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Items: 1 to 20 of 106

1.

Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.

Trabanelli S, Chevalier MF, Martinez-Usatorre A, Gomez-Cadena A, Salomé B, Lecciso M, Salvestrini V, Verdeil G, Racle J, Papayannidis C, Morita H, Pizzitola I, Grandclément C, Bohner P, Bruni E, Girotra M, Pallavi R, Falvo P, Leibundgut EO, Baerlocher GM, Carlo-Stella C, Taurino D, Santoro A, Spinelli O, Rambaldi A, Giarin E, Basso G, Tresoldi C, Ciceri F, Gfeller D, Akdis CA, Mazzarella L, Minucci S, Pelicci PG, Marcenaro E, McKenzie ANJ, Vanhecke D, Coukos G, Mavilio D, Curti A, Derré L, Jandus C.

Nat Commun. 2017 Sep 19;8(1):593. doi: 10.1038/s41467-017-00678-2.

2.

The prostaglandin D₂ receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung.

Wojno ED, Monticelli LA, Tran SV, Alenghat T, Osborne LC, Thome JJ, Willis C, Budelsky A, Farber DL, Artis D.

Mucosal Immunol. 2015 Nov;8(6):1313-23. doi: 10.1038/mi.2015.21. Epub 2015 Apr 8.

3.

Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production.

Salimi M, Xue L, Jolin H, Hardman C, Cousins DJ, McKenzie AN, Ogg GS.

J Immunol. 2016 Jan 1;196(1):45-54. doi: 10.4049/jimmunol.1501102. Epub 2015 Nov 18.

4.

Cysteinyl leukotriene E4 activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D2 and epithelial cytokines.

Salimi M, Stöger L, Liu W, Go S, Pavord I, Klenerman P, Ogg G, Xue L.

J Allergy Clin Immunol. 2017 Oct;140(4):1090-1100.e11. doi: 10.1016/j.jaci.2016.12.958. Epub 2017 Jan 20.

5.

B7H6-derived peptides trigger TNF-α-dependent immunostimulatory activity of lymphocytic NK92-MI cells.

Phillips M, Romeo F, Bitsaktsis C, Sabatino D.

Biopolymers. 2016 Sep;106(5):658-72. doi: 10.1002/bip.22879.

PMID:
27216712
6.

MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation.

Johansson K, Malmhäll C, Ramos-Ramírez P, Rådinger M.

J Allergy Clin Immunol. 2017 Mar;139(3):1007-1016.e9. doi: 10.1016/j.jaci.2016.06.035. Epub 2016 Aug 1.

PMID:
27492144
7.

B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity.

Wu MR, Zhang T, DeMars LR, Sentman CL.

Gene Ther. 2015 Aug;22(8):675-84. doi: 10.1038/gt.2015.29. Epub 2015 Apr 1.

8.

Cytokine-induced endogenous production of prostaglandin D2 is essential for human group 2 innate lymphoid cell activation.

Maric J, Ravindran A, Mazzurana L, Van Acker A, Rao A, Kokkinou E, Ekoff M, Thomas D, Fauland A, Nilsson G, Wheelock CE, Dahlén SE, Ferreirós N, Geisslinger G, Friberg D, Heinemann A, Konya V, Mjösberg J.

J Allergy Clin Immunol. 2018 Dec 19. pii: S0091-6749(18)32774-X. doi: 10.1016/j.jaci.2018.10.069. [Epub ahead of print]

PMID:
30578872
9.

Activation of group 2 innate lymphoid cells exacerbates and confers corticosteroid resistance to mouse nasal type 2 inflammation.

Morikawa T, Fukuoka A, Matsushita K, Yasuda K, Iwasaki N, Akasaki S, Fujieda S, Yoshimoto T.

Int Immunol. 2017 May 1;29(5):221-233. doi: 10.1093/intimm/dxx030.

PMID:
28541554
10.

Group 2 innate lymphoid cells and CD4+ T cells cooperate to mediate type 2 immune response in mice.

Drake LY, Iijima K, Kita H.

Allergy. 2014 Oct;69(10):1300-7. doi: 10.1111/all.12446. Epub 2014 Jun 17.

11.

The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury.

Zhang C, Wang S, Li J, Zhang W, Zheng L, Yang C, Zhu T, Rong R.

Cell Death Dis. 2017 Mar 23;8(3):e2695. doi: 10.1038/cddis.2017.86.

12.

NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure.

Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D.

PLoS One. 2015 Aug 4;10(8):e0134568. doi: 10.1371/journal.pone.0134568. eCollection 2015.

13.

Enhanced circulating ILC2s and MDSCs may contribute to ensure maintenance of Th2 predominant in patients with lung cancer.

Wu Y, Yan Y, Su Z, Bie Q, Chen X, Barnie PA, Guo Q, Wang S, Xu H.

Mol Med Rep. 2017 Jun;15(6):4374-4381. doi: 10.3892/mmr.2017.6537. Epub 2017 May 2.

PMID:
28487978
14.

IL-2 is a critical regulator of group 2 innate lymphoid cell function during pulmonary inflammation.

Roediger B, Kyle R, Tay SS, Mitchell AJ, Bolton HA, Guy TV, Tan SY, Forbes-Blom E, Tong PL, Köller Y, Shklovskaya E, Iwashima M, McCoy KD, Le Gros G, Fazekas de St Groth B, Weninger W.

J Allergy Clin Immunol. 2015 Dec;136(6):1653-1663.e7. doi: 10.1016/j.jaci.2015.03.043. Epub 2015 May 27.

PMID:
26025126
15.

Interleukin-33/ST2 axis promotes breast cancer growth and metastases by facilitating intratumoral accumulation of immunosuppressive and innate lymphoid cells.

Jovanovic IP, Pejnovic NN, Radosavljevic GD, Pantic JM, Milovanovic MZ, Arsenijevic NN, Lukic ML.

Int J Cancer. 2014 Apr 1;134(7):1669-82. doi: 10.1002/ijc.28481. Epub 2013 Oct 10.

16.

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells.

Klein Wolterink RG, Serafini N, van Nimwegen M, Vosshenrich CA, de Bruijn MJ, Fonseca Pereira D, Veiga Fernandes H, Hendriks RW, Di Santo JP.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10240-5. doi: 10.1073/pnas.1217158110. Epub 2013 Jun 3.

17.

Allogeneic and xenogeneic anti-tumor effect of callithrix jacchus natural killer cells is dependent on NKp30 and B7-H6 interaction.

Müller T, Schlahsa L, Zhang HJ, Skaik Y, Eiz-Vesper B, Immenschuh S, Blasczyk R, Figueiredo C.

J Biol Regul Homeost Agents. 2014 Apr-Jun;28(2):183-93.

PMID:
25001651
18.

Development of unique cytotoxic chimeric antigen receptors based on human scFv targeting B7H6.

Hua CK, Gacerez AT, Sentman CL, Ackerman ME.

Protein Eng Des Sel. 2017 Oct 1;30(10):713-721. doi: 10.1093/protein/gzx051.

19.

At the bench: understanding group 2 innate lymphoid cells in disease.

Doherty TA.

J Leukoc Biol. 2015 Mar;97(3):455-67. doi: 10.1189/jlb.5BT0814-374R. Epub 2014 Dec 3. Review.

20.

Protein kinase Cθ controls type 2 innate lymphoid cell and TH2 responses to house dust mite allergen.

Madouri F, Chenuet P, Beuraud C, Fauconnier L, Marchiol T, Rouxel N, Ledru A, Gallerand M, Lombardi V, Mascarell L, Marquant Q, Apetoh L, Erard F, Le Bert M, Trovero F, Quesniaux VFJ, Ryffel B, Togbe D.

J Allergy Clin Immunol. 2017 May;139(5):1650-1666. doi: 10.1016/j.jaci.2016.08.044. Epub 2016 Oct 14.

PMID:
27746240

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