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Items: 1 to 20 of 119

1.

Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.

Li X, Nadauld L, Ootani A, Corney DC, Pai RK, Gevaert O, Cantrell MA, Rack PG, Neal JT, Chan CW, Yeung T, Gong X, Yuan J, Wilhelmy J, Robine S, Attardi LD, Plevritis SK, Hung KE, Chen CZ, Ji HP, Kuo CJ.

Nat Med. 2014 Jul;20(7):769-77. doi: 10.1038/nm.3585. Epub 2014 May 25.

2.

An Air-Liquid Interface Culture System for 3D Organoid Culture of Diverse Primary Gastrointestinal Tissues.

Li X, Ootani A, Kuo C.

Methods Mol Biol. 2016;1422:33-40. doi: 10.1007/978-1-4939-3603-8_4.

PMID:
27246020
3.

Preparation of Human Primary Colon Tissue-Derived Organoid Using Air Liquid Interface Culture.

Usui T, Sakurai M, Umata K, Yamawaki H, Ohama T, Sato K.

Curr Protoc Toxicol. 2018 Feb 21;75:22.6.1-22.6.7. doi: 10.1002/cptx.40.

PMID:
29512123
4.

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.

Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C.

Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12.

PMID:
25127677
5.

Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer.

Schiavone M, Rampazzo E, Casari A, Battilana G, Persano L, Moro E, Liu S, Leach SD, Tiso N, Argenton F.

Dis Model Mech. 2014 Jul;7(7):883-94. doi: 10.1242/dmm.014969. Epub 2014 May 30.

6.

Epithelial tissues have varying degrees of susceptibility to Kras(G12D)-initiated tumorigenesis in a mouse model.

Ray KC, Bell KM, Yan J, Gu G, Chung CH, Washington MK, Means AL.

PLoS One. 2011 Feb 2;6(2):e16786. doi: 10.1371/journal.pone.0016786.

7.

Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey.

Park JT, Johnson N, Liu S, Levesque M, Wang YJ, Ho H, Huso D, Maitra A, Parsons MJ, Prescott JD, Leach SD.

Oncogene. 2015 May 21;34(21):2801-6. doi: 10.1038/onc.2014.223. Epub 2014 Jul 28.

8.

A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma.

Yamaguchi T, Ikehara S, Nakanishi H, Ikehara Y.

J Pathol. 2014 Oct;234(2):228-38. doi: 10.1002/path.4402. Epub 2014 Aug 4.

PMID:
25042889
9.

Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay.

Park JW, Lee JK, Phillips JW, Huang P, Cheng D, Huang J, Witte ON.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4482-7. doi: 10.1073/pnas.1603645113. Epub 2016 Apr 4.

10.

A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.

Inagawa Y, Yamada K, Yugawa T, Ohno S, Hiraoka N, Esaki M, Shibata T, Aoki K, Saya H, Kiyono T.

Carcinogenesis. 2014 Aug;35(8):1840-6. doi: 10.1093/carcin/bgu112. Epub 2014 May 24.

PMID:
24858378
11.

Development of a functional thyroid model based on an organoid culture system.

Saito Y, Onishi N, Takami H, Seishima R, Inoue H, Hirata Y, Kameyama K, Tsuchihashi K, Sugihara E, Uchino S, Ito K, Kawakubo H, Takeuchi H, Kitagawa Y, Saya H, Nagano O.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):783-789. doi: 10.1016/j.bbrc.2018.02.154. Epub 2018 Feb 19.

PMID:
29470983
12.

Genetic reconstitution of tumorigenesis in primary intestinal cells.

Onuma K, Ochiai M, Orihashi K, Takahashi M, Imai T, Nakagama H, Hippo Y.

Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11127-32. doi: 10.1073/pnas.1221926110. Epub 2013 Jun 17.

13.

Protein-engineered scaffolds for in vitro 3D culture of primary adult intestinal organoids.

DiMarco RL, Dewi RE, Bernal G, Kuo C, Heilshorn SC.

Biomater Sci. 2015 Oct 15;3(10):1376-85. doi: 10.1039/c5bm00108k. Epub 2015 Jul 16.

PMID:
26371971
14.

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.

Matano M, Date S, Shimokawa M, Takano A, Fujii M, Ohta Y, Watanabe T, Kanai T, Sato T.

Nat Med. 2015 Mar;21(3):256-62. doi: 10.1038/nm.3802. Epub 2015 Feb 23.

PMID:
25706875
15.

Human gastric cancer modelling using organoids.

Seidlitz T, Merker SR, Rothe A, Zakrzewski F, von Neubeck C, Grützmann K, Sommer U, Schweitzer C, Schölch S, Uhlemann H, Gaebler AM, Werner K, Krause M, Baretton GB, Welsch T, Koo BK, Aust DE, Klink B, Weitz J, Stange DE.

Gut. 2019 Feb;68(2):207-217. doi: 10.1136/gutjnl-2017-314549. Epub 2018 Apr 27.

16.

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.

Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, DiMaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD.

Mol Cancer Res. 2013 Jun;11(6):638-50. doi: 10.1158/1541-7786.MCR-12-0634-T. Epub 2013 Feb 28.

17.

Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium.

Sato T, Stange DE, Ferrante M, Vries RG, Van Es JH, Van den Brink S, Van Houdt WJ, Pronk A, Van Gorp J, Siersema PD, Clevers H.

Gastroenterology. 2011 Nov;141(5):1762-72. doi: 10.1053/j.gastro.2011.07.050. Epub 2011 Sep 2.

PMID:
21889923
18.

Organoid models of human and mouse ductal pancreatic cancer.

Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, Rivera KD, Wilson JP, Feigin ME, Öhlund D, Handly-Santana A, Ardito-Abraham CM, Ludwig M, Elyada E, Alagesan B, Biffi G, Yordanov GN, Delcuze B, Creighton B, Wright K, Park Y, Morsink FH, Molenaar IQ, Borel Rinkes IH, Cuppen E, Hao Y, Jin Y, Nijman IJ, Iacobuzio-Donahue C, Leach SD, Pappin DJ, Hammell M, Klimstra DS, Basturk O, Hruban RH, Offerhaus GJ, Vries RG, Clevers H, Tuveson DA.

Cell. 2015 Jan 15;160(1-2):324-38. doi: 10.1016/j.cell.2014.12.021. Epub 2014 Dec 31.

19.

Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.

Wiener Z, Band AM, Kallio P, Högström J, Hyvönen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36. doi: 10.1073/pnas.1406444111. Epub 2014 May 13.

20.

Gastrointestinal Epithelial Organoid Cultures from Postsurgical Tissues.

Hahn S, Yoo J.

Methods Mol Biol. 2017 Aug 17. doi: 10.1007/7651_2017_57. [Epub ahead of print]

PMID:
28815516

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