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Items: 1 to 20 of 103

1.
2.

Transcription factor Lhx2 is necessary and sufficient to suppress astrogliogenesis and promote neurogenesis in the developing hippocampus.

Subramanian L, Sarkar A, Shetty AS, Muralidharan B, Padmanabhan H, Piper M, Monuki ES, Bach I, Gronostajski RM, Richards LJ, Tole S.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):E265-74. doi: 10.1073/pnas.1101109108. Epub 2011 Jun 20.

3.

Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron-Glia Cell-Fate Switch in the Developing Hippocampus.

Muralidharan B, Keruzore M, Pradhan SJ, Roy B, Shetty AS, Kinare V, D'Souza L, Maheshwari U, Karmodiya K, Suresh A, Galande S, Bellefroid EJ, Tole S.

J Neurosci. 2017 Nov 15;37(46):11245-11254. doi: 10.1523/JNEUROSCI.1535-17.2017. Epub 2017 Oct 12.

4.

Reprogramming fibroblasts to neural-precursor-like cells by structured overexpression of pallial patterning genes.

Raciti M, Granzotto M, Duc MD, Fimiani C, Cellot G, Cherubini E, Mallamaci A.

Mol Cell Neurosci. 2013 Nov;57:42-53. doi: 10.1016/j.mcn.2013.10.004. Epub 2013 Oct 12.

PMID:
24128663
5.

LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1.

Hou PS, Chuang CY, Kao CF, Chou SJ, Stone L, Ho HN, Chien CL, Kuo HC.

Nucleic Acids Res. 2013 Sep;41(16):7753-70. doi: 10.1093/nar/gkt567. Epub 2013 Jun 26.

6.

Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis.

de Melo J, Clark BS, Blackshaw S.

Sci Rep. 2016 Sep 8;6:32757. doi: 10.1038/srep32757.

7.
8.

Novel functions of LHX2 and PAX6 in the developing telencephalon revealed upon combined loss of both genes.

Godbole G, Roy A, Shetty AS, Tole S.

Neural Dev. 2017 Nov 15;12(1):19. doi: 10.1186/s13064-017-0097-y.

9.

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

Roy A, de Melo J, Chaturvedi D, Thein T, Cabrera-Socorro A, Houart C, Meyer G, Blackshaw S, Tole S.

J Neurosci. 2013 Apr 17;33(16):6877-84. doi: 10.1523/JNEUROSCI.4216-12.2013.

10.

Role for Lhx2 in corticogenesis through regulation of progenitor differentiation.

Chou SJ, O'Leary DD.

Mol Cell Neurosci. 2013 Sep;56:1-9. doi: 10.1016/j.mcn.2013.02.006. Epub 2013 Feb 26.

11.

A Novel and Multivalent Role of Pax6 in Cerebellar Development.

Yeung J, Ha TJ, Swanson DJ, Goldowitz D.

J Neurosci. 2016 Aug 31;36(35):9057-69. doi: 10.1523/JNEUROSCI.4385-15.2016.

12.

Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina.

Gordon PJ, Yun S, Clark AM, Monuki ES, Murtaugh LC, Levine EM.

J Neurosci. 2013 Jul 24;33(30):12197-207. doi: 10.1523/JNEUROSCI.1494-13.2013.

13.

The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation.

Tétreault N, Champagne MP, Bernier G.

Dev Biol. 2009 Mar 15;327(2):541-50. doi: 10.1016/j.ydbio.2008.12.022. Epub 2008 Dec 30.

14.

Neurogenic differentiation by hippocampal neural stem and progenitor cells is biased by NFIX expression.

Harris L, Zalucki O, Clément O, Fraser J, Matuzelski E, Oishi S, Harvey TJ, Burne THJ, Heng JI, Gronostajski RM, Piper M.

Development. 2018 Feb 7;145(3). pii: dev155689. doi: 10.1242/dev.155689.

15.

Ldb1- and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in the retina.

de Melo J, Clark BS, Venkataraman A, Shiau F, Zibetti C, Blackshaw S.

Development. 2018 Apr 30;145(9). pii: dev159970. doi: 10.1242/dev.159970.

16.

LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx2.

Kodaka Y, Tanaka K, Kitajima K, Tanegashima K, Matsuda R, Hara T.

Exp Cell Res. 2015 Feb 15;331(2):309-19. doi: 10.1016/j.yexcr.2014.11.009. Epub 2014 Nov 24.

PMID:
25460335
17.

The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors.

Marcos-Mondéjar P, Peregrín S, Li JY, Carlsson L, Tole S, López-Bendito G.

J Neurosci. 2012 Mar 28;32(13):4372-85. doi: 10.1523/JNEUROSCI.5851-11.2012.

18.

Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells.

Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ.

Stem Cells. 2014 Jan;32(1):45-58. doi: 10.1002/stem.1561.

19.

NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells.

Tchieu J, Calder EL, Guttikonda SR, Gutzwiller EM, Aromolaran KA, Steinbeck JA, Goldstein PA, Studer L.

Nat Biotechnol. 2019 Mar;37(3):267-275. doi: 10.1038/s41587-019-0035-0. Epub 2019 Feb 25.

PMID:
30804533
20.

Expression of LIM-homeodomain transcription factors in the developing and mature mouse retina.

Balasubramanian R, Bui A, Ding Q, Gan L.

Gene Expr Patterns. 2014 Jan;14(1):1-8. doi: 10.1016/j.gep.2013.12.001. Epub 2013 Dec 10.

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