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Items: 1 to 20 of 88

1.

Pim1 kinase regulates c-Kit gene translation.

An N, Cen B, Cai H, Song JH, Kraft A, Kang Y.

Exp Hematol Oncol. 2016 Dec 30;5:31. doi: 10.1186/s40164-016-0060-3. eCollection 2016.

2.

Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.

An N, Lin YW, Mahajan S, Kellner JN, Wang Y, Li Z, Kraft AS, Kang Y.

Stem Cells. 2013 Jun;31(6):1202-12. doi: 10.1002/stem.1369.

3.

Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice.

An N, Kraft AS, Kang Y.

J Hematol Oncol. 2013 Jan 29;6:12. doi: 10.1186/1756-8722-6-12.

4.

Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration.

Grundler R, Brault L, Gasser C, Bullock AN, Dechow T, Woetzel S, Pogacic V, Villa A, Ehret S, Berridge G, Spoo A, Dierks C, Biondi A, Knapp S, Duyster J, Schwaller J.

J Exp Med. 2009 Aug 31;206(9):1957-70. doi: 10.1084/jem.20082074. Epub 2009 Aug 17.

5.

PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).

Decker S, Finter J, Forde AJ, Kissel S, Schwaller J, Mack TS, Kuhn A, Gray N, Follo M, Jumaa H, Burger M, Zirlik K, Pfeifer D, Miduturu CV, Eibel H, Veelken H, Dierks C.

Mol Cancer Ther. 2014 May;13(5):1231-45. doi: 10.1158/1535-7163.MCT-13-0575-T. Epub 2014 Mar 21.

6.

Evidence that the Pim1 kinase gene is a direct target of HOXA9.

Hu YL, Passegué E, Fong S, Largman C, Lawrence HJ.

Blood. 2007 Jun 1;109(11):4732-8. Epub 2007 Feb 27.

7.

Pim1 promotes human prostate cancer cell tumorigenicity and c-MYC transcriptional activity.

Kim J, Roh M, Abdulkadir SA.

BMC Cancer. 2010 Jun 1;10:248. doi: 10.1186/1471-2407-10-248.

8.

PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal.

Kobayashi M, Bai Y, Dong Y, Yu H, Chen S, Gao R, Zhang L, Yoder MC, Kapur R, Zhang ZY, Liu Y.

Stem Cells. 2014 Jul;32(7):1956-67. doi: 10.1002/stem.1672.

9.

Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool.

Zhu HH, Ji K, Alderson N, He Z, Li S, Liu W, Zhang DE, Li L, Feng GS.

Blood. 2011 May 19;117(20):5350-61. doi: 10.1182/blood-2011-01-333476. Epub 2011 Mar 30.

10.

Pim Kinase Interacts with Nonstructural 5A Protein and Regulates Hepatitis C Virus Entry.

Park C, Min S, Park EM, Lim YS, Kang S, Suzuki T, Shin EC, Hwang SB.

J Virol. 2015 Oct;89(19):10073-86. doi: 10.1128/JVI.01707-15. Epub 2015 Jul 22.

11.

Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.

Zemskova MY, Song JH, Cen B, Cerda-Infante J, Montecinos VP, Kraft AS.

Cell Signal. 2015 Jan;27(1):135-46. doi: 10.1016/j.cellsig.2014.10.010. Epub 2014 Oct 28.

12.

Regulation of the MIR155 host gene in physiological and pathological processes.

Elton TS, Selemon H, Elton SM, Parinandi NL.

Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Review.

PMID:
23246696
14.

PIM1 kinase phosphorylates the human transcription factor FOXP3 at serine 422 to negatively regulate its activity under inflammation.

Li Z, Lin F, Zhuo C, Deng G, Chen Z, Yin S, Gao Z, Piccioni M, Tsun A, Cai S, Zheng SG, Zhang Y, Li B.

J Biol Chem. 2014 Sep 26;289(39):26872-81. doi: 10.1074/jbc.M114.586651. Epub 2014 Aug 5.

15.

FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.

Itkin T, Ludin A, Gradus B, Gur-Cohen S, Kalinkovich A, Schajnovitz A, Ovadya Y, Kollet O, Canaani J, Shezen E, Coffin DJ, Enikolopov GN, Berg T, Piacibello W, Hornstein E, Lapidot T.

Blood. 2012 Aug 30;120(9):1843-55. doi: 10.1182/blood-2011-11-394692. Epub 2012 May 29.

16.

Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension.

Paulin R, Courboulin A, Meloche J, Mainguy V, Dumas de la Roque E, Saksouk N, Côté J, Provencher S, Sussman MA, Bonnet S.

Circulation. 2011 Mar 22;123(11):1205-15. doi: 10.1161/CIRCULATIONAHA.110.963314. Epub 2011 Mar 7.

17.

PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.

Zhang F, Beharry ZM, Harris TE, Lilly MB, Smith CD, Mahajan S, Kraft AS.

Cancer Biol Ther. 2009 May;8(9):846-53. Epub 2009 May 18.

PMID:
19276681
18.

Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase.

Kitayama H, Tsujimura T, Matsumura I, Oritani K, Ikeda H, Ishikawa J, Okabe M, Suzuki M, Yamamura K, Matsuzawa Y, Kitamura Y, Kanakura Y.

Blood. 1996 Aug 1;88(3):995-1004.

20.

RAGE-dependent activation of the oncoprotein Pim1 plays a critical role in systemic vascular remodeling processes.

Meloche J, Paulin R, Courboulin A, Lambert C, Barrier M, Bonnet P, Bisserier M, Roy M, Sussman MA, Agharazii M, Bonnet S.

Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2114-24. doi: 10.1161/ATVBAHA.111.230573. Epub 2011 Jun 16.

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