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Items: 1 to 20 of 87

1.

Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic.

Arras SDM, Ormerod KL, Erpf PE, Espinosa MI, Carpenter AC, Blundell RD, Stowasser SR, Schulz BL, Tanurdzic M, Fraser JA.

Sci Rep. 2017 Dec 20;7(1):17918. doi: 10.1038/s41598-017-18106-2.

2.

A unique chromosomal rearrangement in the Cryptococcus neoformans var. grubii type strain enhances key phenotypes associated with virulence.

Morrow CA, Lee IR, Chow EW, Ormerod KL, Goldinger A, Byrnes EJ 3rd, Nielsen K, Heitman J, Schirra HJ, Fraser JA.

MBio. 2012 Feb 28;3(2). pii: e00310-11. doi: 10.1128/mBio.00310-11. Print 2012.

3.

Microevolution of a standard strain of Cryptococcus neoformans resulting in differences in virulence and other phenotypes.

Franzot SP, Mukherjee J, Cherniak R, Chen LC, Hamdan JS, Casadevall A.

Infect Immun. 1998 Jan;66(1):89-97.

4.

Microevolution during serial mouse passage demonstrates FRE3 as a virulence adaptation gene in Cryptococcus neoformans.

Hu G, Chen SH, Qiu J, Bennett JE, Myers TG, Williamson PR.

MBio. 2014 Apr 1;5(2):e00941-14. doi: 10.1128/mBio.00941-14.

5.

Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease.

Vu K, Tham R, Uhrig JP, Thompson GR 3rd, Na Pombejra S, Jamklang M, Bautos JM, Gelli A.

MBio. 2014 Jun 3;5(3):e01101-14. doi: 10.1128/mBio.01101-14.

6.

Toward an integrated model of capsule regulation in Cryptococcus neoformans.

Haynes BC, Skowyra ML, Spencer SJ, Gish SR, Williams M, Held EP, Brent MR, Doering TL.

PLoS Pathog. 2011 Dec;7(12):e1002411. doi: 10.1371/journal.ppat.1002411. Epub 2011 Dec 8.

7.

Identification of a novel gene, URE2, that functionally complements a urease-negative clinical strain of Cryptococcus neoformans.

Varma A, Wu S, Guo N, Liao W, Lu G, Li A, Hu Y, Bulmer G, Kwon-Chung KJ.

Microbiology. 2006 Dec;152(Pt 12):3723-31.

PMID:
17159224
8.

Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.

Janbon G, Ormerod KL, Paulet D, Byrnes EJ 3rd, Yadav V, Chatterjee G, Mullapudi N, Hon CC, Billmyre RB, Brunel F, Bahn YS, Chen W, Chen Y, Chow EW, Coppée JY, Floyd-Averette A, Gaillardin C, Gerik KJ, Goldberg J, Gonzalez-Hilarion S, Gujja S, Hamlin JL, Hsueh YP, Ianiri G, Jones S, Kodira CD, Kozubowski L, Lam W, Marra M, Mesner LD, Mieczkowski PA, Moyrand F, Nielsen K, Proux C, Rossignol T, Schein JE, Sun S, Wollschlaeger C, Wood IA, Zeng Q, Neuvéglise C, Newlon CS, Perfect JR, Lodge JK, Idnurm A, Stajich JE, Kronstad JW, Sanyal K, Heitman J, Fraser JA, Cuomo CA, Dietrich FS.

PLoS Genet. 2014 Apr 17;10(4):e1004261. doi: 10.1371/journal.pgen.1004261. eCollection 2014 Apr.

9.

Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis.

Feretzaki M, Hardison SE, Wormley FL Jr, Heitman J.

PLoS One. 2014 Aug 5;9(8):e104432. doi: 10.1371/journal.pone.0104432. eCollection 2014.

10.

DNA mutations mediate microevolution between host-adapted forms of the pathogenic fungus Cryptococcus neoformans.

Magditch DA, Liu TB, Xue C, Idnurm A.

PLoS Pathog. 2012;8(10):e1002936. doi: 10.1371/journal.ppat.1002936. Epub 2012 Oct 4.

11.

Identification of Aph1, a phosphate-regulated, secreted, and vacuolar acid phosphatase in Cryptococcus neoformans.

Lev S, Crossett B, Cha SY, Desmarini D, Li C, Chayakulkeeree M, Wilson CF, Williamson PR, Sorrell TC, Djordjevic JT.

MBio. 2014 Sep 16;5(5):e01649-14. doi: 10.1128/mBio.01649-14.

12.

Microevolution of Cryptococcus neoformans driven by massive tandem gene amplification.

Chow EW, Morrow CA, Djordjevic JT, Wood IA, Fraser JA.

Mol Biol Evol. 2012 Aug;29(8):1987-2000. doi: 10.1093/molbev/mss066. Epub 2012 Feb 14.

PMID:
22334577
13.

Differences between Cryptococcus neoformans and Cryptococcus gattii in the Molecular Mechanisms Governing Utilization of D-Amino Acids as the Sole Nitrogen Source.

Chang YC, Khanal Lamichhane A, Bradley J, Rodgers L, Ngamskulrungroj P, Kwon-Chung KJ.

PLoS One. 2015 Jul 1;10(7):e0131865. doi: 10.1371/journal.pone.0131865. eCollection 2015.

14.

Mapping the Evolution of Hypervirulent Klebsiella pneumoniae.

Struve C, Roe CC, Stegger M, Stahlhut SG, Hansen DS, Engelthaler DM, Andersen PS, Driebe EM, Keim P, Krogfelt KA.

MBio. 2015 Jul 21;6(4):e00630. doi: 10.1128/mBio.00630-15.

15.

Genome-Wide Transcription Study of Cryptococcus neoformans H99 Clinical Strain versus Environmental Strains.

Movahed E, Munusamy K, Tan GM, Looi CY, Tay ST, Wong WF.

PLoS One. 2015 Sep 11;10(9):e0137457. doi: 10.1371/journal.pone.0137457. eCollection 2015.

16.

Congenic strains of the filamentous form of Cryptococcus neoformans for studies of fungal morphogenesis and virulence.

Zhai B, Zhu P, Foyle D, Upadhyay S, Idnurm A, Lin X.

Infect Immun. 2013 Jul;81(7):2626-37. doi: 10.1128/IAI.00259-13. Epub 2013 May 13.

17.

Cryptococcus neoformans requires the ESCRT protein Vps23 for iron acquisition from heme, for capsule formation, and for virulence.

Hu G, Caza M, Cadieux B, Chan V, Liu V, Kronstad J.

Infect Immun. 2013 Jan;81(1):292-302. doi: 10.1128/IAI.01037-12. Epub 2012 Nov 6.

18.

Evasion of Innate Immune Responses by the Highly Virulent Cryptococcus gattii by Altering Capsule Glucuronoxylomannan Structure.

Urai M, Kaneko Y, Ueno K, Okubo Y, Aizawa T, Fukazawa H, Sugita T, Ohno H, Shibuya K, Kinjo Y, Miyazaki Y.

Front Cell Infect Microbiol. 2016 Jan 6;5:101. doi: 10.3389/fcimb.2015.00101. eCollection 2015.

19.

Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis.

Lee A, Toffaletti DL, Tenor J, Soderblom EJ, Thompson JW, Moseley MA, Price M, Perfect JR.

Infect Immun. 2010 Oct;78(10):4213-25. doi: 10.1128/IAI.00551-10. Epub 2010 Aug 9.

20.

Regulatory diversity of TUP1 in Cryptococcus neoformans.

Lee H, Chang YC, Varma A, Kwon-Chung KJ.

Eukaryot Cell. 2009 Dec;8(12):1901-8. doi: 10.1128/EC.00256-09. Epub 2009 Oct 9.

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