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Items: 1 to 20 of 118

1.

Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.

Ebbert MTW, Boehme KL, Wadsworth ME, Staley LA; Alzheimer's Disease Neuroimaging Initiative; Alzheimer's Disease Genetics Consortium, Mukherjee S, Crane PK, Ridge PG, Kauwe JSK.

Alzheimers Dement. 2016 Feb;12(2):121-129. doi: 10.1016/j.jalz.2015.08.163. Epub 2015 Oct 9.

2.

Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals.

Nordestgaard LT, Tybjærg-Hansen A, Rasmussen KL, Nordestgaard BG, Frikke-Schmidt R.

BMC Med. 2018 Mar 14;16(1):39. doi: 10.1186/s12916-018-1029-3.

3.

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC; Alzheimer's Disease Neuroimaging Initiative, van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S; CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alpérovitch A, Lathrop M; EADI1 consortium, Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Björnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J.

Nat Genet. 2011 May;43(5):429-35. doi: 10.1038/ng.803. Epub 2011 Apr 3.

4.

Combined effects of Alzheimer risk variants in the CLU and ApoE genes on ventricular expansion patterns in the elderly.

Roussotte FF, Gutman BA, Madsen SK, Colby JB, Thompson PM; Alzheimer's Disease Neuroimaging Initiative.

J Neurosci. 2014 May 7;34(19):6537-45. doi: 10.1523/JNEUROSCI.5236-13.2014.

5.

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

Elias-Sonnenschein LS, Helisalmi S, Natunen T, Hall A, Paajanen T, Herukka SK, Laitinen M, Remes AM, Koivisto AM, Mattila KM, Lehtimäki T, Verhey FR, Visser PJ, Soininen H, Hiltunen M.

PLoS One. 2013;8(4):e59676. doi: 10.1371/journal.pone.0059676. Epub 2013 Apr 3.

6.

Association of CD33 and MS4A cluster variants with Alzheimer's disease in East Asian populations.

Mao YF, Guo ZY, Pu JL, Chen YX, Zhang BR.

Neurosci Lett. 2015 Nov 16;609:235-9. doi: 10.1016/j.neulet.2015.10.007. Epub 2015 Oct 9.

PMID:
26455864
7.

Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study.

Bressler J, Mosley TH, Penman A, Gottesman RF, Windham BG, Knopman DS, Wruck LM, Boerwinkle E.

Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):269-282. doi: 10.1002/ajmg.b.32509. Epub 2016 Oct 26.

8.

Population-based analysis of Alzheimer's disease risk alleles implicates genetic interactions.

Ebbert MT, Ridge PG, Wilson AR, Sharp AR, Bailey M, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Kauwe JS.

Biol Psychiatry. 2014 May 1;75(9):732-7. doi: 10.1016/j.biopsych.2013.07.008. Epub 2013 Aug 13.

9.

Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.

Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, Mayeux R; NIA-LOAD/NCRAD Family Study Group.

PLoS Genet. 2011 Feb;7(2):e1001308. doi: 10.1371/journal.pgen.1001308. Epub 2011 Feb 17.

10.

[Analysis of clusterin gene (CLU/APOJ) polymorphism in Alzheimer's disease patients and in normal cohorts from Russian populations].

Golenkina SA, Gol'tsov AIu, Kuznetsova IL, Grigorenko AP, Andreeva TV, Reshetov DA, Kunizheva SS, Shagam LI, Morozova IIu, Goldenkova-Pavlova IV, Shimshilashvili Kh, Viacheslavova AO, Faskhutdinova G, Gareeva AÉ, Zaĭnullina AG, Khusnutdinova ÉK, Puzyrev VP, Stepanov VA, Kolotvin AV, Samokhodskaia LM, Selezneva ND, Gavrilova SI, Rogaev EI.

Mol Biol (Mosk). 2010 Jul-Aug;44(4):620-6. Russian.

PMID:
20873220
11.

Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects.

Pedraza O, Allen M, Jennette K, Carrasquillo M, Crook J, Serie D, Pankratz VS, Palusak R, Nguyen T, Malphrus K, Ma L, Bisceglio G, Roberts RO, Lucas JA, Ivnik RJ, Smith GE, Graff-Radford NR, Petersen RC, Younkin SG, Ertekin-Taner N.

Alzheimers Dement. 2014 Mar;10(2):205-13. doi: 10.1016/j.jalz.2013.01.016. Epub 2013 May 2.

12.

Association between CLU gene rs11136000 polymorphism and Alzheimer's disease: an updated meta-analysis.

Zhu R, Liu X, He Z.

Neurol Sci. 2018 Apr;39(4):679-689. doi: 10.1007/s10072-018-3259-8. Epub 2018 Feb 2.

PMID:
29396813
13.

Association of GWAS Top Genes With Late-Onset Alzheimer's Disease in Colombian Population.

Moreno DJ, Ruiz S, Ríos Á, Lopera F, Ostos H, Via M, Bedoya G.

Am J Alzheimers Dis Other Demen. 2017 Feb;32(1):27-35. doi: 10.1177/1533317516679303. Epub 2017 Jan 13.

PMID:
28084078
14.

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.

Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J.

Nat Genet. 2009 Oct;41(10):1088-93. doi: 10.1038/ng.440. Epub 2009 Sep 6. Erratum in: Nat Genet. 2009 Oct;41(10):1156. Nat Genet. 2013 Jun;45(6):712. Haun, Reinhard [added].

15.

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.

Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fiévet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O; European Alzheimer's Disease Initiative Investigators, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanché H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alpérovitch A, Lathrop M, Amouyel P.

Nat Genet. 2009 Oct;41(10):1094-9. doi: 10.1038/ng.439. Epub 2009 Sep 6.

PMID:
19734903
16.

Effect of CLU and PICALM polymorphisms on AD risk: A study from south India.

Shankarappa BM, Kota LN, Purushottam M, Nagpal K, Mukherjee O, Viswanath B, Varghese M, Bharath S, Jain S.

Asian J Psychiatr. 2017 Jun;27:7-11. doi: 10.1016/j.ajp.2016.12.017. Epub 2016 Dec 29.

PMID:
28558900
17.

rs3851179 Polymorphism at 5' to the PICALM Gene is Associated with Alzheimer and Parkinson Diseases in Brazilian Population.

Santos-Rebouças CB, Gonçalves AP, Dos Santos JM, Abdala BB, Motta LB, Laks J, de Borges MB, de Rosso ALZ, Pereira JS, Nicaretta DH, Pimentel MMG.

Neuromolecular Med. 2017 Sep;19(2-3):293-299. doi: 10.1007/s12017-017-8444-z. Epub 2017 May 31.

PMID:
28567584
18.

Clusterin variants are not associated with southern Chinese patients with Alzheimer's disease.

Lu SJ, Li HL, Sun YM, Liu ZJ, Yang P, Wu ZY.

Neurobiol Aging. 2014 Nov;35(11):2656.e9-2656.e11. doi: 10.1016/j.neurobiolaging.2014.05.015. Epub 2014 May 29.

PMID:
24958191
19.

A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.

Deming Y, Xia J, Cai Y, Lord J, Holmans P, Bertelsen S, Holtzman D, Morris JC, Bales K, Pickering EH, Kauwe J, Goate A, Cruchaga C; Alzheimer's Disease Neuroimaging Initiative (ADNI).

Neurobiol Aging. 2016 Jan;37:208.e1-208.e9. doi: 10.1016/j.neurobiolaging.2015.09.009. Epub 2015 Sep 25.

20.

Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer's disease in a southern Chinese population.

Chen LH, Kao PY, Fan YH, Ho DT, Chan CS, Yik PY, Ha JC, Chu LW, Song YQ.

Neurobiol Aging. 2012 Jan;33(1):210.e1-7. doi: 10.1016/j.neurobiolaging.2011.09.016. Epub 2011 Oct 19.

PMID:
22015308

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