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Items: 1 to 20 of 83

1.

Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell.

Asial I, Cheng YX, Engman H, Dollhopf M, Wu B, Nordlund P, Cornvik T.

Nat Commun. 2013;4:2901. doi: 10.1038/ncomms3901.

PMID:
24352381
2.

[Design and application of high-throughput screening tools: a review].

Tang S, Liang C, Jiang P.

Sheng Wu Gong Cheng Xue Bao. 2012 Jul;28(7):781-8. Review. Chinese.

PMID:
23167190
3.

Stabilizing membrane proteins through protein engineering.

Scott DJ, Kummer L, Tremmel D, Plückthun A.

Curr Opin Chem Biol. 2013 Jun;17(3):427-35. doi: 10.1016/j.cbpa.2013.04.002. Epub 2013 Apr 29. Review.

PMID:
23639904
4.

Affinity-based screening techniques: their impact and benefit to increase the number of high quality leads.

Bergsdorf C, Ottl J.

Expert Opin Drug Discov. 2010 Nov;5(11):1095-107. doi: 10.1517/17460441.2010.524641. Epub 2010 Oct 7. Review.

PMID:
22827747
5.

Directed evolution of proteins for increased stability and expression using yeast display.

Traxlmayr MW, Obinger C.

Arch Biochem Biophys. 2012 Oct 15;526(2):174-80. doi: 10.1016/j.abb.2012.04.022. Epub 2012 May 3. Review.

PMID:
22575387
6.

An integrated approach to extreme thermostabilization and affinity maturation of an antibody.

McConnell AD, Spasojevich V, Macomber JL, Krapf IP, Chen A, Sheffer JC, Berkebile A, Horlick RA, Neben S, King DJ, Bowers PM.

Protein Eng Des Sel. 2013 Feb;26(2):151-64. doi: 10.1093/protein/gzs090. Epub 2012 Nov 19.

PMID:
23173178
7.

The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.

Lee J, Blaber M.

J Mol Biol. 2009 Oct 16;393(1):113-27. doi: 10.1016/j.jmb.2009.08.026. Epub 2009 Aug 18.

PMID:
19695265
8.

Stability engineering of scFvs for the development of bispecific and multivalent antibodies.

Miller BR, Demarest SJ, Lugovskoy A, Huang F, Wu X, Snyder WB, Croner LJ, Wang N, Amatucci A, Michaelson JS, Glaser SM.

Protein Eng Des Sel. 2010 Jul;23(7):549-57. doi: 10.1093/protein/gzq028. Epub 2010 May 10.

PMID:
20457695
9.

A Computational Library Design Protocol for Rapid Improvement of Protein Stability: FRESCO.

Wijma HJ, Fürst MJLJ, Janssen DB.

Methods Mol Biol. 2018;1685:69-85. doi: 10.1007/978-1-4939-7366-8_5.

PMID:
29086304
10.

Engineering a large protein by combined rational and random approaches: stabilizing the Clostridium thermocellum cellobiose phosphorylase.

Ye X, Zhang C, Zhang YH.

Mol Biosyst. 2012 Jun;8(6):1815-23. doi: 10.1039/c2mb05492b. Epub 2012 Apr 17.

PMID:
22511238
11.

Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability.

Wijma HJ, Floor RJ, Janssen DB.

Curr Opin Struct Biol. 2013 Aug;23(4):588-94. doi: 10.1016/j.sbi.2013.04.008. Epub 2013 May 15. Review.

PMID:
23683520
12.

Modulating protein stability - directed evolution strategies for improved protein function.

Socha RD, Tokuriki N.

FEBS J. 2013 Nov;280(22):5582-95. doi: 10.1111/febs.12354. Epub 2013 Jun 18. Review.

13.

Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening.

Seitz T, Thoma R, Schoch GA, Stihle M, Benz J, D'Arcy B, Wiget A, Ruf A, Hennig M, Sterner R.

J Mol Biol. 2010 Nov 5;403(4):562-77. doi: 10.1016/j.jmb.2010.08.048. Epub 2010 Sep 17.

PMID:
20850457
14.

A rapid and effective procedure for screening protease mutants.

Venekei I, Hedstrom L, Rutter WJ.

Protein Eng. 1996 Jan;9(1):85-93.

PMID:
9053907
15.

Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR.

Michaelson JS, Demarest SJ, Miller B, Amatucci A, Snyder WB, Wu X, Huang F, Phan S, Gao S, Doern A, Farrington GK, Lugovskoy A, Joseph I, Bailly V, Wang X, Garber E, Browning J, Glaser SM.

MAbs. 2009 Mar-Apr;1(2):128-41. Epub 2009 Mar 11.

16.

Fine tuning of the specificity of an anti-progesterone antibody by first and second sphere residue engineering.

Dubreuil O, Bossus M, Graille M, Bilous M, Savatier A, Jolivet M, Ménez A, Stura E, Ducancel F.

J Biol Chem. 2005 Jul 1;280(26):24880-7. Epub 2005 May 4.

17.

T cell receptor engineering.

Stone JD, Chervin AS, Aggen DH, Kranz DM.

Methods Enzymol. 2012;503:189-222. doi: 10.1016/B978-0-12-396962-0.00008-2.

PMID:
22230570
18.
19.

Quantitative Y2H screening: cloning and signal peptide engineering of a fungal secretory LacA gene and its application to yeast two-hybrid system as a quantitative reporter.

Kamiya T, Ojima T, Sugimoto K, Nakano H, Kawarasaki Y.

J Biotechnol. 2010 Apr 15;146(4):151-9. doi: 10.1016/j.jbiotec.2010.02.007. Epub 2010 Feb 18.

PMID:
20171251
20.

Ultrahigh-throughput FACS-based screening for directed enzyme evolution.

Yang G, Withers SG.

Chembiochem. 2009 Nov 23;10(17):2704-15. doi: 10.1002/cbic.200900384. Review.

PMID:
19780076

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