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Items: 1 to 20 of 143

1.

Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling.

Halls ML, Yeatman HR, Nowell CJ, Thompson GL, Gondin AB, Civciristov S, Bunnett NW, Lambert NA, Poole DP, Canals M.

Sci Signal. 2016 Feb 9;9(414):ra16. doi: 10.1126/scisignal.aac9177.

PMID:
26861044
2.

Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization.

Chu J, Zheng H, Zhang Y, Loh HH, Law PY.

Cell Signal. 2010 Apr;22(4):684-96. doi: 10.1016/j.cellsig.2009.12.003. Epub 2010 Jan 5.

3.

Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells.

Johnson EA, Oldfield S, Braksator E, Gonzalez-Cuello A, Couch D, Hall KJ, Mundell SJ, Bailey CP, Kelly E, Henderson G.

Mol Pharmacol. 2006 Aug;70(2):676-85. Epub 2006 May 8.

PMID:
16682505
4.

Biased μ-opioid receptor agonists diversely regulate lateral mobility and functional coupling of the receptor to its cognate G proteins.

Melkes B, Hejnova L, Novotny J.

Naunyn Schmiedebergs Arch Pharmacol. 2016 Dec;389(12):1289-1300. Epub 2016 Sep 6.

PMID:
27600870
5.

RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons.

Rodríguez-Muñoz M, de la Torre-Madrid E, Gaitán G, Sánchez-Blázquez P, Garzón J.

Cell Signal. 2007 Dec;19(12):2558-71. Epub 2007 Aug 15.

PMID:
17825524
6.

Phosphorylation of the mu-opioid receptor at tyrosine 166 (Tyr3.51) in the DRY motif reduces agonist efficacy.

Clayton CC, Bruchas MR, Lee ML, Chavkin C.

Mol Pharmacol. 2010 Mar;77(3):339-47. doi: 10.1124/mol.109.060558. Epub 2009 Dec 3.

7.

Modulation of μ-opioid receptor signaling by RGS19 in SH-SY5Y cells.

Wang Q, Traynor JR.

Mol Pharmacol. 2013 Feb;83(2):512-20. doi: 10.1124/mol.112.081992. Epub 2012 Nov 29.

9.

Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins.

Rodríguez-Muñoz M, de la Torre-Madrid E, Sánchez-Blázquez P, Garzón J.

Mol Pain. 2007 Jul 17;3:19.

10.

Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine.

Bailey CP, Couch D, Johnson E, Griffiths K, Kelly E, Henderson G.

J Neurosci. 2003 Nov 19;23(33):10515-20.

11.

Opioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment.

Duraffourd C, Kumala E, Anselmi L, Brecha NC, Sternini C.

PLoS One. 2014 Oct 10;9(10):e110230. doi: 10.1371/journal.pone.0110230. eCollection 2014.

12.

Functional characterization of human variants of the mu-opioid receptor gene.

Ravindranathan A, Joslyn G, Robertson M, Schuckit MA, Whistler JL, White RL.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10811-6. doi: 10.1073/pnas.0904509106. Epub 2009 Jun 15.

13.

Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375.

Schulz S, Mayer D, Pfeiffer M, Stumm R, Koch T, Höllt V.

EMBO J. 2004 Aug 18;23(16):3282-9. Epub 2004 Jul 22.

14.

Mu opioid receptor activation enhances regulator of G protein signaling 4 association with the mu opioid receptor/G protein complex in a GTP-dependent manner.

Santhappan R, Crowder AT, Gouty S, Cox BM, Côté TE.

J Neurochem. 2015 Oct;135(1):76-87. doi: 10.1111/jnc.13222. Epub 2015 Jul 16.

15.

Enhancement of morphine analgesic effect with induction of mu-opioid receptor endocytosis in rats.

Hashimoto T, Saito Y, Yamada K, Hara N, Kirihara Y, Tsuchiya M.

Anesthesiology. 2006 Sep;105(3):574-80.

PMID:
16931992
16.

ABIN-1 Negatively Regulates μ-Opioid Receptor Function.

Zhou P, Jiang J, Yan H, Li Y, Zhao J, Wang X, Su R, Gong Z.

Mol Pharmacol. 2018 Feb;93(2):36-48. doi: 10.1124/mol.117.109009. Epub 2017 Dec 13.

PMID:
29237725
17.

Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I.

Burford NT, Tolbert LM, Sadee W.

Eur J Pharmacol. 1998 Jan 19;342(1):123-6.

PMID:
9544801
18.

Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons.

Jaremko KM, Thompson NL Jr, Reyes BA, Jin J, Ebersole B, Jenney CB, Grigson PS, Levenson R, Berrettini WH, Van Bockstaele EJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Apr 3;50:53-65. doi: 10.1016/j.pnpbp.2013.12.003. Epub 2013 Dec 12.

19.

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