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Items: 1 to 20 of 119

1.

A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma.

Wagner J, Pfannenstiel V, Waldmann A, Bergs JWJ, Brill B, Huenecke S, Klingebiel T, Rödel F, Buchholz CJ, Wels WS, Bader P, Ullrich E.

Front Immunol. 2017 Jun 12;8:676. doi: 10.3389/fimmu.2017.00676. eCollection 2017.

2.

Highly efficient IL-21 and feeder cell-driven ex vivo expansion of human NK cells with therapeutic activity in a xenograft mouse model of melanoma.

Granzin M, Stojanovic A, Miller M, Childs R, Huppert V, Cerwenka A.

Oncoimmunology. 2016 Aug 5;5(9):e1219007. eCollection 2016.

3.

Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation.

Granzin M, Wagner J, Köhl U, Cerwenka A, Huppert V, Ullrich E.

Front Immunol. 2017 Apr 26;8:458. doi: 10.3389/fimmu.2017.00458. eCollection 2017. Review.

4.

An Uncoupling of Canonical Phenotypic Markers and Functional Potency of Ex Vivo-Expanded Natural Killer Cells.

Lieberman NAP, DeGolier K, Haberthur K, Chinn H, Moyes KW, Bouchlaka MN, Walker KL, Capitini CM, Crane CA.

Front Immunol. 2018 Feb 2;9:150. doi: 10.3389/fimmu.2018.00150. eCollection 2018.

5.

Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells.

Boerman GH, van Ostaijen-ten Dam MM, Kraal KC, Santos SJ, Ball LM, Lankester AC, Schilham MW, Egeler RM, van Tol MJ.

Cancer Immunol Immunother. 2015 May;64(5):573-83. doi: 10.1007/s00262-015-1657-9. Epub 2015 Feb 18.

6.

Combined IL-15 and IL-12 drives the generation of CD34+-derived natural killer cells with superior maturation and alloreactivity potential following adoptive transfer.

Cany J, van der Waart AB, Spanholtz J, Tordoir M, Jansen JH, van der Voort R, Schaap NM, Dolstra H.

Oncoimmunology. 2015 Apr 1;4(7):e1017701. eCollection 2015 Jul.

7.

Multiple effects of IL-21 on human NK cells in ex vivo expansion.

Li Q, Ye LJ, Ren HL, Huyan T, Li J, Shi JL, Huang QS.

Immunobiology. 2015 Jul;220(7):876-88. doi: 10.1016/j.imbio.2015.01.009. Epub 2015 Jan 31.

PMID:
25758713
8.

Endogenous IL-2 production by natural killer cells maintains cytotoxic and proliferative capacity following retroviral-mediated gene transfer.

Miller JS, Tessmer-Tuck J, Blake N, Lund J, Scott A, Blazar BR, Orchard PJ.

Exp Hematol. 1997 Oct;25(11):1140-8.

PMID:
9328450
9.

The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells.

Fischer K, Tognarelli S, Roesler S, Boedicker C, Schubert R, Steinle A, Klingebiel T, Bader P, Fulda S, Ullrich E.

Front Immunol. 2017 Mar 7;8:202. doi: 10.3389/fimmu.2017.00202. eCollection 2017.

10.
11.

Ex vivo expansion of natural killer cells using cryopreserved irradiated feeder cells.

Baek HJ, Kim JS, Yoon M, Lee JJ, Shin MG, Ryang DW, Kook H, Kim SK, Cho D.

Anticancer Res. 2013 May;33(5):2011-9.

PMID:
23645750
12.

Stable transduction of the interleukin-2 gene into human natural killer cell lines and their phenotypic and functional characterization in vitro and in vivo.

Nagashima S, Mailliard R, Kashii Y, Reichert TE, Herberman RB, Robbins P, Whiteside TL.

Blood. 1998 May 15;91(10):3850-61.

13.

Characterization of natural killer and natural killer-like T cells derived from ex vivo expanded and activated cord blood mononuclear cells: implications for adoptive cellular immunotherapy.

Ayello J, van de Ven C, Cairo E, Hochberg J, Baxi L, Satwani P, Cairo MS.

Exp Hematol. 2009 Oct;37(10):1216-29. doi: 10.1016/j.exphem.2009.07.009. Epub 2009 Jul 26.

PMID:
19638292
14.

Immunophenotypic and functional characterization of ex vivo expanded natural killer cells for clinical use in acute lymphoblastic leukemia patients.

Peragine N, Torelli GF, Mariglia P, Pauselli S, Vitale A, Guarini A, Foà R.

Cancer Immunol Immunother. 2015 Feb;64(2):201-11. doi: 10.1007/s00262-014-1614-z. Epub 2014 Oct 24.

PMID:
25341808
15.

Autologous Immune Enhancement Therapy for Cancer - Our experience since 2004.

Terunuma H.

J Stem Cells Regen Med. 2012 Nov 26;8(3):205-6. eCollection 2012.

PMID:
24693200
16.

Stem cell factor enhances interleukin-2-mediated expansion of murine natural killer cells in vivo.

Fehniger TA, Carson WE, Mrózek E, Caligiuri MA.

Blood. 1997 Nov 1;90(9):3647-53.

17.
19.

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells.

Denman CJ, Senyukov VV, Somanchi SS, Phatarpekar PV, Kopp LM, Johnson JL, Singh H, Hurton L, Maiti SN, Huls MH, Champlin RE, Cooper LJ, Lee DA.

PLoS One. 2012;7(1):e30264. doi: 10.1371/journal.pone.0030264. Epub 2012 Jan 18.

20.

Costimulation of human natural killer cell proliferation: role of accessory cytokines and cell contact-dependent signals.

Robertson MJ, Cameron C, Lazo S, Cochran KJ, Voss SD, Ritz J.

Nat Immun. 1996-1997;15(5):213-26.

PMID:
9390270

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