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Items: 1 to 20 of 126

1.

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features.

Teye EK, Sido A, Xin P, Finnberg NK, Gokare P, Kawasawa YI, Salzberg AC, Shimko S, Bayerl M, Ehmann WC, Claxton DF, Rybka WB, Drabick JJ, Wang HG, Abraham T, El-Deiry WS, Brodsky RA, J Hohl R, Pu JJ.

Oncotarget. 2017 May 2;8(18):29887-29905. doi: 10.18632/oncotarget.15136.

2.

High Expression of Human Homologue of Murine Double Minute 4 and the Short Splicing Variant, HDM4-S, in Bone Marrow in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome.

Han X, Medeiros LJ, Zhang YH, You MJ, Andreeff M, Konopleva M, Bueso-Ramos CE.

Clin Lymphoma Myeloma Leuk. 2016 Aug;16 Suppl:S30-8. doi: 10.1016/j.clml.2016.03.012. Epub 2016 Apr 1. Review.

PMID:
27155969
3.

SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS.

Inoue D, Kitaura J, Matsui H, Hou HA, Chou WC, Nagamachi A, Kawabata KC, Togami K, Nagase R, Horikawa S, Saika M, Micol JB, Hayashi Y, Harada Y, Harada H, Inaba T, Tien HF, Abdel-Wahab O, Kitamura T.

Leukemia. 2015 Apr;29(4):847-57. doi: 10.1038/leu.2014.301. Epub 2014 Oct 13.

4.

Myeloid neoplasms with isolated isochromosome 17q represent a clinicopathologic entity associated with myelodysplastic/myeloproliferative features, a high risk of leukemic transformation, and wild-type TP53.

Kanagal-Shamanna R, Bueso-Ramos CE, Barkoh B, Lu G, Wang S, Garcia-Manero G, Vadhan-Raj S, Hoehn D, Medeiros LJ, Yin CC.

Cancer. 2012 Jun 1;118(11):2879-88. doi: 10.1002/cncr.26537. Epub 2011 Oct 28.

5.

MLL gene amplification in acute myeloid leukemia and myelodysplastic syndromes is associated with characteristic clinicopathological findings and TP53 gene mutation.

Tang G, DiNardo C, Zhang L, Ravandi F, Khoury JD, Huh YO, Muzzafar T, Medeiros LJ, Wang SA, Bueso-Ramos CE.

Hum Pathol. 2015 Jan;46(1):65-73. doi: 10.1016/j.humpath.2014.09.008. Epub 2014 Oct 2.

PMID:
25387813
6.

Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions.

Quentin S, Cuccuini W, Ceccaldi R, Nibourel O, Pondarre C, Pagès MP, Vasquez N, Dubois d'Enghien C, Larghero J, Peffault de Latour R, Rocha V, Dalle JH, Schneider P, Michallet M, Michel G, Baruchel A, Sigaux F, Gluckman E, Leblanc T, Stoppa-Lyonnet D, Preudhomme C, Socié G, Soulier J.

Blood. 2011 Apr 14;117(15):e161-70. doi: 10.1182/blood-2010-09-308726. Epub 2011 Feb 16.

7.

Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome.

Boehrer S, Adès L, Tajeddine N, Hofmann WK, Kriener S, Bug G, Ottmann OG, Ruthardt M, Galluzzi L, Fouassier C, Tailler M, Olaussen KA, Gardin C, Eclache V, de Botton S, Thepot S, Fenaux P, Kroemer G.

Oncogene. 2009 Jun 4;28(22):2205-18. doi: 10.1038/onc.2009.69. Epub 2009 Apr 27.

PMID:
19398952
8.

Helicase-like transcription factor is a RUNX1 target whose downregulation promotes genomic instability and correlates with complex cytogenetic features in acute myeloid leukemia.

Cheng CK, Chan NP, Wan TS, Lam LY, Cheung CH, Wong TH, Ip RK, Wong RS, Ng MH.

Haematologica. 2016 Apr;101(4):448-57. doi: 10.3324/haematol.2015.137125. Epub 2016 Jan 22.

9.

Molecular mechanism of microRNA involvement in genesis of myelodysplastic syndrome and its transformation to acute myeloid leukemia.

Liao R, Xu Y, Chen M, Chen X, Zhan X, Sun J.

Hematology. 2013 Jul;18(4):191-7. doi: 10.1179/1607845412Y.0000000053. Epub 2013 Jan 3. Review.

PMID:
23321417
10.

SPARC silencing inhibits the growth of acute myeloid leukemia transformed from myelodysplastic syndrome via induction of cell cycle arrest and apoptosis.

Nian Q, Xiao Q, Wang L, Luo J, Chen LP, Yang ZS, Liu L.

Int J Mol Med. 2014 Apr;33(4):856-62. doi: 10.3892/ijmm.2014.1648. Epub 2014 Feb 7.

11.

Profiling three-dimensional nuclear telomeric architecture of myelodysplastic syndromes and acute myeloid leukemia defines patient subgroups.

Gadji M, Adebayo Awe J, Rodrigues P, Kumar R, Houston DS, Klewes L, Dièye TN, Rego EM, Passetto RF, de Oliveira FM, Mai S.

Clin Cancer Res. 2012 Jun 15;18(12):3293-304. doi: 10.1158/1078-0432.CCR-12-0087. Epub 2012 Apr 26.

12.

MicroRNAs and tRNA-derived fragments predict the transformation of myelodysplastic syndromes to acute myeloid leukemia.

Guo Y, Strickland SA, Mohan S, Li S, Bosompem A, Vickers KC, Zhao S, Sheng Q, Kim AS.

Leuk Lymphoma. 2017 Sep;58(9):1-15. doi: 10.1080/10428194.2016.1272680. Epub 2017 Jan 13.

14.

Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations.

Harada Y, Harada H.

J Cell Physiol. 2009 Jul;220(1):16-20. doi: 10.1002/jcp.21769. Review.

PMID:
19334039
15.

Prognostic significance of combined MN1, ERG, BAALC, and EVI1 (MEBE) expression in patients with myelodysplastic syndromes.

Thol F, Yun H, Sonntag AK, Damm F, Weissinger EM, Krauter J, Wagner K, Morgan M, Wichmann M, Göhring G, Bug G, Ottmann O, Hofmann WK, Schambach A, Schlegelberger B, Haferlach T, Bowen D, Mills K, Ganser A, Heuser M.

Ann Hematol. 2012 Aug;91(8):1221-33. doi: 10.1007/s00277-012-1457-7. Epub 2012 Apr 10.

PMID:
22488406
16.

CXCL12+ stromal cells as bone marrow niche for CD34+ hematopoietic cells and their association with disease progression in myelodysplastic syndromes.

Abe-Suzuki S, Kurata M, Abe S, Onishi I, Kirimura S, Nashimoto M, Murayama T, Hidaka M, Kitagawa M.

Lab Invest. 2014 Nov;94(11):1212-23. doi: 10.1038/labinvest.2014.110. Epub 2014 Sep 8.

17.

Mesenchymal stromal cells of myelodysplastic syndrome and acute myeloid leukemia patients have distinct genetic abnormalities compared with leukemic blasts.

Blau O, Baldus CD, Hofmann WK, Thiel G, Nolte F, Burmeister T, Türkmen S, Benlasfer O, Schümann E, Sindram A, Molkentin M, Mundlos S, Keilholz U, Thiel E, Blau IW.

Blood. 2011 Nov 17;118(20):5583-92. doi: 10.1182/blood-2011-03-343467. Epub 2011 Sep 23.

18.

Gene stage-specific expression in the microenvironment of pediatric myelodysplastic syndromes.

Roela RA, Carraro DM, Brentani HP, Kaiano JH, Simão DF, Guarnieiro R, Lopes LF, Borojevic R, Brentani MM.

Leuk Res. 2007 May;31(5):579-89. Epub 2006 Nov 7.

PMID:
17092558
19.

Replication errors in hematological neoplasias: genomic instability in progression of disease is different among different types of leukemia.

Ohyashiki JH, Ohyashiki K, Aizawa S, Kawakubo K, Shimamoto T, Iwama H, Hayashi S, Toyama K.

Clin Cancer Res. 1996 Sep;2(9):1583-9.

20.

CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes.

Reindl C, Quentmeier H, Petropoulos K, Greif PA, Benthaus T, Argiropoulos B, Mellert G, Vempati S, Duyster J, Buske C, Bohlander SK, Humphries KR, Hiddemann W, Spiekermann K.

Clin Cancer Res. 2009 Apr 1;15(7):2238-47. doi: 10.1158/1078-0432.CCR-08-1325. Epub 2009 Mar 10.

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