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Palliative Care and Phase 1 Trials: Intervention to Improve Quality of Life and Provide Education

Ferrell BR, Chung V, Koczywas M, Williams AC, Gallagher D, Fischer P, Smith TJ.

Clin J Oncol Nurs. 2017 Aug 1;21(4):473-479. doi: 10.1188/17.CJON.473-479.


Feasibility of a palliative care intervention for cancer patients in Phase I clinical trials.

Sun V, Cooke L, Chung V, Uman G, Smith TJ, Ferrell B.

J Palliat Med. 2014 Dec;17(12):1365-8. doi: 10.1089/jpm.2014.0108.


Effects of a palliative care intervention on clinical outcomes in patients with advanced cancer: the Project ENABLE II randomized controlled trial.

Bakitas M, Lyons KD, Hegel MT, Balan S, Brokaw FC, Seville J, Hull JG, Li Z, Tosteson TD, Byock IR, Ahles TA.

JAMA. 2009 Aug 19;302(7):741-9. doi: 10.1001/jama.2009.1198.


Characteristics of Participants Enrolled onto a Randomized Controlled Trial of Palliative Care for Patients on Phase I Studies.

Ferrell BR, Paterson CL, Hughes MT, Chung V, Koczywas M, Smith TJ.

J Palliat Med. 2017 Dec;20(12):1338-1344. doi: 10.1089/jpm.2017.0158. Epub 2017 Jun 13.


Patient perspectives on participation in the ENABLE II randomized controlled trial of a concurrent oncology palliative care intervention: benefits and burdens.

Maloney C, Lyons KD, Li Z, Hegel M, Ahles TA, Bakitas M.

Palliat Med. 2013 Apr;27(4):375-83. doi: 10.1177/0269216312445188. Epub 2012 May 9.


Interdisciplinary Palliative Care for Patients With Lung Cancer.

Ferrell B, Sun V, Hurria A, Cristea M, Raz DJ, Kim JY, Reckamp K, Williams AC, Borneman T, Uman G, Koczywas M.

J Pain Symptom Manage. 2015 Dec;50(6):758-67. doi: 10.1016/j.jpainsymman.2015.07.005. Epub 2015 Aug 19.


A phase II study in advanced cancer patients to evaluate the early transition to palliative care (the PREPArE trial): protocol study for a randomized controlled trial.

do Carmo TM, Paiva BS, de Siqueira MR, da Rosa Lde T, de Oliveira CZ, Nascimento MS, Paiva CE.

Trials. 2015 Apr 12;16:160. doi: 10.1186/s13063-015-0655-8.


Integrating Palliative Care Into Oncology: A Way Forward.

Ramchandran K, Tribett E, Dietrich B, Von Roenn J.

Cancer Control. 2015 Oct;22(4):386-95. Review.


Early Palliative Care-Health services research and implementation of sustainable changes: the study protocol of the EVI project.

Meffert C, Gaertner J, Seibel K, Jors K, Bardenheuer H, Buchheidt D, Mayer-Steinacker R, Viehrig M, Paul C, Stock S, Xander C, Becker G.

BMC Cancer. 2015 May 29;15:443. doi: 10.1186/s12885-015-1453-0.


The effect of real-time electronic monitoring of patient-reported symptoms and clinical syndromes in outpatient workflow of medical oncologists: E-MOSAIC, a multicenter cluster-randomized phase III study (SAKK 95/06).

Strasser F, Blum D, von Moos R, Cathomas R, Ribi K, Aebi S, Betticher D, Hayoz S, Klingbiel D, Brauchli P, Haefner M, Mauri S, Kaasa S, Koeberle D; Swiss Group for Clinical Cancer Research (SAKK).

Ann Oncol. 2016 Feb;27(2):324-32. doi: 10.1093/annonc/mdv576. Epub 2015 Dec 8.


Nurse-facilitated preparation and life completion interventions are acceptable and feasible in the Australian palliative care setting: results from a phase 2 trial.

Keall RM, Butow PN, Steinhauser KE, Clayton JM.

Cancer Nurs. 2013 May-Jun;36(3):E39-46. doi: 10.1097/NCC.0b013e3182664c7a.


Timing of palliative care referral and symptom burden in phase 1 cancer patients: a retrospective cohort study.

Hui D, Parsons H, Nguyen L, Palla SL, Yennurajalingam S, Kurzrock R, Bruera E.

Cancer. 2010 Sep 15;116(18):4402-9. doi: 10.1002/cncr.25389.


Integrating palliative care into active cancer treatment.

Mazanec P, Prince-Paul M.

Semin Oncol Nurs. 2014 Nov;30(4):203-11. doi: 10.1016/j.soncn.2014.08.002. Review.


The impact of disease-related symptoms and palliative care concerns on health-related quality of life in multiple myeloma: a multi-centre study.

Ramsenthaler C, Osborne TR, Gao W, Siegert RJ, Edmonds PM, Schey SA, Higginson IJ.

BMC Cancer. 2016 Jul 7;16:427. doi: 10.1186/s12885-016-2410-2.


Interdisciplinary palliative care intervention in metastatic non-small-cell lung cancer.

Koczywas M, Cristea M, Thomas J, McCarty C, Borneman T, Del Ferraro C, Sun V, Uman G, Ferrell B.

Clin Lung Cancer. 2013 Nov;14(6):736-44. doi: 10.1016/j.cllc.2013.06.008. Epub 2013 Jul 18.


Implementing a palliative care trial in advanced COPD: a feasibility assessment (the COPD IMPACT study).

Horton R, Rocker G, Dale A, Young J, Hernandez P, Sinuff T.

J Palliat Med. 2013 Jan;16(1):67-73. doi: 10.1089/jpm.2012.0285.


Structured, intensive education maximising engagement, motivation and long-term change for children and young people with diabetes: a cluster randomised controlled trial with integral process and economic evaluation - the CASCADE study.

Christie D, Thompson R, Sawtell M, Allen E, Cairns J, Smith F, Jamieson E, Hargreaves K, Ingold A, Brooks L, Wiggins M, Oliver S, Jones R, Elbourne D, Santos A, Wong IC, O'Neill S, Strange V, Hindmarsh P, Annan F, Viner R.

Health Technol Assess. 2014 Mar;18(20):1-202. doi: 10.3310/hta18200.


Early implementation of palliative care can improve patient outcomes.

Glare PA.

J Natl Compr Canc Netw. 2013 Mar;11 Suppl 1:S3-9.


Effect of Inpatient Palliative Care on Quality of Life 2 Weeks After Hematopoietic Stem Cell Transplantation: A Randomized Clinical Trial.

El-Jawahri A, LeBlanc T, VanDusen H, Traeger L, Greer JA, Pirl WF, Jackson VA, Telles J, Rhodes A, Spitzer TR, McAfee S, Chen YA, Lee SS, Temel JS.

JAMA. 2016 Nov 22;316(20):2094-2103. doi: 10.1001/jama.2016.16786.


Do phase 1 patients have greater needs for palliative care compared with other cancer patients?

Finlay E, Lu HL, Henderson HR, O'Dwyer PJ, Casarett DJ.

Cancer. 2009 Jan 15;115(2):446-53. doi: 10.1002/cncr.24025. Erratum in: Cancer. 2014 Jan 1;120(1):154. Henderson, Hope [corrected to Henderson, Hope R].

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