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Items: 1 to 20 of 282

1.

A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection.

Ramos-Junior ES, Morandini AC, Almeida-da-Silva CL, Franco EJ, Potempa J, Nguyen KA, Oliveira AC, Zamboni DS, Ojcius DM, Scharfstein J, Coutinho-Silva R.

J Dent Res. 2015 Sep;94(9):1233-42. doi: 10.1177/0022034515593465. Epub 2015 Jul 7.

2.

Activation of NLRP3 and AIM2 inflammasomes by Porphyromonas gingivalis infection.

Park E, Na HS, Song YR, Shin SY, Kim YM, Chung J.

Infect Immun. 2014 Jan;82(1):112-23. doi: 10.1128/IAI.00862-13. Epub 2013 Oct 14.

3.

Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion.

Morandini AC, Ramos-Junior ES, Potempa J, Nguyen KA, Oliveira AC, Bellio M, Ojcius DM, Scharfstein J, Coutinho-Silva R.

J Innate Immun. 2014;6(6):831-45. doi: 10.1159/000363338. Epub 2014 Jun 6.

4.

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

He Y, Franchi L, Núñez G.

J Immunol. 2013 Jan 1;190(1):334-9. doi: 10.4049/jimmunol.1202737. Epub 2012 Dec 7.

5.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

6.

The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.

PMID:
23843215
7.

Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages.

Budai MM, Varga A, Milesz S, Tőzsér J, Benkő S.

Mol Immunol. 2013 Dec;56(4):471-9. doi: 10.1016/j.molimm.2013.05.005. Epub 2013 Aug 1.

PMID:
23911403
8.

The anti-tumorigenic mushroom Agaricus blazei Murill enhances IL-1β production and activates the NLRP3 inflammasome in human macrophages.

Huang TT, Ojcius DM, Young JD, Wu YH, Ko YF, Wong TY, Wu CY, Lu CC, Lai HC.

PLoS One. 2012;7(7):e41383. doi: 10.1371/journal.pone.0041383. Epub 2012 Jul 23.

9.

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G.

J Immunol. 2009 Nov 1;183(9):5823-9. doi: 10.4049/jimmunol.0900444. Epub 2009 Oct 7.

10.

Mechanisms of NLRP3 inflammasome activation and its role in NSAID-induced enteropathy.

Higashimori A, Watanabe T, Nadatani Y, Takeda S, Otani K, Tanigawa T, Yamagami H, Shiba M, Tominaga K, Fujiwara Y, Arakawa T.

Mucosal Immunol. 2016 May;9(3):659-68. doi: 10.1038/mi.2015.89. Epub 2015 Sep 9.

PMID:
26349656
11.

P2X7 receptor-mediated leukocyte recruitment and Porphyromonas gingivalis clearance requires IL-1β production and autocrine IL-1 receptor activation.

Almeida-da-Silva CLC, Ramos-Junior ES, Morandini AC, Rocha GDC, Marinho Y, Tamura AS, de Andrade KQ, Bellio M, Savio LEB, Scharfstein J, Ojcius DM, Coutinho-Silva R.

Immunobiology. 2019 Jan;224(1):50-59. doi: 10.1016/j.imbio.2018.10.008. Epub 2018 Nov 2.

PMID:
30429052
12.

IL-1β production is dependent on the activation of purinergic receptors and NLRP3 pathway in human macrophages.

Gicquel T, Robert S, Loyer P, Victoni T, Bodin A, Ribault C, Gleonnec F, Couillin I, Boichot E, Lagente V.

FASEB J. 2015 Oct;29(10):4162-73. doi: 10.1096/fj.14-267393. Epub 2015 Jun 26.

PMID:
26116704
13.

Alarmin HNP-1 promotes pyroptosis and IL-1β release through different roles of NLRP3 inflammasome via P2X7 in LPS-primed macrophages.

Chen Q, Jin Y, Zhang K, Li H, Chen W, Meng G, Fang X.

Innate Immun. 2014 Apr;20(3):290-300. doi: 10.1177/1753425913490575. Epub 2013 Jun 21.

PMID:
23792296
14.

P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway.

Zhao J, Wang H, Dai C, Wang H, Zhang H, Huang Y, Wang S, Gaskin F, Yang N, Fu SM.

Arthritis Rheum. 2013 Dec;65(12):3176-85. doi: 10.1002/art.38174.

15.

Regulation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated periodontal disease.

Yamaguchi Y, Kurita-Ochiai T, Kobayashi R, Suzuki T, Ando T.

Inflamm Res. 2017 Jan;66(1):59-65. doi: 10.1007/s00011-016-0992-4. Epub 2016 Sep 24.

PMID:
27665233
17.

P2X7 receptor inhibition attenuated sympathetic nerve sprouting after myocardial infarction via the NLRP3/IL-1β pathway.

Yin J, Wang Y, Hu H, Li X, Xue M, Cheng W, Wang Y, Li X, Yang N, Shi Y, Yan S.

J Cell Mol Med. 2017 Nov;21(11):2695-2710. doi: 10.1111/jcmm.13185. Epub 2017 May 4.

18.

The complex P2X7 receptor/inflammasome in perivascular fat tissue of heavy smokers.

Rossi C, Santini E, Chiarugi M, Salvati A, Comassi M, Vitolo E, Madec S, Solini A.

Eur J Clin Invest. 2014;44(3):295-302. doi: 10.1111/eci.12232. Epub 2014 Jan 20.

PMID:
24372548
19.

NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes.

Gustin A, Kirchmeyer M, Koncina E, Felten P, Losciuto S, Heurtaux T, Tardivel A, Heuschling P, Dostert C.

PLoS One. 2015 Jun 19;10(6):e0130624. doi: 10.1371/journal.pone.0130624. eCollection 2015.

20.

Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome.

Darisipudi MN, Allam R, Rupanagudi KV, Anders HJ.

PLoS One. 2011;6(5):e19588. doi: 10.1371/journal.pone.0019588. Epub 2011 May 23.

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