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Items: 1 to 20 of 227

1.

Chloroquine, an Endocytosis Blocking Agent, Inhibits Zika Virus Infection in Different Cell Models.

Delvecchio R, Higa LM, Pezzuto P, Valadão AL, Garcez PP, Monteiro FL, Loiola EC, Dias AA, Silva FJ, Aliota MT, Caine EA, Osorio JE, Bellio M, O'Connor DH, Rehen S, de Aguiar RS, Savarino A, Campanati L, Tanuri A.

Viruses. 2016 Nov 29;8(12). pii: E322.

2.

Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice.

Li C, Zhu X, Ji X, Quanquin N, Deng YQ, Tian M, Aliyari R, Zuo X, Yuan L, Afridi SK, Li XF, Jung JU, Nielsen-Saines K, Qin FX, Qin CF, Xu Z, Cheng G.

EBioMedicine. 2017 Oct;24:189-194. doi: 10.1016/j.ebiom.2017.09.034. Epub 2017 Sep 28.

3.

Ribavirin inhibits Zika virus (ZIKV) replication in vitro and suppresses viremia in ZIKV-infected STAT1-deficient mice.

Kamiyama N, Soma R, Hidano S, Watanabe K, Umekita H, Fukuda C, Noguchi K, Gendo Y, Ozaki T, Sonoda A, Sachi N, Runtuwene LR, Miura Y, Matsubara E, Tajima S, Takasaki T, Eshita Y, Kobayashi T.

Antiviral Res. 2017 Oct;146:1-11. doi: 10.1016/j.antiviral.2017.08.007. Epub 2017 Aug 14.

PMID:
28818572
4.

N-(2-(arylmethylimino)ethyl)-7-chloroquinolin-4-amine derivatives, synthesized by thermal and ultrasonic means, are endowed with anti-Zika virus activity.

Barbosa-Lima G, da Silveira Pinto LS, Kaiser CR, Wardell JL, De Freitas CS, Vieira YR, Marttorelli A, Cerbino Neto J, Bozza PT, Wardell SMSV, de Souza MVN, Souza TML.

Eur J Med Chem. 2017 Feb 15;127:434-441. doi: 10.1016/j.ejmech.2017.01.007. Epub 2017 Jan 6.

PMID:
28092859
5.

Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models.

Kim JA, Seong RK, Kumar M, Shin OS.

Viruses. 2018 Feb 9;10(2). pii: E72. doi: 10.3390/v10020072.

6.

Polysulfonate suramin inhibits Zika virus infection.

Tan CW, Sam IC, Chong WL, Lee VS, Chan YF.

Antiviral Res. 2017 Jul;143:186-194. doi: 10.1016/j.antiviral.2017.04.017. Epub 2017 Apr 27.

PMID:
28457855
7.

Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay.

Adcock RS, Chu YK, Golden JE, Chung DH.

Antiviral Res. 2017 Feb;138:47-56. doi: 10.1016/j.antiviral.2016.11.018. Epub 2016 Dec 3.

PMID:
27919709
8.

The FDA-approved drug sofosbuvir inhibits Zika virus infection.

Bullard-Feibelman KM, Govero J, Zhu Z, Salazar V, Veselinovic M, Diamond MS, Geiss BJ.

Antiviral Res. 2017 Jan;137:134-140. doi: 10.1016/j.antiviral.2016.11.023. Epub 2016 Nov 27.

9.

25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model.

Li C, Deng YQ, Wang S, Ma F, Aliyari R, Huang XY, Zhang NN, Watanabe M, Dong HL, Liu P, Li XF, Ye Q, Tian M, Hong S, Fan J, Zhao H, Li L, Vishlaghi N, Buth JE, Au C, Liu Y, Lu N, Du P, Qin FX, Zhang B, Gong D, Dai X, Sun R, Novitch BG, Xu Z, Qin CF, Cheng G.

Immunity. 2017 Mar 21;46(3):446-456. doi: 10.1016/j.immuni.2017.02.012. Epub 2017 Mar 14.

10.

The thiopurine nucleoside analogue 6-methylmercaptopurine riboside (6MMPr) effectively blocks Zika virus replication.

de Carvalho OV, Félix DM, de Mendonça LR, de Araújo CMCS, de Oliveira Franca RF, Cordeiro MT, Silva Júnior A, Pena LJ.

Int J Antimicrob Agents. 2017 Dec;50(6):718-725. doi: 10.1016/j.ijantimicag.2017.08.016. Epub 2017 Aug 10.

PMID:
28803932
11.

Nuclear import inhibitor N-(4-hydroxyphenyl) retinamide targets Zika virus (ZIKV) nonstructural protein 5 to inhibit ZIKV infection.

Wang C, Yang SNY, Smith K, Forwood JK, Jans DA.

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1555-1559. doi: 10.1016/j.bbrc.2017.10.016. Epub 2017 Oct 4.

PMID:
28988109
12.

Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens.

Tong X, Smith J, Bukreyeva N, Koma T, Manning JT, Kalkeri R, Kwong AD, Paessler S.

Antiviral Res. 2018 Jan;149:34-40. doi: 10.1016/j.antiviral.2017.11.004. Epub 2017 Nov 8.

PMID:
29126899
13.

The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model.

Zmurko J, Marques RE, Schols D, Verbeken E, Kaptein SJ, Neyts J.

PLoS Negl Trop Dis. 2016 May 10;10(5):e0004695. doi: 10.1371/journal.pntd.0004695. eCollection 2016 May.

14.

Zika Virus Induces Autophagy in Human Umbilical Vein Endothelial Cells.

Peng H, Liu B, Yves TD, He Y, Wang S, Tang H, Ren H, Zhao P, Qi Z, Qin Z.

Viruses. 2018 May 15;10(5). pii: E259. doi: 10.3390/v10050259.

15.

Antiviral activity of N-(4-hydroxyphenyl) retinamide (4-HPR) against Zika virus.

Pitts JD, Li PC, de Wispelaere M, Yang PL.

Antiviral Res. 2017 Nov;147:124-130. doi: 10.1016/j.antiviral.2017.10.014. Epub 2017 Oct 16.

16.

The green tea molecule EGCG inhibits Zika virus entry.

Carneiro BM, Batista MN, Braga ACS, Nogueira ML, Rahal P.

Virology. 2016 Sep;496:215-218. doi: 10.1016/j.virol.2016.06.012. Epub 2016 Jun 23.

17.

Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action.

Chen J, Liang Y, Yi P, Xu L, Hawkins HK, Rossi SL, Soong L, Cai J, Menon R, Sun J.

Cell Rep. 2017 Nov 7;21(6):1588-1599. doi: 10.1016/j.celrep.2017.10.059.

18.

An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors.

Shan C, Xie X, Muruato AE, Rossi SL, Roundy CM, Azar SR, Yang Y, Tesh RB, Bourne N, Barrett AD, Vasilakis N, Weaver SC, Shi PY.

Cell Host Microbe. 2016 Jun 8;19(6):891-900. doi: 10.1016/j.chom.2016.05.004. Epub 2016 May 16.

19.

Zika virus cell tropism in the developing human brain and inhibition by azithromycin.

Retallack H, Di Lullo E, Arias C, Knopp KA, Laurie MT, Sandoval-Espinosa C, Mancia Leon WR, Krencik R, Ullian EM, Spatazza J, Pollen AA, Mandel-Brehm C, Nowakowski TJ, Kriegstein AR, DeRisi JL.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14408-14413. Epub 2016 Nov 29.

20.

Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals.

Lanko K, Eggermont K, Patel A, Kaptein S, Delang L, Verfaillie CM, Neyts J.

Antiviral Res. 2017 Sep;145:82-86. doi: 10.1016/j.antiviral.2017.07.010. Epub 2017 Jul 20.

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