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High mobility group box 1: Biomarker of inhaled corticosteroid treatment response in children with moderate-severe asthma.

Manti S, Leonardi S, Parisi GF, De Vivo D, Salpietro A, Spinuzza A, Arrigo T, Salpietro C, Cuppari C.

Allergy Asthma Proc. 2017 May 1;38(3):197-203. doi: 10.2500/aap.2017.38.4047.


Sputum high mobility group box-1 in asthmatic children: a noninvasive sensitive biomarker reflecting disease status.

Cuppari C, Manti S, Chirico V, Caruso R, Salpietro V, Giacchi V, Laganà F, Arrigo T, Salpietro C, Leonardi S.

Ann Allergy Asthma Immunol. 2015 Aug;115(2):103-7. doi: 10.1016/j.anai.2015.06.008.


Relationship between Fractional Exhaled Nitric Oxide Level and Efficacy of Inhaled Corticosteroid in Asthma-COPD Overlap Syndrome Patients with Different Disease Severity.

Feng JX, Lin Y, Lin J, He SS, Chen MF, Wu XM, Xu YZ.

J Korean Med Sci. 2017 Mar;32(3):439-447. doi: 10.3346/jkms.2017.32.3.439.


High mobility group protein B1 (HMGB1) in Asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls.

Hou C, Zhao H, Liu L, Li W, Zhou X, Lv Y, Shen X, Liang Z, Cai S, Zou F.

Mol Med. 2011;17(7-8):807-15. doi: 10.2119/molmed.2010.00173. Epub 2011 Mar 3.


Exhaled nitric oxide for monitoring childhood asthma inflammation compared to sputum analysis, serum interleukins and pulmonary function.

Paro-Heitor ML, Bussamra MH, Saraiva-Romanholo BM, Martins MA, Okay TS, Rodrigues JC.

Pediatr Pulmonol. 2008 Feb;43(2):134-41.


[Changes of HMGB1 and RAGE in induced sputum from patients with bronchial asthma].

Cheng Z, Dai LL, Cao DF, Wu QG, Song YN, Kang Y, Xia J, Si JM, Chen CY.

Zhonghua Yi Xue Za Zhi. 2011 Jun 14;91(22):1538-42. Chinese.


[Levels of HMGB1 in induced sputum from patients with asthma and chronic obstructive pulmonary disease].

Cheng Z, Kang Y, Wu QG, Dai LL, Song YN, Xia J, Si JM, Chen CY.

Zhonghua Yi Xue Za Zhi. 2011 Nov 15;91(42):2981-4. Chinese.


Elevated fractional exhaled nitric oxide (FeNO) is a clinical indicator of uncontrolled asthma in children receiving inhaled corticosteroids.

Yin SS, Liu H, Gao X.

Int J Clin Pharmacol Ther. 2017 Jan;55(1):66-77. doi: 10.5414/CP202570.


Influence of cigarette smoking on airway inflammation and inhaled corticosteroid treatment in patients with asthma.

Shimoda T, Obase Y, Kishikawa R, Iwanaga T.

Allergy Asthma Proc. 2016 Jul;37(4):50-8. doi: 10.2500/aap.2016.37.3944.


A 2-year step-down withdrawal from inhaled corticosteroids in asthmatic children receiving immunotherapy.

He CH, Li X, Lin JH, Xiao Q, Yu JL, Liu YF, Jiang WH, Chen C, Deng L, Zhou J.

World J Pediatr. 2017 Dec;13(6):560-565. doi: 10.1007/s12519-017-0065-y. Epub 2017 Oct 20.


Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment in patients with overlap syndrome of COPD and asthma.

Kitaguchi Y, Komatsu Y, Fujimoto K, Hanaoka M, Kubo K.

Int J Chron Obstruct Pulmon Dis. 2012;7:283-9. doi: 10.2147/COPD.S30651. Epub 2012 Apr 12.


Association of symptom control with changes in lung function, bronchial hyperresponsiveness, and exhaled nitric oxide after inhaled corticosteroid treatment in children with asthma.

Park GM, Han HW, Kim JY, Lee E, Cho HJ, Yoon J, Hong SJ, Yang SI, Yang HJ, Yu J.

Allergol Int. 2016 Oct;65(4):439-443. doi: 10.1016/j.alit.2016.03.011. Epub 2016 May 6.


Characteristics of asthma resistant to moderate dose inhaled corticosteroid treatment on bronchial hyperresponsiveness.

Fujimoto K, Yamaguchi S, Urushibata K, Hanaoka M, Koizumi T, Honda T, Kubo K.

Intern Med. 2006;45(14):843-9. Epub 2006 Aug 15.


Biomarker-based asthma phenotypes of corticosteroid response.

Cowan DC, Taylor DR, Peterson LE, Cowan JO, Palmay R, Williamson A, Hammel J, Erzurum SC, Hazen SL, Comhair SA.

J Allergy Clin Immunol. 2015 Apr;135(4):877-83.e1. doi: 10.1016/j.jaci.2014.10.026. Epub 2014 Dec 6.


Randomised trial of once-daily vilanterol in children with asthma on inhaled corticosteroid therapy.

Oliver AJ, Covar RA, Goldfrad CH, Klein RM, Pedersen SE, Sorkness CA, Tomkins SA, Villarán C, Grigg J.

Respir Res. 2016 Apr 5;17:37. doi: 10.1186/s12931-016-0353-4.


Association of blood eosinophils and plasma periostin with FEV1 response after 3-month inhaled corticosteroid and long-acting beta2-agonist treatment in stable COPD patients.

Park HY, Lee H, Koh WJ, Kim S, Jeong I, Koo HK, Kim TH, Kim JW, Kim WJ, Oh YM, Sin DD, Lim SY, Lee SD; KOLD Study Group.

Int J Chron Obstruct Pulmon Dis. 2015 Dec 22;11:23-30. doi: 10.2147/COPD.S94797. eCollection 2016.


Sputum gene expression signature of 6 biomarkers discriminates asthma inflammatory phenotypes.

Baines KJ, Simpson JL, Wood LG, Scott RJ, Fibbens NL, Powell H, Cowan DC, Taylor DR, Cowan JO, Gibson PG.

J Allergy Clin Immunol. 2014 Apr;133(4):997-1007. doi: 10.1016/j.jaci.2013.12.1091. Epub 2014 Feb 28.


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