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Items: 1 to 20 of 109

1.

Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies.

Matsuba R, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

PLoS One. 2016 Apr 26;11(4):e0154093. doi: 10.1371/journal.pone.0154093. eCollection 2016.

2.

The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes.

Harder MN, Appel EV, Grarup N, Gjesing AP, Ahluwalia TS, Jørgensen T, Christensen C, Brandslund I, Linneberg A, Sørensen TI, Pedersen O, Hansen T.

PLoS One. 2015 Mar 23;10(3):e0120890. doi: 10.1371/journal.pone.0120890. eCollection 2015.

3.

A single nucleotide polymorphism within DUSP9 is associated with susceptibility to type 2 diabetes in a Japanese population.

Fukuda H, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

PLoS One. 2012;7(9):e46263. doi: 10.1371/journal.pone.0046263. Epub 2012 Sep 27.

4.

Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes.

Matsuba R, Sakai K, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

PLoS One. 2015 May 7;10(5):e0126363. doi: 10.1371/journal.pone.0126363. eCollection 2015.

5.

Replication study for the association of 9 East Asian GWAS-derived loci with susceptibility to type 2 diabetes in a Japanese population.

Sakai K, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

PLoS One. 2013 Sep 25;8(9):e76317. doi: 10.1371/journal.pone.0076317. eCollection 2013.

6.

Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.

Nair AK, Muller YL, McLean NA, Abdussamad M, Piaggi P, Kobes S, Weil EJ, Curtis JM, Nelson RG, Knowler WC, Hanson RL, Baier LJ.

Diabetologia. 2014 Nov;57(11):2334-8. doi: 10.1007/s00125-014-3351-4. Epub 2014 Aug 12.

7.

Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes.

Maeda S, Imamura M, Kurashige M, Araki S, Suzuki D, Babazono T, Uzu T, Umezono T, Toyoda M, Kawai K, Imanishi M, Hanaoka K, Maegawa H, Uchigata Y, Hosoya T.

Clin Exp Nephrol. 2013 Dec;17(6):866-71. doi: 10.1007/s10157-013-0797-5. Epub 2013 Mar 30.

PMID:
23543049
8.

Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals.

Takeuchi F, Yamamoto K, Katsuya T, Nabika T, Sugiyama T, Fujioka A, Isono M, Ohnaka K, Fujisawa T, Nakashima E, Ikegami H, Nakamura J, Yamori Y, Yamaguchi S, Kobayashi S, Ogihara T, Takayanagi R, Kato N.

Diabetologia. 2011 Jun;54(6):1350-9. doi: 10.1007/s00125-011-2086-8. Epub 2011 Mar 3.

PMID:
21369819
9.

Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese.

Ohshige T, Iwata M, Omori S, Tanaka Y, Hirose H, Kaku K, Maegawa H, Watada H, Kashiwagi A, Kawamori R, Tobe K, Kadowaki T, Nakamura Y, Maeda S.

PLoS One. 2011;6(10):e26911. doi: 10.1371/journal.pone.0026911. Epub 2011 Oct 26.

10.

Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals.

Omori S, Tanaka Y, Horikoshi M, Takahashi A, Hara K, Hirose H, Kashiwagi A, Kaku K, Kawamori R, Kadowaki T, Nakamura Y, Maeda S.

Diabetologia. 2009 Aug;52(8):1554-60. doi: 10.1007/s00125-009-1397-5. Epub 2009 May 20.

PMID:
19455301
11.

Replication study for the association of a single-nucleotide polymorphism, rs3746876, within KCNJ15, with susceptibility to type 2 diabetes in a Japanese population.

Fukuda H, Imamura M, Tanaka Y, Iwata M, Hirose H, Kaku K, Maegawa H, Watada H, Tobe K, Kashiwagi A, Kawamori R, Maeda S.

J Hum Genet. 2013 Jul;58(7):490-3. doi: 10.1038/jhg.2013.28. Epub 2013 Apr 18.

PMID:
23595124
12.

A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations.

Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, Morizono T, Takahashi A, Horikoshi M, Nakamura M, Fujita H, Tsunoda T, Kubo M, Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Ohshige T, Omori S, Iwata M, Hirose H, Kaku K, Ito C, Tanaka Y, Tobe K, Kashiwagi A, Kawamori R, Kasuga M, Kamatani N; Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Nakamura Y, Kadowaki T.

Hum Mol Genet. 2012 Jul 1;21(13):3042-9. doi: 10.1093/hmg/dds113. Epub 2012 Mar 28.

PMID:
22456796
13.

Assessing the clinical utility of a genetic risk score constructed using 49 susceptibility alleles for type 2 diabetes in a Japanese population.

Imamura M, Shigemizu D, Tsunoda T, Iwata M, Maegawa H, Watada H, Hirose H, Tanaka Y, Tobe K, Kaku K, Kashiwagi A, Kawamori R, Maeda S.

J Clin Endocrinol Metab. 2013 Oct;98(10):E1667-73. doi: 10.1210/jc.2013-1642. Epub 2013 Aug 16.

PMID:
23956346
14.

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.

Suzuki K, Akiyama M, Ishigaki K, Kanai M, Hosoe J, Shojima N, Hozawa A, Kadota A, Kuriki K, Naito M, Tanno K, Ishigaki Y, Hirata M, Matsuda K, Iwata N, Ikeda M, Sawada N, Yamaji T, Iwasaki M, Ikegawa S, Maeda S, Murakami Y, Wakai K, Tsugane S, Sasaki M, Yamamoto M, Okada Y, Kubo M, Kamatani Y, Horikoshi M, Yamauchi T, Kadowaki T.

Nat Genet. 2019 Mar;51(3):379-386. doi: 10.1038/s41588-018-0332-4. Epub 2019 Feb 4.

PMID:
30718926
15.

Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study.

Chen Z, Pereira MA, Seielstad M, Koh WP, Tai ES, Teo YY, Liu J, Hsu C, Wang R, Odegaard AO, Thyagarajan B, Koratkar R, Yuan JM, Gross MD, Stram DO.

PLoS One. 2014 Feb 10;9(2):e87762. doi: 10.1371/journal.pone.0087762. eCollection 2014.

16.

The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study.

Yamakawa-Kobayashi K, Natsume M, Aoki S, Nakano S, Inamori T, Kasezawa N, Goda T.

BMC Med Genet. 2012 Feb 24;13:11. doi: 10.1186/1471-2350-13-11.

17.

Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore.

Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES.

J Clin Endocrinol Metab. 2010 Jan;95(1):390-7. doi: 10.1210/jc.2009-0688. Epub 2009 Nov 5.

PMID:
19892838
18.

Genetic variants at CDC123/CAMK1D and SPRY2 are associated with susceptibility to type 2 diabetes in the Japanese population.

Imamura M, Iwata M, Maegawa H, Watada H, Hirose H, Tanaka Y, Tobe K, Kaku K, Kashiwagi A, Kawamori R, Nakamura Y, Maeda S.

Diabetologia. 2011 Dec;54(12):3071-7. doi: 10.1007/s00125-011-2293-3. Epub 2011 Sep 10.

PMID:
21909839
19.

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.

Imamura M, Takahashi A, Yamauchi T, Hara K, Yasuda K, Grarup N, Zhao W, Wang X, Huerta-Chagoya A, Hu C, Moon S, Long J, Kwak SH, Rasheed A, Saxena R, Ma RC, Okada Y, Iwata M, Hosoe J, Shojima N, Iwasaki M, Fujita H, Suzuki K, Danesh J, Jørgensen T, Jørgensen ME, Witte DR, Brandslund I, Christensen C, Hansen T, Mercader JM, Flannick J, Moreno-Macías H, Burtt NP, Zhang R, Kim YJ, Zheng W, Singh JR, Tam CH, Hirose H, Maegawa H, Ito C, Kaku K, Watada H, Tanaka Y, Tobe K, Kawamori R, Kubo M, Cho YS, Chan JC, Sanghera D, Frossard P, Park KS, Shu XO, Kim BJ, Florez JC, Tusié-Luna T, Jia W, Tai ES, Pedersen O, Saleheen D, Maeda S, Kadowaki T.

Nat Commun. 2016 Jan 28;7:10531. doi: 10.1038/ncomms10531.

20.

Validation of Type 2 Diabetes Risk Variants Identified by Genome-Wide Association Studies in Northern Han Chinese.

Rao P, Zhou Y, Ge SQ, Wang AX, Yu XW, Alzain MA, Veronica AK, Qiu J, Song MS, Zhang J, Wang H, Fang HH, Gao Q, Wang YX, Wang W.

Int J Environ Res Public Health. 2016 Aug 30;13(9). pii: E863. doi: 10.3390/ijerph13090863.

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