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Items: 1 to 20 of 89


Nuclear fallout provides a new link between aPKC and polarized cell trafficking.

Calero-Cuenca FJ, Espinosa-Vázquez JM, Reina-Campos M, Díaz-Meco MT, Moscat J, Sotillos S.

BMC Biol. 2016 Apr 18;14:32. doi: 10.1186/s12915-016-0253-6.


Nuf and Rip11 requirement for polarity determinant recycling during Drosophila development.

Calero-Cuenca FJ, Sotillos S.

Small GTPases. 2018 Jul 4;9(4):352-359. doi: 10.1080/21541248.2016.1235386. Epub 2016 Nov 1.


Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11.

Riggs B, Rothwell W, Mische S, Hickson GR, Matheson J, Hays TS, Gould GW, Sullivan W.

J Cell Biol. 2003 Oct 13;163(1):143-54. Epub 2003 Oct 6.


The concentration of Nuf, a Rab11 effector, at the microtubule-organizing center is cell cycle regulated, dynein-dependent, and coincides with furrow formation.

Riggs B, Fasulo B, Royou A, Mische S, Cao J, Hays TS, Sullivan W.

Mol Biol Cell. 2007 Sep;18(9):3313-22. Epub 2007 Jun 20.


aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

Atwood SX, Prehoda KE.

Curr Biol. 2009 May 12;19(9):723-9. doi: 10.1016/j.cub.2009.03.056. Epub 2009 Apr 16.


Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC.

Atwood SX, Chabu C, Penkert RR, Doe CQ, Prehoda KE.

J Cell Sci. 2007 Sep 15;120(Pt 18):3200-6. Epub 2007 Aug 28.


The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye.

Djiane A, Yogev S, Mlodzik M.

Cell. 2005 May 20;121(4):621-631. doi: 10.1016/j.cell.2005.03.014.


Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

Grzeschik NA, Parsons LM, Allott ML, Harvey KF, Richardson HE.

Curr Biol. 2010 Apr 13;20(7):573-81. doi: 10.1016/j.cub.2010.01.055. Epub 2010 Apr 1.


Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions.

Ogawa H, Ohta N, Moon W, Matsuzaki F.

J Cell Sci. 2009 Sep 15;122(Pt 18):3242-9. doi: 10.1242/jcs.050955. Epub 2009 Aug 18.


aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.

Smith CA, Lau KM, Rahmani Z, Dho SE, Brothers G, She YM, Berry DM, Bonneil E, Thibault P, Schweisguth F, Le Borgne R, McGlade CJ.

EMBO J. 2007 Jan 24;26(2):468-80. Epub 2007 Jan 4.


Polo kinase mediates the phosphorylation and cellular localization of Nuf/FIP3, a Rab11 effector.

Brose L, Crest J, Tao L, Sullivan W.

Mol Biol Cell. 2017 Jun 1;28(11):1435-1443. doi: 10.1091/mbc.E16-04-0236. Epub 2017 Apr 5.


Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.

Leong GR, Goulding KR, Amin N, Richardson HE, Brumby AM.

BMC Biol. 2009 Sep 24;7:62. doi: 10.1186/1741-7007-7-62.


Kinase-activity-independent functions of atypical protein kinase C in Drosophila.

Kim S, Gailite I, Moussian B, Luschnig S, Goette M, Fricke K, Honemann-Capito M, Grubmüller H, Wodarz A.

J Cell Sci. 2009 Oct 15;122(Pt 20):3759-71. doi: 10.1242/jcs.052514. Epub 2009 Sep 29.


A novel function for the PAR complex in subcellular morphogenesis of tracheal terminal cells in Drosophila melanogaster.

Jones TA, Metzstein MM.

Genetics. 2011 Sep;189(1):153-64. doi: 10.1534/genetics.111.130351. Epub 2011 Jul 12.


Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia.

Rolls MM, Albertson R, Shih HP, Lee CY, Doe CQ.

J Cell Biol. 2003 Dec 8;163(5):1089-98. Epub 2003 Dec 1.


IKKepsilon: a kinase at the intersection of signaling and membrane traffic.

Gould GW.

Sci Signal. 2011 Jun 14;4(177):pe30. doi: 10.1126/scisignal.2002186. Review.


aPKC is a key polarity determinant in coordinating the function of three distinct cell polarities during collective migration.

Wang H, Qiu Z, Xu Z, Chen SJ, Luo J, Wang X, Chen J.

Development. 2018 May 2;145(9). pii: dev158444. doi: 10.1242/dev.158444.


Lgl and its phosphorylation by aPKC regulate oocyte polarity formation in Drosophila.

Tian AG, Deng WM.

Development. 2008 Feb;135(3):463-71. Epub 2007 Dec 19.


A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

Plant PJ, Fawcett JP, Lin DC, Holdorf AD, Binns K, Kulkarni S, Pawson T.

Nat Cell Biol. 2003 Apr;5(4):301-8.


Interplay between the transcription factor Zif and aPKC regulates neuroblast polarity and self-renewal.

Chang KC, Garcia-Alvarez G, Somers G, Sousa-Nunes R, Rossi F, Lee YY, Soon SB, Gonzalez C, Chia W, Wang H.

Dev Cell. 2010 Nov 16;19(5):778-85. doi: 10.1016/j.devcel.2010.10.007.

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