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Items: 1 to 20 of 86

1.

Fluorescent aminoglycosides reveal intracellular trafficking routes in mechanosensory hair cells.

Hailey DW, Esterberg R, Linbo TH, Rubel EW, Raible DW.

J Clin Invest. 2017 Feb 1;127(2):472-486. doi: 10.1172/JCI85052. Epub 2016 Dec 19.

2.

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.

Owens KN, Coffin AB, Hong LS, Bennett KO, Rubel EW, Raible DW.

Hear Res. 2009 Jul;253(1-2):32-41. doi: 10.1016/j.heares.2009.03.001. Epub 2009 Mar 11.

3.

Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.

Hailey DW, Roberts B, Owens KN, Stewart AK, Linbo T, Pujol R, Alper SL, Rubel EW, Raible DW.

PLoS Genet. 2012;8(10):e1002971. doi: 10.1371/journal.pgen.1002971. Epub 2012 Oct 11.

4.

Disruption of intracellular calcium regulation is integral to aminoglycoside-induced hair cell death.

Esterberg R, Hailey DW, Coffin AB, Raible DW, Rubel EW.

J Neurosci. 2013 Apr 24;33(17):7513-25. doi: 10.1523/JNEUROSCI.4559-12.2013.

5.

Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death.

Owens KN, Santos F, Roberts B, Linbo T, Coffin AB, Knisely AJ, Simon JA, Rubel EW, Raible DW.

PLoS Genet. 2008 Feb 29;4(2):e1000020. doi: 10.1371/journal.pgen.1000020.

6.

Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.

Vlasits AL, Simon JA, Raible DW, Rubel EW, Owens KN.

Hear Res. 2012 Dec;294(1-2):153-65. doi: 10.1016/j.heares.2012.08.002. Epub 2012 Aug 31.

7.

Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death.

Moon IS, So JH, Jung YM, Lee WS, Kim EY, Choi JH, Kim CH, Choi JY.

Hear Res. 2011 Dec;282(1-2):236-42. doi: 10.1016/j.heares.2011.07.007. Epub 2011 Jul 23.

PMID:
21810458
8.

Systemic aminoglycosides are trafficked via endolymph into cochlear hair cells.

Li H, Steyger PS.

Sci Rep. 2011;1:159. doi: 10.1038/srep00159. Epub 2011 Nov 16.

9.

Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line.

Coffin AB, Reinhart KE, Owens KN, Raible DW, Rubel EW.

Hear Res. 2009 Jul;253(1-2):42-51. doi: 10.1016/j.heares.2009.03.004. Epub 2009 Mar 12.

10.

Functional hair cell mechanotransducer channels are required for aminoglycoside ototoxicity.

Alharazneh A, Luk L, Huth M, Monfared A, Steyger PS, Cheng AG, Ricci AJ.

PLoS One. 2011;6(7):e22347. doi: 10.1371/journal.pone.0022347. Epub 2011 Jul 26.

11.

Trafficking of systemic fluorescent gentamicin into the cochlea and hair cells.

Wang Q, Steyger PS.

J Assoc Res Otolaryngol. 2009 Jun;10(2):205-19. doi: 10.1007/s10162-009-0160-4. Epub 2009 Mar 3.

12.

ER-mitochondrial calcium flow underlies vulnerability of mechanosensory hair cells to damage.

Esterberg R, Hailey DW, Rubel EW, Raible DW.

J Neurosci. 2014 Jul 16;34(29):9703-19. doi: 10.1523/JNEUROSCI.0281-14.2014.

13.

Sensory hair cell death and regeneration: two halves of the same equation.

Matsui JI, Cotanche DA.

Curr Opin Otolaryngol Head Neck Surg. 2004 Oct;12(5):418-25. Review.

PMID:
15377955
14.

Profiling drug-induced cell death pathways in the zebrafish lateral line.

Coffin AB, Williamson KL, Mamiya A, Raible DW, Rubel EW.

Apoptosis. 2013 Apr;18(4):393-408. doi: 10.1007/s10495-013-0816-8.

15.

Ultrastructural analysis of aminoglycoside-induced hair cell death in the zebrafish lateral line reveals an early mitochondrial response.

Owens KN, Cunningham DE, MacDonald G, Rubel EW, Raible DW, Pujol R.

J Comp Neurol. 2007 Jun 1;502(4):522-43.

PMID:
17394157
16.

Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo.

Matsui JI, Haque A, Huss D, Messana EP, Alosi JA, Roberson DW, Cotanche DA, Dickman JD, Warchol ME.

J Neurosci. 2003 Jul 9;23(14):6111-22.

17.

Mechanisms of hair cell death and protection.

Cheng AG, Cunningham LL, Rubel EW.

Curr Opin Otolaryngol Head Neck Surg. 2005 Dec;13(6):343-8. Review.

PMID:
16282762
18.

Competitive antagonism of fluorescent gentamicin uptake in the cochlea.

Wang Q, Kachelmeier A, Steyger PS.

Hear Res. 2010 Sep 1;268(1-2):250-9. doi: 10.1016/j.heares.2010.06.008. Epub 2010 Jun 16.

19.

Lateral line hair cell maturation is a determinant of aminoglycoside susceptibility in zebrafish (Danio rerio).

Santos F, MacDonald G, Rubel EW, Raible DW.

Hear Res. 2006 Mar;213(1-2):25-33. Epub 2006 Feb 3.

PMID:
16459035
20.

Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line.

Ou HC, Keating S, Wu P, Simon JA, Raible DW, Rubel EW.

J Assoc Res Otolaryngol. 2012 Dec;13(6):759-70. doi: 10.1007/s10162-012-0353-0. Epub 2012 Oct 10.

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