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Items: 1 to 20 of 146

1.

Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance.

Schreiweis C, Bornschein U, Burguière E, Kerimoglu C, Schreiter S, Dannemann M, Goyal S, Rea E, French CA, Puliyadi R, Groszer M, Fisher SE, Mundry R, Winter C, Hevers W, Pääbo S, Enard W, Graybiel AM.

Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):14253-8. doi: 10.1073/pnas.1414542111. Epub 2014 Sep 15.

2.

A humanized version of Foxp2 does not affect ultrasonic vocalization in adult mice.

Hammerschmidt K, Schreiweis C, Minge C, Pääbo S, Fischer J, Enard W.

Genes Brain Behav. 2015 Nov;14(8):583-90. doi: 10.1111/gbb.12237. Epub 2015 Aug 25.

3.

A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.

Enard W, Gehre S, Hammerschmidt K, Hölter SM, Blass T, Somel M, Brückner MK, Schreiweis C, Winter C, Sohr R, Becker L, Wiebe V, Nickel B, Giger T, Müller U, Groszer M, Adler T, Aguilar A, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Favor J, Fuchs H, Gailus-Durner V, Hans W, Hölzlwimmer G, Javaheri A, Kalaydjiev S, Kallnik M, Kling E, Kunder S, Mossbrugger I, Naton B, Racz I, Rathkolb B, Rozman J, Schrewe A, Busch DH, Graw J, Ivandic B, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Zimmer A, Fisher SE, Morgenstern R, Arendt T, de Angelis MH, Fischer J, Schwarz J, Pääbo S.

Cell. 2009 May 29;137(5):961-71. doi: 10.1016/j.cell.2009.03.041.

4.

An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning.

French CA, Jin X, Campbell TG, Gerfen E, Groszer M, Fisher SE, Costa RM.

Mol Psychiatry. 2012 Nov;17(11):1077-85. doi: 10.1038/mp.2011.105. Epub 2011 Aug 30.

5.

Expression of Foxp2, a gene involved in speech and language, in the developing and adult striatum.

Takahashi K, Liu FC, Hirokawa K, Takahashi H.

J Neurosci Res. 2003 Jul 1;73(1):61-72.

PMID:
12815709
6.

FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution.

Enard W.

Curr Opin Neurobiol. 2011 Jun;21(3):415-24. doi: 10.1016/j.conb.2011.04.008. Epub 2011 May 16. Review.

PMID:
21592779
7.

Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA release.

van Rhijn JR, Fisher SE, Vernes SC, Nadif Kasri N.

Brain Struct Funct. 2018 Dec;223(9):4211-4226. doi: 10.1007/s00429-018-1746-6. Epub 2018 Sep 5.

8.

Humanized Foxp2 specifically affects cortico-basal ganglia circuits.

Reimers-Kipping S, Hevers W, Pääbo S, Enard W.

Neuroscience. 2011 Feb 23;175:75-84. doi: 10.1016/j.neuroscience.2010.11.042. Epub 2010 Nov 25.

PMID:
21111790
9.

Enhanced procedural learning of speech sound categories in a genetic variant of FOXP2.

Chandrasekaran B, Yi HG, Blanco NJ, McGeary JE, Maddox WT.

J Neurosci. 2015 May 20;35(20):7808-12. doi: 10.1523/JNEUROSCI.4706-14.2015.

10.

Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.

Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, Ragoussis J, Davies KE, Geschwind DH, Fisher SE.

PLoS Genet. 2011 Jul;7(7):e1002145. doi: 10.1371/journal.pgen.1002145. Epub 2011 Jul 7.

11.

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c.

Chen YC, Kuo HY, Bornschein U, Takahashi H, Chen SY, Lu KM, Yang HY, Chen GM, Lin JR, Lee YH, Chou YC, Cheng SJ, Chien CT, Enard W, Hevers W, Pääbo S, Graybiel AM, Liu FC.

Nat Neurosci. 2016 Nov;19(11):1513-1522. doi: 10.1038/nn.4380. Epub 2016 Sep 5.

12.

Foxp2 mutations impair auditory-motor association learning.

Kurt S, Fisher SE, Ehret G.

PLoS One. 2012;7(3):e33130. doi: 10.1371/journal.pone.0033130. Epub 2012 Mar 7.

13.

Motor learning: the FoxP2 puzzle piece.

Teramitsu I, White SA.

Curr Biol. 2008 Apr 22;18(8):R335-7. doi: 10.1016/j.cub.2008.02.048.

14.

Mice carrying a humanized Foxp2 knock-in allele show region-specific shifts of striatal Foxp2 expression levels.

Schreiweis C, Irinopoulou T, Vieth B, Laddada L, Oury F, Burguière E, Enard W, Groszer M.

Cortex. 2019 Jan 30. pii: S0010-9452(19)30027-9. doi: 10.1016/j.cortex.2019.01.008. [Epub ahead of print]

PMID:
30808549
15.

Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits.

Groszer M, Keays DA, Deacon RM, de Bono JP, Prasad-Mulcare S, Gaub S, Baum MG, French CA, Nicod J, Coventry JA, Enard W, Fray M, Brown SD, Nolan PM, Pääbo S, Channon KM, Costa RM, Eilers J, Ehret G, Rawlins JN, Fisher SE.

Curr Biol. 2008 Mar 11;18(5):354-62. doi: 10.1016/j.cub.2008.01.060.

16.

FOXP2 as a molecular window into speech and language.

Fisher SE, Scharff C.

Trends Genet. 2009 Apr;25(4):166-77. doi: 10.1016/j.tig.2009.03.002. Epub 2009 Mar 21. Review.

PMID:
19304338
17.

Human-specific increase of dopaminergic innervation in a striatal region associated with speech and language: A comparative analysis of the primate basal ganglia.

Raghanti MA, Edler MK, Stephenson AR, Wilson LJ, Hopkins WD, Ely JJ, Erwin JM, Jacobs B, Hof PR, Sherwood CC.

J Comp Neurol. 2016 Jul 1;524(10):2117-29. doi: 10.1002/cne.23937. Epub 2015 Dec 29.

18.

Diminished FoxP2 levels affect dopaminergic modulation of corticostriatal signaling important to song variability.

Murugan M, Harward S, Scharff C, Mooney R.

Neuron. 2013 Dec 18;80(6):1464-76. doi: 10.1016/j.neuron.2013.09.021. Epub 2013 Nov 21.

19.

[Language gene].

Takahashi H.

Rinsho Shinkeigaku. 2006 Nov;46(11):848-50. Japanese.

PMID:
17432197
20.

FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder.

Lai CS, Gerrelli D, Monaco AP, Fisher SE, Copp AJ.

Brain. 2003 Nov;126(Pt 11):2455-62. Epub 2003 Jul 22.

PMID:
12876151

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