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Items: 1 to 20 of 104

1.

Perturbed bone composition and integrity with disorganized osteoblast function in zinc receptor/Gpr39-deficient mice.

Jovanovic M, Schmidt FN, Guterman-Ram G, Khayyeri H, Hiram-Bab S, Orenbuch A, Katchkovsky S, Aflalo A, Isaksson H, Busse B, Jähn K, Levaot N.

FASEB J. 2018 May;32(5):2507-2518. doi: 10.1096/fj.201700661RR. Epub 2018 Jan 2.

PMID:
29295862
2.

Osteoclast deficiency results in disorganized matrix, reduced mineralization, and abnormal osteoblast behavior in developing bone.

Dai XM, Zong XH, Akhter MP, Stanley ER.

J Bone Miner Res. 2004 Sep;19(9):1441-51. Epub 2004 Jun 2.

3.
4.

Zinc sensing receptor signaling, mediated by GPR39, reduces butyrate-induced cell death in HT29 colonocytes via upregulation of clusterin.

Cohen L, Azriel-Tamir H, Arotsker N, Sekler I, Hershfinkel M.

PLoS One. 2012;7(4):e35482. doi: 10.1371/journal.pone.0035482. Epub 2012 Apr 24.

5.

The Zinc Sensing Receptor, ZnR/GPR39, in Health and Disease.

Hershfinkel M.

Int J Mol Sci. 2018 Feb 1;19(2). pii: E439. doi: 10.3390/ijms19020439. Review.

6.

The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl- absorption, via basolateral KCC1, and reduces fluid loss.

Sunuwar L, Asraf H, Donowitz M, Sekler I, Hershfinkel M.

Biochim Biophys Acta Mol Basis Dis. 2017 Apr;1863(4):947-960. doi: 10.1016/j.bbadis.2017.01.009. Epub 2017 Jan 16.

7.

The ZnR/GPR39 interacts with the CaSR to enhance signaling in prostate and salivary epithelia.

Asraf H, Salomon S, Nevo A, Sekler I, Mayer D, Hershfinkel M.

J Cell Physiol. 2014 Jul;229(7):868-77. doi: 10.1002/jcp.24514.

PMID:
24264723
8.
9.

Circulating fibronectin affects bone matrix, whereas osteoblast fibronectin modulates osteoblast function.

Bentmann A, Kawelke N, Moss D, Zentgraf H, Bala Y, Berger I, Gasser JA, Nakchbandi IA.

J Bone Miner Res. 2010 Apr;25(4):706-15. doi: 10.1359/jbmr.091011.

10.

Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance.

Tang SY, Herber RP, Ho SP, Alliston T.

J Bone Miner Res. 2012 Sep;27(9):1936-50. doi: 10.1002/jbmr.1646.

11.

Zinc regulates vascular endothelial cell activity through zinc-sensing receptor ZnR/GPR39.

Zhu D, Su Y, Zheng Y, Fu B, Tang L, Qin YX.

Am J Physiol Cell Physiol. 2018 Apr 1;314(4):C404-C414. doi: 10.1152/ajpcell.00279.2017. Epub 2017 Dec 13.

12.

The zinc sensing receptor, ZnR/GPR39, in health and disease.

Sunuwar L, Gilad D, Hershfinkel M.

Front Biosci (Landmark Ed). 2017 Mar 1;22:1469-1492. Review.

PMID:
28199213
13.

Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth.

Mosig RA, Dowling O, DiFeo A, Ramirez MC, Parker IC, Abe E, Diouri J, Aqeel AA, Wylie JD, Oblander SA, Madri J, Bianco P, Apte SS, Zaidi M, Doty SB, Majeska RJ, Schaffler MB, Martignetti JA.

Hum Mol Genet. 2007 May 1;16(9):1113-23. Epub 2007 Mar 30.

14.

Extracellular pH regulates zinc signaling via an Asp residue of the zinc-sensing receptor (ZnR/GPR39).

Cohen L, Asraf H, Sekler I, Hershfinkel M.

J Biol Chem. 2012 Sep 28;287(40):33339-50. Epub 2012 Aug 9.

15.

Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor.

Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC.

Calcif Tissue Int. 2011 Jul;89(1):10-20. doi: 10.1007/s00223-011-9487-z. Epub 2011 Apr 28.

16.

The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victims.

Młyniec K, Doboszewska U, Szewczyk B, Sowa-Kućma M, Misztak P, Piekoszewski W, Trela F, Ostachowicz B, Nowak G.

Neuropharmacology. 2014 Apr;79:290-7. doi: 10.1016/j.neuropharm.2013.12.001. Epub 2013 Dec 10.

PMID:
24333148
17.

GPR39 (zinc receptor) knockout mice exhibit depression-like behavior and CREB/BDNF down-regulation in the hippocampus.

Młyniec K, Budziszewska B, Holst B, Ostachowicz B, Nowak G.

Int J Neuropsychopharmacol. 2014 Oct 31;18(3). pii: pyu002. doi: 10.1093/ijnp/pyu002.

18.

Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix properties.

Wang CJ, Chen IP, Koczon-Jaremko B, Boskey AL, Ueki Y, Kuhn L, Reichenberger EJ.

Bone. 2010 May;46(5):1306-15. doi: 10.1016/j.bone.2010.01.380. Epub 2010 Feb 1.

19.

Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.

Mohammad KS, Chen CG, Balooch G, Stebbins E, McKenna CR, Davis H, Niewolna M, Peng XH, Nguyen DH, Ionova-Martin SS, Bracey JW, Hogue WR, Wong DH, Ritchie RO, Suva LJ, Derynck R, Guise TA, Alliston T.

PLoS One. 2009;4(4):e5275. doi: 10.1371/journal.pone.0005275. Epub 2008 Apr 16.

20.

Osteoblast extracellular Ca2+ -sensing receptor regulates bone development, mineralization, and turnover.

Dvorak-Ewell MM, Chen TH, Liang N, Garvey C, Liu B, Tu C, Chang W, Bikle DD, Shoback DM.

J Bone Miner Res. 2011 Dec;26(12):2935-47. doi: 10.1002/jbmr.520.

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