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Items: 1 to 20 of 112

1.

Transcriptomic-Wide Discovery of Direct and Indirect HuR RNA Targets in Activated CD4+ T Cells.

Techasintana P, Davis JW, Gubin MM, Magee JD, Atasoy U.

PLoS One. 2015 Jul 10;10(7):e0129321. doi: 10.1371/journal.pone.0129321. eCollection 2015.

2.

Conditional knockout of the RNA-binding protein HuR in CD4⁺ T cells reveals a gene dosage effect on cytokine production.

Gubin MM, Techasintana P, Magee JD, Dahm GM, Calaluce R, Martindale JL, Whitney MS, Franklin CL, Besch-Williford C, Hollingsworth JW, Abdelmohsen K, Gorospe M, Atasoy U.

Mol Med. 2014 Mar 20;20:93-108. doi: 10.2119/molmed.2013.00127.

3.

Quantifying RNA binding sites transcriptome-wide using DO-RIP-seq.

Nicholson CO, Friedersdorf M, Keene JD.

RNA. 2017 Jan;23(1):32-46. Epub 2016 Oct 14.

4.

The RNA binding protein HuR differentially regulates unique subsets of mRNAs in estrogen receptor negative and estrogen receptor positive breast cancer.

Calaluce R, Gubin MM, Davis JW, Magee JD, Chen J, Kuwano Y, Gorospe M, Atasoy U.

BMC Cancer. 2010 Apr 6;10:126. doi: 10.1186/1471-2407-10-126.

5.

Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR.

Stellato C, Gubin MM, Magee JD, Fang X, Fan J, Tartar DM, Chen J, Dahm GM, Calaluce R, Mori F, Jackson GA, Casolaro V, Franklin CL, Atasoy U.

J Immunol. 2011 Jul 1;187(1):441-9. doi: 10.4049/jimmunol.1001881. Epub 2011 May 25.

6.

DO-RIP-seq to quantify RNA binding sites transcriptome-wide.

Nicholson CO, Friedersdorf MB, Bisogno LS, Keene JD.

Methods. 2017 Apr 15;118-119:16-23. doi: 10.1016/j.ymeth.2016.11.004. Epub 2016 Nov 10.

7.

Identification of tumorigenesis-related mRNAs associated with RNA-binding protein HuR in thyroid cancer cells.

Baldan F, Mio C, Allegri L, Conzatti K, Toffoletto B, Puppin C, Radovic S, Vascotto C, Russo D, Di Loreto C, Damante G.

Oncotarget. 2016 Sep 27;7(39):63388-63407. doi: 10.18632/oncotarget.11255.

8.

B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.

DeMicco A, Naradikian MS, Sindhava VJ, Yoon JH, Gorospe M, Wertheim GB, Cancro MP, Bassing CH.

J Immunol. 2015 Oct 1;195(7):3449-62. doi: 10.4049/jimmunol.1500512. Epub 2015 Aug 28.

9.

The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells.

Chen J, Martindale JL, Cramer C, Gorospe M, Atasoy U, Drew PD, Yu S.

J Biol Chem. 2017 Sep 1;292(35):14532-14543. doi: 10.1074/jbc.M117.782771. Epub 2017 Jul 6.

10.

Delivery of Therapeutics Targeting the mRNA-Binding Protein HuR Using 3DNA Nanocarriers Suppresses Ovarian Tumor Growth.

Huang YH, Peng W, Furuuchi N, Gerhart J, Rhodes K, Mukherjee N, Jimbo M, Gonye GE, Brody JR, Getts RC, Sawicki JA.

Cancer Res. 2016 Mar 15;76(6):1549-59. doi: 10.1158/0008-5472.CAN-15-2073. Epub 2016 Feb 26. Erratum in: Cancer Res. 2016 Jun 1;76(11):3437.

11.

Posttranscriptional regulation of IL-13 in T cells: role of the RNA-binding protein HuR.

Casolaro V, Fang X, Tancowny B, Fan J, Wu F, Srikantan S, Asaki SY, De Fanis U, Huang SK, Gorospe M, Atasoy UX, Stellato C.

J Allergy Clin Immunol. 2008 Apr;121(4):853-9.e4. doi: 10.1016/j.jaci.2007.12.1166. Epub 2008 Feb 14.

12.

Early exposure to IL-4 stabilizes IL-4 mRNA in CD4+ T cells via RNA-binding protein HuR.

Yarovinsky TO, Butler NS, Monick MM, Hunninghake GW.

J Immunol. 2006 Oct 1;177(7):4426-35.

13.

Posttranscriptional gene regulation of IL-17 by the RNA-binding protein HuR is required for initiation of experimental autoimmune encephalomyelitis.

Chen J, Cascio J, Magee JD, Techasintana P, Gubin MM, Dahm GM, Calaluce R, Yu S, Atasoy U.

J Immunol. 2013 Dec 1;191(11):5441-50. doi: 10.4049/jimmunol.1301188. Epub 2013 Oct 28.

14.

Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation.

Pramanik J, Chen X, Kar G, Henriksson J, Gomes T, Park JE, Natarajan K, Meyer KB, Miao Z, McKenzie ANJ, Mahata B, Teichmann SA.

Genome Med. 2018 Oct 24;10(1):76. doi: 10.1186/s13073-018-0589-3.

15.

The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4+ Th2 Differentiation.

Techasintana P, Ellis JS, Glascock J, Gubin MM, Ridenhour SE, Magee JD, Hart ML, Yao P, Zhou H, Whitney MS, Franklin CL, Martindale JL, Gorospe M, Davis WJ, Fox PL, Li X, Atasoy U.

Immunohorizons. 2017 Aug 1;1(6):109-123. doi: 10.4049/immunohorizons.1700017.

16.

Post-transcriptional regulation of Wnt co-receptor LRP6 and RNA-binding protein HuR by miR-29b in intestinal epithelial cells.

Li Y, Chen G, Wang JY, Zou T, Liu L, Xiao L, Chung HK, Rao JN, Wang JY.

Biochem J. 2016 Jun 1;473(11):1641-9. doi: 10.1042/BCJ20160057. Epub 2016 Apr 18.

17.

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels.

Abdelmohsen K, Srikantan S, Kuwano Y, Gorospe M.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20297-302. doi: 10.1073/pnas.0809376106. Epub 2008 Dec 16.

18.

Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.

Ghosh M, Aguila HL, Michaud J, Ai Y, Wu MT, Hemmes A, Ristimaki A, Guo C, Furneaux H, Hla T.

J Clin Invest. 2009 Dec;119(12):3530-43. doi: 10.1172/JCI38263. Epub 2009 Nov 2.

19.

Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages.

Hoppstädter J, Hachenthal N, Valbuena-Perez JV, Lampe S, Astanina K, Kunze MM, Bruscoli S, Riccardi C, Schmid T, Diesel B, Kiemer AK.

J Biol Chem. 2016 Oct 28;291(44):22949-22960. Epub 2016 Sep 14.

20.

Human antigen R contributes to hepatic stellate cell activation and liver fibrosis.

Woodhoo A, Iruarrizaga-Lejarreta M, Beraza N, García-Rodríguez JL, Embade N, Fernández-Ramos D, Martínez-López N, Gutiérrez-De Juan V, Arteta B, Caballeria J, Lu SC, Mato JM, Varela-Rey M, Martínez-Chantar ML.

Hepatology. 2012 Nov;56(5):1870-82. doi: 10.1002/hep.25828. Epub 2012 Oct 9.

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