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Items: 1 to 20 of 129


Atomic resolution structure determination by the cryo-EM method MicroED.

Liu S, Hattne J, Reyes FE, Sanchez-Martinez S, Jason de la Cruz M, Shi D, Gonen T.

Protein Sci. 2017 Jan;26(1):8-15. doi: 10.1002/pro.2989. Epub 2016 Aug 19. Review.


High-Resolution Macromolecular Structure Determination by MicroED, a cryo-EM Method.

Rodriguez JA, Gonen T.

Methods Enzymol. 2016;579:369-92. doi: 10.1016/bs.mie.2016.04.017. Epub 2016 Jun 16. Review.


MicroED opens a new era for biological structure determination.

Nannenga BL, Gonen T.

Curr Opin Struct Biol. 2016 Oct;40:128-135. doi: 10.1016/ Epub 2016 Oct 1. Review.


MicroED data collection and processing.

Hattne J, Reyes FE, Nannenga BL, Shi D, de la Cruz MJ, Leslie AG, Gonen T.

Acta Crystallogr A Found Adv. 2015 Jul;71(Pt 4):353-60. doi: 10.1107/S2053273315010669. Epub 2015 Jul 1.


Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.

de la Cruz MJ, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SK, Hinck CS, Hinck AP, Calero G, Eisenberg D, Gonen T.

Nat Methods. 2017 Feb 13;14(4):399-402. doi: 10.1038/nmeth.4178.


Analysis of Global and Site-Specific Radiation Damage in Cryo-EM.

Hattne J, Shi D, Glynn C, Zee CT, Gallagher-Jones M, Martynowycz MW, Rodriguez JA, Gonen T.

Structure. 2018 May 1;26(5):759-766.e4. doi: 10.1016/j.str.2018.03.021. Epub 2018 Apr 26.


Taking the measure of MicroED.

Rodriguez JA, Eisenberg DS, Gonen T.

Curr Opin Struct Biol. 2017 Oct;46:79-86. doi: 10.1016/ Epub 2017 Jun 22. Review.


Protein structure determination by MicroED.

Nannenga BL, Gonen T.

Curr Opin Struct Biol. 2014 Aug;27:24-31. doi: 10.1016/ Epub 2014 Apr 5. Review.


New approaches towards the understanding of integral membrane proteins: A structural perspective on G protein-coupled receptors.

Grisshammer R.

Protein Sci. 2017 Aug;26(8):1493-1504. doi: 10.1002/pro.3200. Epub 2017 Jun 7. Review.


In situ protein micro-crystal fabrication by cryo-FIB for electron diffraction.

Li X, Zhang S, Zhang J, Sun F.

Biophys Rep. 2018;4(6):339-347. doi: 10.1007/s41048-018-0075-x. Epub 2018 Nov 14.


Structure of catalase determined by MicroED.

Nannenga BL, Shi D, Hattne J, Reyes FE, Gonen T.

Elife. 2014 Oct 10;3:e03600. doi: 10.7554/eLife.03600.


From electron crystallography of 2D crystals to MicroED of 3D crystals.

Martynowycz MW, Gonen T.

Curr Opin Colloid Interface Sci. 2018 Mar;34:9-16. doi: 10.1016/j.cocis.2018.01.010. Epub 2018 Jan 31.


A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals.

Xu H, Lebrette H, Yang T, Srinivas V, Hovmöller S, Högbom M, Zou X.

Structure. 2018 Apr 3;26(4):667-675.e3. doi: 10.1016/j.str.2018.02.015. Epub 2018 Mar 15.


Transmission electron microscopy for the evaluation and optimization of crystal growth.

Stevenson HP, Lin G, Barnes CO, Sutkeviciute I, Krzysiak T, Weiss SC, Reynolds S, Wu Y, Nagarajan V, Makhov AM, Lawrence R, Lamm E, Clark L, Gardella TJ, Hogue BG, Ogata CM, Ahn J, Gronenborn AM, Conway JF, Vilardaga JP, Cohen AE, Calero G.

Acta Crystallogr D Struct Biol. 2016 May;72(Pt 5):603-15. doi: 10.1107/S2059798316001546. Epub 2016 Apr 26.


MicroED: a versatile cryoEM method for structure determination.

Nannenga BL, Gonen T.

Emerg Top Life Sci. 2018 Apr 20;2(1):1-8. doi: 10.1042/ETLS20170082. Epub 2018 Feb 6.


The collection of MicroED data for macromolecular crystallography.

Shi D, Nannenga BL, de la Cruz MJ, Liu J, Sawtelle S, Calero G, Reyes FE, Hattne J, Gonen T.

Nat Protoc. 2016 May;11(5):895-904. doi: 10.1038/nprot.2016.046. Epub 2016 Apr 14.


Three-dimensional electron crystallography of protein microcrystals.

Shi D, Nannenga BL, Iadanza MG, Gonen T.

Elife. 2013 Nov 19;2:e01345. doi: 10.7554/eLife.01345.


How cryo-electron microscopy and X-ray crystallography complement each other.

Wang HW, Wang JW.

Protein Sci. 2017 Jan;26(1):32-39. doi: 10.1002/pro.3022. Epub 2016 Sep 7. Review.


The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination.

Jones CG, Martynowycz MW, Hattne J, Fulton TJ, Stoltz BM, Rodriguez JA, Nelson HM, Gonen T.

ACS Cent Sci. 2018 Nov 28;4(11):1587-1592. doi: 10.1021/acscentsci.8b00760. Epub 2018 Nov 2.


Collection of Continuous Rotation MicroED Data from Ion Beam-Milled Crystals of Any Size.

Martynowycz MW, Zhao W, Hattne J, Jensen GJ, Gonen T.

Structure. 2019 Mar 5;27(3):545-548.e2. doi: 10.1016/j.str.2018.12.003. Epub 2019 Jan 17.


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