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Items: 1 to 20 of 152

1.

Genotype-phenotype correlation of CTNNB1 mutations reveals different ß-catenin activity associated with liver tumor progression.

Rebouissou S, Franconi A, Calderaro J, Letouzé E, Imbeaud S, Pilati C, Nault JC, Couchy G, Laurent A, Balabaud C, Bioulac-Sage P, Zucman-Rossi J.

Hepatology. 2016 Dec;64(6):2047-2061. doi: 10.1002/hep.28638. Epub 2016 Jun 11.

PMID:
27177928
2.

Hepatocellular Adenomas: Morphology and Genomics.

Bioulac-Sage P, Sempoux C, Balabaud C.

Gastroenterol Clin North Am. 2017 Jun;46(2):253-272. doi: 10.1016/j.gtc.2017.01.003. Review.

PMID:
28506364
3.

Correlation of exon 3 β-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma.

Hale G, Liu X, Hu J, Xu Z, Che L, Solomon D, Tsokos C, Shafizadeh N, Chen X, Gill R, Kakar S.

Mod Pathol. 2016 Nov;29(11):1370-1380. doi: 10.1038/modpathol.2016.122. Epub 2016 Jul 29.

4.

Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.

Nault JC, Couchy G, Balabaud C, Morcrette G, Caruso S, Blanc JF, Bacq Y, Calderaro J, Paradis V, Ramos J, Scoazec JY, Gnemmi V, Sturm N, Guettier C, Fabre M, Savier E, Chiche L, Labrune P, Selves J, Wendum D, Pilati C, Laurent A, De Muret A, Le Bail B, Rebouissou S, Imbeaud S; GENTHEP Investigators, Bioulac-Sage P, Letouzé E, Zucman-Rossi J.

Gastroenterology. 2017 Mar;152(4):880-894.e6. doi: 10.1053/j.gastro.2016.11.042. Epub 2016 Dec 7.

5.

ALDH3A1 is overexpressed in a subset of hepatocellular carcinoma characterised by activation of the Wnt/ß-catenin pathway.

Calderaro J, Nault JC, Bioulac-Sage P, Laurent A, Blanc JF, Decaens T, Zucman-Rossi J.

Virchows Arch. 2014 Jan;464(1):53-60. doi: 10.1007/s00428-013-1515-0. Epub 2013 Nov 26.

PMID:
24276407
6.

Genotype-phenotype correlation in hepatocellular adenoma: new classification and relationship with HCC.

Zucman-Rossi J, Jeannot E, Nhieu JT, Scoazec JY, Guettier C, Rebouissou S, Bacq Y, Leteurtre E, Paradis V, Michalak S, Wendum D, Chiche L, Fabre M, Mellottee L, Laurent C, Partensky C, Castaing D, Zafrani ES, Laurent-Puig P, Balabaud C, Bioulac-Sage P.

Hepatology. 2006 Mar;43(3):515-24.

PMID:
16496320
7.

Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.

Cieply B, Zeng G, Proverbs-Singh T, Geller DA, Monga SP.

Hepatology. 2009 Mar;49(3):821-31. doi: 10.1002/hep.22695.

8.

Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma.

Ding SL, Yang ZW, Wang J, Zhang XL, Chen XM, Lu FM.

World J Gastroenterol. 2015 May 28;21(20):6317-28. doi: 10.3748/wjg.v21.i20.6317. Review.

9.

Focal β-catenin mutation identified on formalin-fixed and paraffin-embedded inflammatory hepatocellular adenomas.

Saldarriaga J, Bisig B, Couchy G, Castain C, Zucman-Rossi J, Balabaud C, Sempoux C, Bioulac-Sage P.

Histopathology. 2017 Dec;71(6):989-993. doi: 10.1111/his.13283. Epub 2017 Oct 6.

PMID:
28618047
10.

Recent advances in cytogenetics and molecular biology of adult hepatocellular tumors: implications for imaging and management.

Shanbhogue AK, Prasad SR, Takahashi N, Vikram R, Sahani DV.

Radiology. 2011 Mar;258(3):673-93. doi: 10.1148/radiol.10100376. Review.

PMID:
21339346
11.

RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours.

Longerich T, Endris V, Neumann O, Rempel E, Kirchner M, Abadi Z, Uhrig S, Kriegsmann M, Weiss KH, Breuhahn K, Mehrabi A, Weber TF, Wilkens L, Straub BK, Rosenwald A, Schulze F, Brors B, Froehling S, Pellegrino R, Budczies J, Schirmacher P, Stenzinger A.

Gut. 2019 Feb 2. pii: gutjnl-2018-317632. doi: 10.1136/gutjnl-2018-317632. [Epub ahead of print]

PMID:
30901310
12.

GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation.

Nault JC, Fabre M, Couchy G, Pilati C, Jeannot E, Tran Van Nhieu J, Saint-Paul MC, De Muret A, Redon MJ, Buffet C, Salenave S, Balabaud C, Prevot S, Labrune P, Bioulac-Sage P, Scoazec JY, Chanson P, Zucman-Rossi J.

J Hepatol. 2012 Jan;56(1):184-91. doi: 10.1016/j.jhep.2011.07.018. Epub 2011 Aug 9.

PMID:
21835143
13.

Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.

Sempoux C, Bisig B, Couchy G, Balabaud C, Zucman-Rossi J, Bioulac-Sage P.

Hum Pathol. 2017 Apr;62:122-125. doi: 10.1016/j.humpath.2016.10.004. Epub 2016 Oct 28.

PMID:
27984126
14.

Germline and somatic DICER1 mutations in familial and sporadic liver tumors.

Caruso S, Calderaro J, Letouzé E, Nault JC, Couchy G, Boulai A, Luciani A, Zafrani ES, Bioulac-Sage P, Seror O, Imbeaud S, Zucman-Rossi J.

J Hepatol. 2017 Apr;66(4):734-742. doi: 10.1016/j.jhep.2016.12.010. Epub 2016 Dec 22.

PMID:
28012864
15.

Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin.

Tao J, Xu E, Zhao Y, Singh S, Li X, Couchy G, Chen X, Zucman-Rossi J, Chikina M, Monga SP.

Hepatology. 2016 Nov;64(5):1587-1605. doi: 10.1002/hep.28601. Epub 2016 May 28.

16.

Hepatocellular adenoma classification: a comparative evaluation of immunohistochemistry and targeted mutational analysis.

Margolskee E, Bao F, de Gonzalez AK, Moreira RK, Lagana S, Sireci AN, Sepulveda AR, Remotti H, Lefkowitch JH, Salomao M.

Diagn Pathol. 2016 Mar 9;11:27. doi: 10.1186/s13000-016-0475-5.

17.

CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1.

Devereux TR, Stern MC, Flake GP, Yu MC, Zhang ZQ, London SJ, Taylor JA.

Mol Carcinog. 2001 Jun;31(2):68-73.

PMID:
11429783
18.

Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma.

Pezzuto F, Izzo F, Buonaguro L, Annunziata C, Tatangelo F, Botti G, Buonaguro FM, Tornesello ML.

Oncotarget. 2016 Aug 23;7(34):54253-54262. doi: 10.18632/oncotarget.9801.

19.

Multiple β-catenin mutations in hepatocellular lesions arising in Abernethy malformation.

Sorkin T, Strautnieks S, Foskett P, Peddu P, Thompson RJ, Heaton N, Quaglia A.

Hum Pathol. 2016 Jul;53:153-8. doi: 10.1016/j.humpath.2016.02.025. Epub 2016 Mar 30.

PMID:
27038679
20.

Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors.

Yamaoka H, Ohtsu K, Sueda T, Yokoyama T, Hiyama E.

Oncol Rep. 2006 Mar;15(3):551-6.

PMID:
16465411

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