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Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson's disease.

Acquarone M, de Melo TM, Meireles F, Brito-Moreira J, Oliveira G, Ferreira ST, Castro NG, Tovar-Moll F, Houzel JC, Rehen SK.

Front Cell Neurosci. 2015 Apr 8;9:97. doi: 10.3389/fncel.2015.00097. eCollection 2015.


Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery in Parkinsonian mice.

Cui YF, Hargus G, Xu JC, Schmid JS, Shen YQ, Glatzel M, Schachner M, Bernreuther C.

Brain. 2010 Jan;133(Pt 1):189-204. doi: 10.1093/brain/awp290. Epub 2009 Dec 7.


Docosahexaenoic acid promotes dopaminergic differentiation in induced pluripotent stem cells and inhibits teratoma formation in rats with Parkinson-like pathology.

Chang YL, Chen SJ, Kao CL, Hung SC, Ding DC, Yu CC, Chen YJ, Ku HH, Lin CP, Lee KH, Chen YC, Wang JJ, Hsu CC, Chen LK, Li HY, Chiou SH.

Cell Transplant. 2012;21(1):313-32. doi: 10.3727/096368911X580572. Epub 2011 Jun 7.


Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons.

Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, Moore M, Osborn T, Cooper O, Spealman R, Hallett P, Isacson O.

Stem Cells. 2013 Aug;31(8):1548-62. doi: 10.1002/stem.1415.


Generation and transplantation of dopaminergic neurons derived from embryonic stem cells.

Khanna A, Swistowska AM, Rao MS, Zeng X.

Curr Stem Cell Res Ther. 2007 May;2(2):139-47. Review.


Stem cell grafting improves both motor and cognitive impairments in a genetic model of Parkinson's disease, the aphakia (ak) mouse.

Moon J, Lee HS, Kang JM, Park J, Leung A, Hong S, Chung S, Kim KS.

Cell Transplant. 2013;22(7):1263-79. doi: 10.3727/096368912X657242. Epub 2012 Oct 2.


Clinical translation of stem cell transplantation in Parkinson's disease.

Lindvall O.

J Intern Med. 2016 Jan;279(1):30-40. doi: 10.1111/joim.12415. Epub 2015 Aug 31. Review.


Stem cell-based therapy for Parkinson's disease.

Correia AS, Anisimov SV, Li JY, Brundin P.

Ann Med. 2005;37(7):487-98. Review.


Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell.

Kwon YW, Chung YJ, Kim J, Lee HJ, Park J, Roh TY, Cho HJ, Yoon CH, Koo BK, Kim HS.

PLoS One. 2014 Jan 22;9(1):e85736. doi: 10.1371/journal.pone.0085736. eCollection 2014.


Intrastriatal transplantation of adult human neural crest-derived stem cells improves functional outcome in parkinsonian rats.

Müller J, Ossig C, Greiner JF, Hauser S, Fauser M, Widera D, Kaltschmidt C, Storch A, Kaltschmidt B.

Stem Cells Transl Med. 2015 Jan;4(1):31-43. doi: 10.5966/sctm.2014-0078. Epub 2014 Dec 5.


Subthalamic GAD gene transfer in Parkinson disease patients who are candidates for deep brain stimulation.

During MJ, Kaplitt MG, Stern MB, Eidelberg D.

Hum Gene Ther. 2001 Aug 10;12(12):1589-91.


Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells.

Cajánek L, Ribeiro D, Liste I, Parish CL, Bryja V, Arenas E.

Stem Cells. 2009 Dec;27(12):2917-27. doi: 10.1002/stem.210.


Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease.

Hedlund E, Pruszak J, Lardaro T, Ludwig W, Viñuela A, Kim KS, Isacson O.

Stem Cells. 2008 Jun;26(6):1526-36. doi: 10.1634/stemcells.2007-0996. Epub 2008 Apr 3.


Reducing glypican-4 in ES cells improves recovery in a rat model of Parkinson's disease by increasing the production of dopaminergic neurons and decreasing teratoma formation.

Fico A, de Chevigny A, Melon C, Bohic M, Kerkerian-Le Goff L, Maina F, Dono R, Cremer H.

J Neurosci. 2014 Jun 11;34(24):8318-23. doi: 10.1523/JNEUROSCI.2501-13.2014.


Potential application of induced pluripotent stem cells in cell replacement therapy for Parkinson's disease.

Chen LW, Kuang F, Wei LC, Ding YX, Yung KK, Chan YS.

CNS Neurol Disord Drug Targets. 2011 Jun;10(4):449-58. Review.


Growth factors and feeder cells promote differentiation of human embryonic stem cells into dopaminergic neurons: a novel role for fibroblast growth factor-20.

Correia AS, Anisimov SV, Li JY, Brundin P.

Front Neurosci. 2008 Jul 7;2(1):26-34. doi: 10.3389/neuro.01.011.2008. eCollection 2008 Jul.


[Neuromodulation for Parkinson's disease].

Takahashi J.

Rinsho Shinkeigaku. 2008 Apr;48(4):233-41. Review. Japanese.


Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.

Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, Yang L, Beal MF, Surmeier DJ, Kordower JH, Tabar V, Studer L.

Nature. 2011 Nov 6;480(7378):547-51. doi: 10.1038/nature10648.


Intrastriatal transplantation of mouse bone marrow-derived stem cells improves motor behavior in a mouse model of Parkinson's disease.

Offen D, Barhum Y, Levy YS, Burshtein A, Panet H, Cherlow T, Melamed E.

J Neural Transm Suppl. 2007;(72):133-43.


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