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Items: 1 to 20 of 94

1.

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.

Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ.

Nat Commun. 2016 Feb 1;7:10494. doi: 10.1038/ncomms10494.

2.

Leptin and adiponectin DNA methylation levels in adipose tissues and blood cells are associated with BMI, waist girth and LDL-cholesterol levels in severely obese men and women.

Houde AA, Légaré C, Biron S, Lescelleur O, Biertho L, Marceau S, Tchernof A, Vohl MC, Hivert MF, Bouchard L.

BMC Med Genet. 2015 May 1;16:29. doi: 10.1186/s12881-015-0174-1.

4.

Regulation of Fto/Ftm gene expression in mice and humans.

Stratigopoulos G, Padilla SL, LeDuc CA, Watson E, Hattersley AT, McCarthy MI, Zeltser LM, Chung WK, Leibel RL.

Am J Physiol Regul Integr Comp Physiol. 2008 Apr;294(4):R1185-96. doi: 10.1152/ajpregu.00839.2007. Epub 2008 Feb 6. Erratum in: Am J Physiol Regul Integr Comp Physiol. 2008 Oct;295(4):R1360-3.

5.

Association between leptin gene expression in subcutaneous adipose tissue and circulating leptin levels in obese patients with psoriasis.

Mitsuyama S, Abe F, Kimura M, Yoshida M, Higuchi T.

Arch Dermatol Res. 2015 Aug;307(6):539-44. doi: 10.1007/s00403-015-1581-z. Epub 2015 Jun 9.

PMID:
26054710
6.

Common genetic variation in the SERPINF1 locus determines overall adiposity, obesity-related insulin resistance, and circulating leptin levels.

Böhm A, Ordelheide AM, Machann J, Heni M, Ketterer C, Machicao F, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

PLoS One. 2012;7(3):e34035. doi: 10.1371/journal.pone.0034035. Epub 2012 Mar 23.

7.

Genetic variants of FTO influence adiposity, insulin sensitivity, leptin levels, and resting metabolic rate in the Quebec Family Study.

Do R, Bailey SD, Desbiens K, Belisle A, Montpetit A, Bouchard C, Pérusse L, Vohl MC, Engert JC.

Diabetes. 2008 Apr;57(4):1147-50. doi: 10.2337/db07-1267. Epub 2008 Mar 3.

8.

Examining the Causal Role of Leptin in Alzheimer Disease: A Mendelian Randomization Study.

Romo ML, Schooling CM.

Neuroendocrinology. 2017;105(2):182-188. doi: 10.1159/000475713. Epub 2017 Apr 19.

9.

Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin.

Odle AK, Haney A, Allensworth-James M, Akhter N, Childs GV.

Endocrinology. 2014 Nov;155(11):4316-28. doi: 10.1210/en.2014-1172. Epub 2014 Aug 13.

10.

Serum concentrations and expressions of serum amyloid A and leptin in adipose tissue are interrelated: the Genobin Study.

Lappalainen T, Kolehmainen M, Schwab U, Pulkkinen L, Laaksonen DE, Rauramaa R, Uusitupa M, Gylling H.

Eur J Endocrinol. 2008 Mar;158(3):333-41. doi: 10.1530/EJE-07-0598.

PMID:
18299466
11.

Aliskiren reduces body-weight gain, adiposity and plasma leptin during diet-induced obesity.

Stucchi P, Cano V, Ruiz-Gayo M, Fernández-Alfonso MS.

Br J Pharmacol. 2009 Oct;158(3):771-8. doi: 10.1111/j.1476-5381.2009.00355.x. Epub 2009 Aug 19.

12.

Regulation of adiponectin and leptin gene expression in white and brown adipose tissues: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting.

Zhang Y, Matheny M, Zolotukhin S, Tumer N, Scarpace PJ.

Biochim Biophys Acta. 2002 Oct 10;1584(2-3):115-22.

PMID:
12385894
13.

Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.

Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Huebner AK, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T.

J Neuroendocrinol. 2013 Jan;25(1):14-22. doi: 10.1111/j.1365-2826.2012.02366.x.

PMID:
22849972
14.
15.

Serum and gene expression levels of leptin and adiponectin in rats susceptible or resistant to diet-induced obesity.

Pérez-Echarri N, Pérez-Matute P, Martínez JA, Marti A, Moreno-Aliaga MJ.

J Physiol Biochem. 2005 Jun;61(2):333-42.

PMID:
16180331
16.

Construction and Analysis of an Adipose Tissue-Specific and Methylation-Sensitive Promoter of Leptin Gene.

Zhang Q, Xu D, Zhang M, Dong X, Dong H, Pan Q.

Appl Biochem Biotechnol. 2016 Nov;180(6):1213-1226. Epub 2016 Jun 14.

PMID:
27299919
17.

Genetics of leptin expression in baboons.

Cole SA, Martin LJ, Peebles KW, Leland MM, Rice K, VandeBerg JL, Blangero J, Comuzzie AG.

Int J Obes Relat Metab Disord. 2003 Jul;27(7):778-83.

PMID:
12821961
18.

Effects of isolated GH deficiency on adipose tissue, feeding and adipokines in mice.

Recinella L, Shohreh R, Salvatori R, Orlando G, Vacca M, Brunetti L.

Growth Horm IGF Res. 2013 Dec;23(6):237-42. doi: 10.1016/j.ghir.2013.08.004. Epub 2013 Aug 27.

PMID:
24021480
19.

Mechanisms for LEPR-mediated regulation of leptin expression in brown and white adipocytes in rat pups.

Zhang Y, Hufnagel C, Eiden S, Guo KY, Diaz PA, Leibel R, Schmidt I.

Physiol Genomics. 2001 Jan 19;4(3):189-99.

PMID:
11160998
20.

Dietary modulation of circulating leptin levels: site-specific changes in fat deposition and ob mRNA expression.

Walker CG, Bryson JM, Phuyal JL, Caterson ID.

Horm Metab Res. 2002 Apr;34(4):176-81.

PMID:
11987025

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