018.12.040. Epub 2019 Jan 11.

PMID:
30677618
13.

Twice-weekly synthetic conjugated estrogens vaginal cream for the treatment of vaginal atrophy.

Freedman M, Kaunitz AM, Reape KZ, Hait H, Shu H.

Menopause. 2009 Jul-Aug;16(4):735-41. doi: 10.1097/gme.0b013e318199e734.

PMID:
19252451
14.

Local oestrogen for vaginal atrophy in postmenopausal women.

Lethaby A, Ayeleke RO, Roberts H.

Cochrane Database Syst Rev. 2016 Aug 31;(8):CD001500. doi: 10.1002/14651858.CD001500.pub3. Review.

PMID:
27577677
15.

The REJOICE trial: a phase 3 randomized, controlled trial evaluating the safety and efficacy of a novel vaginal estradiol soft-gel capsule for symptomatic vulvar and vaginal atrophy.

Constantine GD, Simon JA, Pickar JH, Archer DF, Kushner H, Bernick B, Gasper G, Graham S, Mirkin S; REJOICE Study Group.

Menopause. 2017 Apr;24(4):409-416. doi: 10.1097/GME.0000000000000786.

16.

Effective treatment of vaginal atrophy with an ultra-low-dose estradiol vaginal tablet.

Simon J, Nachtigall L, Gut R, Lang E, Archer DF, Utian W.

Obstet Gynecol. 2008 Nov;112(5):1053-60. doi: 10.1097/AOG.0b013e31818aa7c3. Erratum in: Obstet Gynecol. 2008 Dec;112(6):1392.

PMID:
18978105
17.

Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness, symptoms of vulvovaginal atrophy, and of the genitourinary syndrome of menopause.

Labrie F, Archer DF, Koltun W, Vachon A, Young D, Frenette L, Portman D, Montesino M, Côté I, Parent J, Lavoie L, Beauregard A, Martel C, Vaillancourt M, Balser J, Moyneur É; VVA Prasterone Research Group.

Menopause. 2016 Mar;23(3):243-56. doi: 10.1097/GME.0000000000000571.

PMID:
26731686
18.

Decreased efficacy of twice-weekly intravaginal dehydroepiandrosterone on vulvovaginal atrophy.

Bouchard C, Labrie F, Archer DF, Portman DJ, Koltun W, Elfassi É, Grainger DA, Ayotte N, Cooper TA, Martens M, Waldbaum AS, Labrie C, Côté I, Lavoie L, Martel C, Balser J; VVA Prasterone Group.

Climacteric. 2015;18(4):590-607. doi: 10.3109/13697137.2014.992012. Epub 2015 Mar 3.

PMID:
25511551
19.

Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness, symptoms of vulvovaginal atrophy, and of the genitourinary syndrome of menopause.

Labrie F, Archer DF, Koltun W, Vachon A, Young D, Frenette L, Portman D, Montesino M, Côté I, Parent J, Lavoie L, BSc AB, Martel C, Vaillancourt M, Balser J, Moyneur É; members of the VVA Prasterone Research Group.

Menopause. 2018 Nov;25(11):1339-1353. doi: 10.1097/GME.0000000000001238.

PMID:
30358731
20.

Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine for vasomotor symptoms: a randomized clinical trial.

Joffe H, Guthrie KA, LaCroix AZ, Reed SD, Ensrud KE, Manson JE, Newton KM, Freeman EW, Anderson GL, Larson JC, Hunt J, Shifren J, Rexrode KM, Caan B, Sternfeld B, Carpenter JS, Cohen L.

JAMA Intern Med. 2014 Jul;174(7):1058-66. doi: 10.1001/jamainternmed.2014.1891.

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