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Items: 1 to 20 of 97

1.

Leptin Replacement Reestablishes Brain Insulin Action in the Hypothalamus in Congenital Leptin Deficiency.

Frank-Podlech S, von Schnurbein J, Veit R, Heni M, Machann J, Heinze JM, Kullmann S, Manzoor J, Mahmood S, Häring HU, Preissl H, Wabitsch M, Fritsche A.

Diabetes Care. 2018 Apr;41(4):907-910. doi: 10.2337/dc17-1867. Epub 2018 Jan 24.

PMID:
29367426
2.

Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin-sensitive subjects without altering brain structure.

Farr OM, Fiorenza C, Papageorgiou P, Brinkoetter M, Ziemke F, Koo BB, Rojas R, Mantzoros CS.

J Clin Endocrinol Metab. 2014 Dec;99(12):E2529-38. doi: 10.1210/jc.2014-2774.

3.

The Effects of Leptin Replacement on Neural Plasticity.

Paz-Filho GJ.

Neural Plast. 2016;2016:8528934. doi: 10.1155/2016/8528934. Epub 2016 Jan 3. Review.

4.

Long-term stabilization effects of leptin on brain functions in a leptin-deficient patient.

Frank S, Heni M, Moss A, von Schnurbein J, Farooqi S, Häring HU, Fritsche A, Preissl H, Wabitsch M.

PLoS One. 2013 Jun 14;8(6):e65893. doi: 10.1371/journal.pone.0065893. Print 2013.

5.

Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy.

Paz-Filho G, Mastronardi C, Delibasi T, Wong ML, Licinio J.

Arq Bras Endocrinol Metabol. 2010 Nov;54(8):690-7.

6.

Rethinking leptin and insulin action: therapeutic opportunities for diabetes.

Yildiz BO, Haznedaroglu IC.

Int J Biochem Cell Biol. 2006;38(5-6):820-30. Epub 2005 Oct 3. Review.

PMID:
16236542
7.

Comparison of efficacy and safety of leptin replacement therapy in moderately and severely hypoleptinemic patients with familial partial lipodystrophy of the Dunnigan variety.

Simha V, Subramanyam L, Szczepaniak L, Quittner C, Adams-Huet B, Snell P, Garg A.

J Clin Endocrinol Metab. 2012 Mar;97(3):785-92. doi: 10.1210/jc.2011-2229. Epub 2011 Dec 14.

8.

Bone mineral content in patients with congenital generalized lipodystrophy is unaffected by metreleptin replacement therapy.

Christensen JD, Lungu AO, Cochran E, Collins MT, Gafni RI, Reynolds JC, Rother KI, Gorden P, Brown RJ.

J Clin Endocrinol Metab. 2014 Aug;99(8):E1493-500. doi: 10.1210/jc.2014-1353. Epub 2014 Jul 29.

9.

Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients.

Paz-Filho G, Esposito K, Hurwitz B, Sharma A, Dong C, Andreev V, Delibasi T, Erol H, Ayala A, Wong ML, Licinio J.

Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1401-8. doi: 10.1152/ajpendo.90450.2008. Epub 2008 Oct 14.

10.

Leptin replacement prevents weight loss-induced metabolic adaptation in congenital leptin-deficient patients.

Galgani JE, Greenway FL, Caglayan S, Wong ML, Licinio J, Ravussin E.

J Clin Endocrinol Metab. 2010 Feb;95(2):851-5. doi: 10.1210/jc.2009-1739. Epub 2010 Jan 8.

11.

Leptin treatment: facts and expectations.

Paz-Filho G, Mastronardi CA, Licinio J.

Metabolism. 2015 Jan;64(1):146-56. doi: 10.1016/j.metabol.2014.07.014. Epub 2014 Aug 3. Review.

12.
13.

Rationale for leptin-replacement therapy for severe lipodystrophy.

Oral EA, Chan JL.

Endocr Pract. 2010 Mar-Apr;16(2):324-33. doi: 10.4158/EP09155.RA. Review.

PMID:
20061299
14.

Rapid improvement of hepatic steatosis after initiation of leptin substitution in a leptin-deficient girl.

von Schnurbein J, Heni M, Moss A, Nagel SA, Machann J, Muehleder H, Debatin KM, Farooqi S, Wabitsch M.

Horm Res Paediatr. 2013;79(5):310-7. doi: 10.1159/000348541. Epub 2013 May 7.

PMID:
23651953
15.

Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults.

Kullmann S, Heni M, Veit R, Scheffler K, Machann J, Häring HU, Fritsche A, Preissl H.

Diabetes Care. 2015 Jun;38(6):1044-50. doi: 10.2337/dc14-2319. Epub 2015 Mar 20.

PMID:
25795413
16.

Adipose tissue transplantation protects ob/ob mice from obesity, normalizes insulin sensitivity and restores fertility.

Klebanov S, Astle CM, DeSimone O, Ablamunits V, Harrison DE.

J Endocrinol. 2005 Jul;186(1):203-11.

PMID:
16002549
17.

Exercise enhances insulin and leptin signaling in the cerebral cortex and hypothalamus during dexamethasone-induced stress in diabetic rats.

Park S, Jang JS, Jun DW, Hong SM.

Neuroendocrinology. 2005;82(5-6):282-93. Epub 2006 May 4.

PMID:
16721034
18.

Leptin and insulin resistance: good, bad, or still unclear?

Oral EA, Burant C.

Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E394-5, author reply E396. doi: 10.1152/ajpendo.90914.2008. No abstract available.

19.

Relationship of adipokine to insulin sensitivity and glycemic regulation in obese women--the effect of body weight reduction by caloric restriction.

Golubović MV, Dimić D, Antić S, Radenković S, Djindjić B, Jovanović M.

Vojnosanit Pregl. 2013 Mar;70(3):284-91.

PMID:
23607240
20.

Preadipocyte factor-1 levels are higher in women with hypothalamic amenorrhea and are associated with bone mineral content and bone mineral density through a mechanism independent of leptin.

Aronis KN, Kilim H, Chamberland JP, Breggia A, Rosen C, Mantzoros CS.

J Clin Endocrinol Metab. 2011 Oct;96(10):E1634-9. doi: 10.1210/jc.2011-0600. Epub 2011 Jul 27.

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