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Items: 1 to 20 of 122

1.

Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection.

Janda E, Lascala A, Carresi C, Parafati M, Aprigliano S, Russo V, Savoia C, Ziviani E, Musolino V, Morani F, Isidoro C, Mollace V.

Autophagy. 2015;11(7):1063-80. doi: 10.1080/15548627.2015.1058683. Erratum in: Autophagy. 2017 Mar 4;13(3):638.

2.

The antidote effect of quinone oxidoreductase 2 inhibitor against paraquat-induced toxicity in vitro and in vivo.

Janda E, Parafati M, Aprigliano S, Carresi C, Visalli V, Sacco I, Ventrice D, Mega T, Vadalá N, Rinaldi S, Musolino V, Palma E, Gratteri S, Rotiroti D, Mollace V.

Br J Pharmacol. 2013 Jan;168(1):46-59. doi: 10.1111/j.1476-5381.2012.01870.x.

3.

Autophagy is a protective response to ethanol neurotoxicity.

Chen G, Ke Z, Xu M, Liao M, Wang X, Qi Y, Zhang T, Frank JA, Bower KA, Shi X, Luo J.

Autophagy. 2012 Nov;8(11):1577-89. doi: 10.4161/auto.21376. Epub 2012 Aug 9.

4.

[The role of the AMPK-mTOR pathway in paraquat-induce autophagy in PC12 cells].

Xu YL, Wu KX, Wang Q, Yu PG, Su XM, Huang M.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2018 Nov 20;36(11):801-807. doi: 10.3760/cma.j.issn.1001-9391.2018.11.001. Chinese.

PMID:
30646639
5.

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia.

Qin AP, Liu CF, Qin YY, Hong LZ, Xu M, Yang L, Liu J, Qin ZH, Zhang HL.

Autophagy. 2010 Aug;6(6):738-53. Epub 2010 Aug 3.

PMID:
20574158
6.

The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells.

Johansson I, Monsen VT, Pettersen K, Mildenberger J, Misund K, Kaarniranta K, Schønberg S, Bjørkøy G.

Autophagy. 2015;11(9):1636-51. doi: 10.1080/15548627.2015.1061170.

7.

Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity.

Garcia-Garcia A, Anandhan A, Burns M, Chen H, Zhou Y, Franco R.

Toxicol Sci. 2013 Nov;136(1):166-82. doi: 10.1093/toxsci/kft188. Epub 2013 Aug 31.

8.

Early LC3 lipidation induced by d-limonene does not rely on mTOR inhibition, ERK activation and ROS production and it is associated with reduced clonogenic capacity of SH-SY5Y neuroblastoma cells.

Berliocchi L, Chiappini C, Adornetto A, Gentile D, Cerri S, Russo R, Bagetta G, Corasaniti MT.

Phytomedicine. 2018 Feb 1;40:98-105. doi: 10.1016/j.phymed.2018.01.005.

PMID:
29496180
9.

tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation.

Li S, Li J, Shen C, Zhang X, Sun S, Cho M, Sun C, Song Z.

Biochim Biophys Acta. 2014 Jan;1841(1):22-33. doi: 10.1016/j.bbalip.2013.09.004. Epub 2013 Sep 19.

10.

Mitophagy regulates mitochondrial network signaling, oxidative stress, and apoptosis during myoblast differentiation.

Baechler BL, Bloemberg D, Quadrilatero J.

Autophagy. 2019 Apr 7:1-14. doi: 10.1080/15548627.2019.1591672. [Epub ahead of print]

PMID:
30859901
11.

Andrographolide Protects PC12 Cells Against β-Amyloid-Induced Autophagy-Associated Cell Death Through Activation of the Nrf2-Mediated p62 Signaling Pathway.

Gu L, Yu Q, Li Q, Zhang L, Lu H, Zhang X.

Int J Mol Sci. 2018 Sep 19;19(9). pii: E2844. doi: 10.3390/ijms19092844.

12.

Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells.

Yoon YH, Cho KS, Hwang JJ, Lee SJ, Choi JA, Koh JY.

Invest Ophthalmol Vis Sci. 2010 Nov;51(11):6030-7. doi: 10.1167/iovs.10-5278. Epub 2010 Jun 23.

PMID:
20574031
13.

Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways.

Navarro-Yepes J, Anandhan A, Bradley E, Bohovych I, Yarabe B, de Jong A, Ovaa H, Zhou Y, Khalimonchuk O, Quintanilla-Vega B, Franco R.

Mol Neurobiol. 2016 Oct;53(8):5229-51. doi: 10.1007/s12035-015-9414-9. Epub 2015 Sep 26.

14.

Activation of apoptosis signal-regulating kinase 1 is a key factor in paraquat-induced cell death: modulation by the Nrf2/Trx axis.

Niso-Santano M, González-Polo RA, Bravo-San Pedro JM, Gómez-Sánchez R, Lastres-Becker I, Ortiz-Ortiz MA, Soler G, Morán JM, Cuadrado A, Fuentes JM; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED).

Free Radic Biol Med. 2010 May 15;48(10):1370-81. doi: 10.1016/j.freeradbiomed.2010.02.024. Epub 2010 Mar 2.

PMID:
20202476
15.

ASK1 overexpression accelerates paraquat-induced autophagy via endoplasmic reticulum stress.

Niso-Santano M, Bravo-San Pedro JM, Gómez-Sánchez R, Climent V, Soler G, Fuentes JM, González-Polo RA.

Toxicol Sci. 2011 Jan;119(1):156-68. doi: 10.1093/toxsci/kfq313. Epub 2010 Oct 7.

PMID:
20929985
16.

Paraquat and MPTP induce alteration in the expression profile of long noncoding RNAs in the substantia nigra of mice: Role of the transcription factor Nrf2.

Wang L, Yang H, Wang Q, Zhang Q, Wang Z, Zhang Q, Wu S, Li H.

Toxicol Lett. 2018 Jul;291:11-28. doi: 10.1016/j.toxlet.2018.04.002. Epub 2018 Apr 5.

PMID:
29627306
17.

Binding preference of p62 towards LC3-ll during dopaminergic neurotoxin-induced impairment of autophagic flux.

Lim J, Kim HW, Youdim MB, Rhyu IJ, Choe KM, Oh YJ.

Autophagy. 2011 Jan;7(1):51-60. Epub 2011 Jan 1.

PMID:
21045561
18.

Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity.

Park JS, Lee DH, Lee YS, Oh E, Bae KH, Oh KJ, Kim H, Bae SH.

Autophagy. 2019 Mar 25:1-20. doi: 10.1080/15548627.2019.1598751. [Epub ahead of print]

PMID:
30907226
19.

Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin.

Fabrizi C, Pompili E, De Vito S, Somma F, Catizone A, Ricci G, Lenzi P, Fornai F, Fumagalli L.

Neurotoxicology. 2016 Jan;52:12-22. doi: 10.1016/j.neuro.2015.10.004. Epub 2015 Oct 13.

PMID:
26459185
20.

c-Jun N-terminal kinase activation by nitrobenzoxadiazoles leads to late-stage autophagy inhibition.

Palumbo C, De Luca A, Rosato N, Forgione M, Rotili D, Caccuri AM.

J Transl Med. 2016 Feb 4;14:37. doi: 10.1186/s12967-016-0796-x.

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