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Items: 1 to 20 of 110


In-vitro influence of mycophenolate mofetil (MMF) and Ciclosporin A (CsA) on cytokine induced killer (CIK) cell immunotherapy.

Bremm M, Huenecke S, Zimmermann O, Pfirrmann V, Quaiser A, Bonig H, Soerensen J, Klingebiel T, Rettinger E, Bader P, Cappel C.

J Transl Med. 2016 Sep 13;14:264. doi: 10.1186/s12967-016-1024-4.


Mycophenolic acid inhibits natural killer cell proliferation and cytotoxic function: a possible disadvantage of including mycophenolate mofetil in the graft-versus-host disease prophylaxis regimen.

Ohata K, Espinoza JL, Lu X, Kondo Y, Nakao S.

Biol Blood Marrow Transplant. 2011 Feb;17(2):205-13. doi: 10.1016/j.bbmt.2010.08.014. Epub 2010 Aug 22.


Human interferon-alpha increases the cytotoxic effect of CD56(+) cord blood-derived cytokine-induced killer cells on human B-acute lymphoblastic leukemia cell lines.

Durrieu L, Gregoire-Gauthier J, Dieng MM, Fontaine F, le Deist F, Haddad E.

Cytotherapy. 2012 Nov;14(10):1245-57. doi: 10.3109/14653249.2012.714864. Epub 2012 Sep 14.


[Thymoglobulin efficiently expands cytokine-induced killer cells in a clinical-grade culture protocol].

Chen W, Lin D, Jiang Z, Yang Z, Song S, Zhou J, Zhou L, Sun Y, Yu H, Ma D.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Jul;30(7):681-5, 690. Chinese.


The dual-functional capability of cytokine-induced killer cells and application in tumor immunology.

Zhang Q, Liu XY, Zhang T, Zhang XF, Zhao L, Long F, Liu ZK, Wang EH.

Hum Immunol. 2015 May;76(5):385-91. doi: 10.1016/j.humimm.2014.09.021. Epub 2014 Oct 8. Review.


Differential effects of mycophenolate mofetil and cyclosporine A on peripheral blood and cord blood natural killer cells activated with interleukin-2.

Derniame S, Perazzo J, Lee F, Domogala A, Escobedo-Cousin M, Alnabhan R, Luevano M, Pedroza-Pacheco I, Cooper N, Madrigal A, Saudemont A.

Cytotherapy. 2014 Oct;16(10):1409-18. doi: 10.1016/j.jcyt.2014.05.010. Epub 2014 Jun 23.


Cytotoxic potential of IL-15-activated cytokine-induced killer cells against human neuroblastoma cells.

Cappel C, Huenecke S, Suemmerer A, Erben S, Rettinger E, Pfirrmann V, Heinze A, Zimmermann O, Klingebiel T, Ullrich E, Bader P, Bremm M.

Pediatr Blood Cancer. 2016 Dec;63(12):2230-2239. doi: 10.1002/pbc.26147. Epub 2016 Jul 19.


Cytomegalovirus-specific cytokine-induced killer cells: concurrent targeting of leukemia and cytomegalovirus.

Pfirrmann V, Oelsner S, Rettinger E, Huenecke S, Bonig H, Merker M, Wels WS, Cinatl J, Schubert R, Klingebiel T, Bader P.

Cytotherapy. 2015 Aug;17(8):1139-51. doi: 10.1016/j.jcyt.2015.04.011. Epub 2015 Jun 10.


Rapamycin and MPA, but not CsA, impair human NK cell cytotoxicity due to differential effects on NK cell phenotype.

Eissens DN, Van Der Meer A, Van Cranenbroek B, Preijers FW, Joosten I.

Am J Transplant. 2010 Sep;10(9):1981-90. doi: 10.1111/j.1600-6143.2010.03242.x.


Natural Killer Cell Activating Receptor NKG2D Is Involved in the Immunosuppressive Effects of Mycophenolate Mofetil and Hepatitis B Virus Infection.

Dong S, Geng L, Shen MD, Zheng SS.

Am J Med Sci. 2015 May;349(5):432-7. doi: 10.1097/MAJ.0000000000000442.


Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation.

Laport GG, Sheehan K, Baker J, Armstrong R, Wong RM, Lowsky R, Johnston LJ, Shizuru JA, Miklos D, Arai S, Benjamin JE, Weng WK, Negrin RS.

Biol Blood Marrow Transplant. 2011 Nov;17(11):1679-87. doi: 10.1016/j.bbmt.2011.05.012. Epub 2011 May 25.


Immunomagnetic selection or irradiation eliminates alloreactive cells but also reduces anti-tumor potential of cytokine-induced killer cells: implications for unmanipulated cytokine-induced killer cell infusion.

Rettinger E, Kreyenberg H, Merker M, Kuçi S, Willasch A, Bug G, Ullrich E, Wels WS, Bonig H, Klingebiel T, Bader P.

Cytotherapy. 2014 Jun;16(6):835-44. doi: 10.1016/j.jcyt.2014.01.003. Epub 2014 Feb 28.


Thymoglobulin, interferon-γ and interleukin-2 efficiently expand cytokine-induced killer (CIK) cells in clinical-grade cultures.

Bonanno G, Iudicone P, Mariotti A, Procoli A, Pandolfi A, Fioravanti D, Corallo M, Perillo A, Scambia G, Pierelli L, Rutella S.

J Transl Med. 2010 Dec 7;8:129. doi: 10.1186/1479-5876-8-129.


Interleukin-2-stimulated natural killer cells are less susceptible to mycophenolate mofetil than non-activated NK cells: possible consequences for immunotherapy.

Brehm C, Huenecke S, Esser R, Kloess S, Quaiser A, Betz S, Zimmermann O, Soerensen J, Passweg JR, Klingebiel T, Schwabe D, Bader P, Koehl U.

Cancer Immunol Immunother. 2014 Aug;63(8):821-33. doi: 10.1007/s00262-014-1556-5. Epub 2014 May 8.


Dual-functional capability of CD3+CD56+ CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity.

Pievani A, Borleri G, Pende D, Moretta L, Rambaldi A, Golay J, Introna M.

Blood. 2011 Sep 22;118(12):3301-10. doi: 10.1182/blood-2011-02-336321. Epub 2011 Aug 5.


Gemcitabine treatment enhanced the anti-tumor effect of cytokine induced killer cells by depletion of CD4+CD25bri regulatory T cells.

Zhao P, Zhu D, Zhang Z, Han B, Gao D, Wei X, Xie X, Li C, Sun W, Wang Q, Guo Q.

Immunol Lett. 2017 Jan;181:36-44. doi: 10.1016/j.imlet.2016.11.009. Epub 2016 Nov 17.


Coculturing dendritic cells with zoledronate acid efficiently enhance the anti-tumor effects of cytokine-induced killer cells.

Su X, Zhang L, Jin L, Ye J, Guan Z, Chen R.

J Clin Immunol. 2010 Sep;30(5):766-74. doi: 10.1007/s10875-010-9434-1. Epub 2010 Jun 15.


Chimeric antigen receptor-engineered cytokine-induced killer cells overcome treatment resistance of pre-B-cell acute lymphoblastic leukemia and enhance survival.

Oelsner S, Wagner J, Friede ME, Pfirrmann V, Genßler S, Rettinger E, Buchholz CJ, Pfeifer H, Schubert R, Ottmann OG, Ullrich E, Bader P, Wels WS.

Int J Cancer. 2016 Oct 15;139(8):1799-809. doi: 10.1002/ijc.30217. Epub 2016 Jun 11.


Interleukin-6 inhibits regulatory T cells and improves the proliferation and cytotoxic activity of cytokine-induced killer cells.

Lin G, Wang J, Lao X, Wang J, Li L, Li S, Zhang J, Dong Y, Chang AE, Li Q, Li S.

J Immunother. 2012 May;35(4):337-43. doi: 10.1097/CJI.0b013e318255ada3.


Immune checkpoint inhibitors enhance cytotoxicity of cytokine-induced killer cells against human myeloid leukaemic blasts.

Poh SL, Linn YC.

Cancer Immunol Immunother. 2016 May;65(5):525-36. doi: 10.1007/s00262-016-1815-8. Epub 2016 Mar 10.


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