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Items: 1 to 20 of 113

1.

mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production.

Maseda D, Johnson EM, Nyhoff LE, Baron B, Kojima F, Wilhelm AJ, Ward MR, Woodward JG, Brand DD, Crofford LJ.

J Immunol. 2018 Jan 15;200(2):725-736. doi: 10.4049/jimmunol.1601808. Epub 2017 Dec 13.

2.

Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway.

Samuchiwal SK, Balestrieri B, Raff H, Boyce JA.

J Biol Chem. 2017 May 19;292(20):8195-8206. doi: 10.1074/jbc.M116.769422. Epub 2017 Mar 24.

3.

Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor.

Duffy MM, Pindjakova J, Hanley SA, McCarthy C, Weidhofer GA, Sweeney EM, English K, Shaw G, Murphy JM, Barry FP, Mahon BP, Belton O, Ceredig R, Griffin MD.

Eur J Immunol. 2011 Oct;41(10):2840-51. doi: 10.1002/eji.201141499. Epub 2011 Aug 30.

4.

COX/PGE(2) axis critically regulates effects of LPS on eosinophilia-associated cytokine production in nasal polyps.

Higaki T, Okano M, Fujiwara T, Makihara S, Kariya S, Noda Y, Haruna T, Nishizaki K.

Clin Exp Allergy. 2012 Aug;42(8):1217-26. doi: 10.1111/j.1365-2222.2012.04015.x.

5.

Differential requirements for Th1 and Th17 responses to a systemic self-antigen.

Katzman SD, Gallo E, Hoyer KK, Abbas AK.

J Immunol. 2011 Apr 15;186(8):4668-73. doi: 10.4049/jimmunol.1003786. Epub 2011 Mar 14.

6.

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R.

J Exp Med. 2009 Mar 16;206(3):535-48. doi: 10.1084/jem.20082293. Epub 2009 Mar 9.

7.

Prostaglandin E2 and IL-23 plus IL-1β differentially regulate the Th1/Th17 immune response of human CD161(+) CD4(+) memory T cells.

Barrie A, Khare A, Henkel M, Zhang Y, Barmada MM, Duerr R, Ray A.

Clin Transl Sci. 2011 Aug;4(4):268-73. doi: 10.1111/j.1752-8062.2011.00300.x.

8.

The paracrine immunomodulatory interactions between the human dental pulp derived mesenchymal stem cells and CD4 T cell subsets.

Özdemir AT, Özgül Özdemir RB, Kırmaz C, Sarıboyacı AE, Ünal Halbutoğlları ZS, Özel C, Karaöz E.

Cell Immunol. 2016 Dec;310:108-115. doi: 10.1016/j.cellimm.2016.08.008. Epub 2016 Aug 24.

PMID:
27576175
9.

E prostanoid 2 (EP2)/EP4-mediated suppression of antigen-specific human T-cell responses by prostaglandin E2.

Okano M, Sugata Y, Fujiwara T, Matsumoto R, Nishibori M, Shimizu K, Maeda M, Kimura Y, Kariya S, Hattori H, Yokoyama M, Kino K, Nishizaki K.

Immunology. 2006 Jul;118(3):343-52.

10.

Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells.

Kofler DM, Marson A, Dominguez-Villar M, Xiao S, Kuchroo VK, Hafler DA.

J Clin Invest. 2014 Jun;124(6):2513-22. doi: 10.1172/JCI72973. Epub 2014 May 8.

11.

The IL17A and IL17F loci have divergent histone modifications and are differentially regulated by prostaglandin E2 in Th17 cells.

Adamik J, Henkel M, Ray A, Auron PE, Duerr R, Barrie A.

Cytokine. 2013 Oct;64(1):404-12. doi: 10.1016/j.cyto.2013.05.010. Epub 2013 Jun 22.

12.

Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cells.

Napolitani G, Acosta-Rodriguez EV, Lanzavecchia A, Sallusto F.

Eur J Immunol. 2009 May;39(5):1301-12. doi: 10.1002/eji.200838969.

13.

Efficient T-cell priming and activation requires signaling through prostaglandin E2 (EP) receptors.

Sreeramkumar V, Hons M, Punzón C, Stein JV, Sancho D, Fresno M, Cuesta N.

Immunol Cell Biol. 2016 Jan;94(1):39-51. doi: 10.1038/icb.2015.62. Epub 2015 Jun 8.

PMID:
26051593
14.

Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.

Steinbach EC, Kobayashi T, Russo SM, Sheikh SZ, Gipson GR, Kennedy ST, Uno JK, Mishima Y, Borst LB, Liu B, Herfarth H, Ting JP, Sartor RB, Plevy SE.

J Immunol. 2014 Apr 15;192(8):3958-68. doi: 10.4049/jimmunol.1301533. Epub 2014 Mar 14.

15.

mPGES-1-Mediated Production of PGE2 and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation.

Maseda D, Banerjee A, Johnson EM, Washington MK, Kim H, Lau KS, Crofford LJ.

Front Immunol. 2018 Dec 14;9:2954. doi: 10.3389/fimmu.2018.02954. eCollection 2018.

16.

Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide.

Bonfill-Teixidor E, Otxoa-de-Amezaga A, Font-Nieves M, Sans-Fons MG, Planas AM.

J Neuroinflammation. 2017 Jan 5;14(1):3. doi: 10.1186/s12974-016-0780-7.

17.

Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin-2.

Hilkens CM, Vermeulen H, van Neerven RJ, Snijdewint FG, Wierenga EA, Kapsenberg ML.

Eur J Immunol. 1995 Jan;25(1):59-63.

PMID:
7843254
18.

The cyclooxygenase-2-prostaglandin E2 pathway maintains senescence of chronic obstructive pulmonary disease fibroblasts.

Dagouassat M, Gagliolo JM, Chrusciel S, Bourin MC, Duprez C, Caramelle P, Boyer L, Hue S, Stern JB, Validire P, Longrois D, Norel X, Dubois-Randé JL, Le Gouvello S, Adnot S, Boczkowski J.

Am J Respir Crit Care Med. 2013 Apr 1;187(7):703-14. doi: 10.1164/rccm.201208-1361OC.

PMID:
23328527
19.

Increased Th17 cells in the tumor microenvironment is mediated by IL-23 via tumor-secreted prostaglandin E2.

Qian X, Gu L, Ning H, Zhang Y, Hsueh EC, Fu M, Hu X, Wei L, Hoft DF, Liu J.

J Immunol. 2013 Jun 1;190(11):5894-902. doi: 10.4049/jimmunol.1203141. Epub 2013 May 3.

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