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Items: 1 to 20 of 38

1.

Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake.

Cripps MJ, Hanna K, Lavilla C Jr, Sayers SR, Caton PW, Sims C, De Girolamo L, Sale C, Turner MD.

Sci Rep. 2017 Oct 17;7(1):13313. doi: 10.1038/s41598-017-13649-w.

2.

Neuronal nitric oxide synthase protects the pancreatic beta cell from glucolipotoxicity-induced endoplasmic reticulum stress and apoptosis.

Bachar E, Ariav Y, Cerasi E, Kaiser N, Leibowitz G.

Diabetologia. 2010 Oct;53(10):2177-87. doi: 10.1007/s00125-010-1833-6. Epub 2010 Jul 2.

PMID:
20596694
3.

Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells.

Barlow J, Solomon TPJ.

Metabolism. 2019 Feb;91:1-9. doi: 10.1016/j.metabol.2018.11.004. Epub 2018 Nov 13.

PMID:
30445139
4.

TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats.

Tsujihata Y, Ito R, Suzuki M, Harada A, Negoro N, Yasuma T, Momose Y, Takeuchi K.

J Pharmacol Exp Ther. 2011 Oct;339(1):228-37. doi: 10.1124/jpet.111.183772. Epub 2011 Jul 13.

PMID:
21752941
5.

Pancreatic β-cell dysfunction, expression of iNOS and the effect of phosphodiesterase inhibitors in human pancreatic islets of type 2 diabetes.

Muhammed SJ, Lundquist I, Salehi A.

Diabetes Obes Metab. 2012 Nov;14(11):1010-9. doi: 10.1111/j.1463-1326.2012.01632.x. Epub 2012 Jul 4.

PMID:
22687049
6.
8.

Omega-3 fatty acids control productions of superoxide and nitrogen oxide and insulin content in INS-1E cells.

Graciano MF, Leonelli M, Curi R, R Carpinelli A.

J Physiol Biochem. 2016 Dec;72(4):699-710. Epub 2016 Jul 29.

PMID:
27474043
9.

Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass.

Fontés G, Zarrouki B, Hagman DK, Latour MG, Semache M, Roskens V, Moore PC, Prentki M, Rhodes CJ, Jetton TL, Poitout V.

Diabetologia. 2010 Nov;53(11):2369-79. doi: 10.1007/s00125-010-1850-5. Epub 2010 Jul 14.

10.

Plasma carnosine, but not muscle carnosine, attenuates high-fat diet-induced metabolic stress.

Stegen S, Stegen B, Aldini G, Altomare A, Cannizzaro L, Orioli M, Gerlo S, Deldicque L, Ramaekers M, Hespel P, Derave W.

Appl Physiol Nutr Metab. 2015 Sep;40(9):868-76. doi: 10.1139/apnm-2015-0042.

PMID:
26307517
11.

Glucose-dependent expansion of pancreatic beta-cells by the protein p8 in vitro and in vivo.

Päth G, Opel A, Gehlen M, Rothhammer V, Niu X, Limbert C, Romfeld L, Hügl S, Knoll A, Brendel MD, Bretzel RG, Seufert J.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1168-76. Epub 2006 Jul 5.

12.
13.

Carnosine metabolism in diabetes is altered by reactive metabolites.

Peters V, Lanthaler B, Amberger A, Fleming T, Forsberg E, Hecker M, Wagner AH, Yue WW, Hoffmann GF, Nawroth P, Zschocke J, Schmitt CP.

Amino Acids. 2015 Nov;47(11):2367-76. doi: 10.1007/s00726-015-2024-z. Epub 2015 Jun 17.

PMID:
26081982
14.

Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?

Doliba NM, Liu Q, Li C, Chen J, Chen P, Liu C, Frederick DW, Baur JA, Bennett MJ, Naji A, Matschinsky FM.

Mol Metab. 2015 Oct 8;4(12):926-39. doi: 10.1016/j.molmet.2015.09.010. eCollection 2015 Dec.

15.

Oleic acid and peanut oil high in oleic acid reverse the inhibitory effect of insulin production of the inflammatory cytokine TNF-alpha both in vitro and in vivo systems.

Vassiliou EK, Gonzalez A, Garcia C, Tadros JH, Chakraborty G, Toney JH.

Lipids Health Dis. 2009 Jun 26;8:25. doi: 10.1186/1476-511X-8-25.

17.

[Establishment and application of the model of islet impaired by NO free radical released from streptozotocin].

Qian FY, Ouyang F, Fu DX, Ren TR.

Sheng Wu Gong Cheng Xue Bao. 2003 May;19(3):349-52. Chinese.

PMID:
15969020
18.

Constitutively active heat shock factor 1 enhances glucose-driven insulin secretion.

Uchiyama T, Tomono S, Utsugi T, Ohyama Y, Nakamura T, Tomura H, Kawazu S, Okajima F, Kurabayashi M.

Metabolism. 2011 Jun;60(6):789-98. doi: 10.1016/j.metabol.2010.07.029. Epub 2010 Sep 3.

PMID:
20817212
19.

Skeletal muscle insulin resistance associated with cholesterol-induced activation of macrophages is prevented by high density lipoprotein.

Carey AL, Siebel AL, Reddy-Luthmoodoo M, Natoli AK, D'Souza W, Meikle PJ, Sviridov D, Drew BG, Kingwell BA.

PLoS One. 2013;8(2):e56601. doi: 10.1371/journal.pone.0056601. Epub 2013 Feb 21.

20.

Inhibition of glucagon secretion.

Young A.

Adv Pharmacol. 2005;52:151-71. Review.

PMID:
16492545

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