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Items: 1 to 20 of 106

1.

Identity, potency, in vivo viability, and scaling up production of lentiviral vector-induced dendritic cells for melanoma immunotherapy.

Pincha M, Sundarasetty BS, Salguero G, Gutzmer R, Garritsen H, Macke L, Schneider A, Lenz D, Figueiredo C, Blasczyk R, Ruggiero E, Schmidt M, von Kalle C, Puff C, Modlich U, von der Leyen H, Wicke DC, Ganser A, Stripecke R.

Hum Gene Ther Methods. 2012 Feb;23(1):38-55. doi: 10.1089/hgtb.2011.170.

PMID:
22428979
2.

Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma.

Sundarasetty BS, Chan L, Darling D, Giunti G, Farzaneh F, Schenck F, Naundorf S, Kuehlcke K, Ruggiero E, Schmidt M, von Kalle C, Rothe M, Hoon DS, Gerasch L, Figueiredo C, Koehl U, Blasczyk R, Gutzmer R, Stripecke R.

Gene Ther. 2015 Sep;22(9):707-20. doi: 10.1038/gt.2015.43. Epub 2015 May 28.

3.

Integrase-defective lentiviral vectors encoding cytokines induce differentiation of human dendritic cells and stimulate multivalent immune responses in vitro and in vivo.

Daenthanasanmak A, Salguero G, Borchers S, Figueiredo C, Jacobs R, Sundarasetty BS, Schneider A, Schambach A, Eiz-Vesper B, Blasczyk R, Weissinger EM, Ganser A, Stripecke R.

Vaccine. 2012 Jul 20;30(34):5118-31. doi: 10.1016/j.vaccine.2012.05.063. Epub 2012 Jun 9.

4.

Preconditioning therapy with lentiviral vector-programmed dendritic cells accelerates the homeostatic expansion of antigen-reactive human T cells in NOD.Rag1-/-.IL-2rγc-/- mice.

Salguero G, Sundarasetty BS, Borchers S, Wedekind D, Eiz-Vesper B, Velaga S, Jirmo AC, Behrens G, Warnecke G, Knöfel AK, Blasczyk R, Mischak-Weissinger E, Ganser A, Stripecke R.

Hum Gene Ther. 2011 Oct;22(10):1209-24. doi: 10.1089/hum.2010.215. Epub 2011 Jul 27.

5.

Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia.

Sundarasetty BS, Singh VK, Salguero G, Geffers R, Rickmann M, Macke L, Borchers S, Figueiredo C, Schambach A, Gullberg U, Provasi E, Bonini C, Ganser A, Woelfel T, Stripecke R.

Hum Gene Ther. 2013 Feb;24(2):220-37. doi: 10.1089/hum.2012.128.

6.

Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines.

Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R.

Mol Ther. 2007 May;15(5):971-80. Epub 2007 Mar 20.

7.

Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells.

Pincha M, Salguero G, Wedekind D, Sundarasetty BS, Lin A, Kasahara N, Brugman MH, Jirmo AC, Modlich U, Gutzmer R, Büsche G, Ganser A, Stripecke R.

Gene Ther. 2011 Aug;18(8):750-64. doi: 10.1038/gt.2011.15. Epub 2011 Mar 17.

9.

Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity.

Tüting T, Steitz J, Brück J, Gambotto A, Steinbrink K, DeLeo AB, Robbins P, Knop J, Enk AH.

J Gene Med. 1999 Nov-Dec;1(6):400-6.

PMID:
10753065
10.

Effective induction of melanoma-antigen-specific CD8+ T cells via Vγ9γδT cell expansion by CD56(high+) Interferon-α-induced dendritic cells.

Nieda M, Terunuma H, Eiraku Y, Deng X, Nicol AJ.

Exp Dermatol. 2015 Jan;24(1):35-41. doi: 10.1111/exd.12581. Epub 2014 Dec 8.

PMID:
25363560
11.

Closing the manufacturing process of dendritic cell vaccines transduced with adenovirus vectors.

Gulen D, Abe F, Maas S, Reed E, Cowan K, Pirruccello S, Wisecarver J, Warkentin P, Northam M, Turken O, Coskun U, Senesac J, Talmadge JE.

Int Immunopharmacol. 2008 Dec 20;8(13-14):1728-36. doi: 10.1016/j.intimp.2008.08.010. Epub 2008 Sep 13.

PMID:
18793758
12.

Lentiviral vector expression of tumour antigens in dendritic cells as an immunotherapeutic strategy.

Lopes L, Fletcher K, Ikeda Y, Collins M.

Cancer Immunol Immunother. 2006 Aug;55(8):1011-6. Epub 2005 Nov 26.

PMID:
16311731
13.

Dendritic cell-directed lentivector vaccine induces antigen-specific immune responses against murine melanoma.

Yang HG, Hu BL, Xiao L, Wang P.

Cancer Gene Ther. 2011 May;18(5):370-80. doi: 10.1038/cgt.2011.13. Epub 2011 Mar 4.

PMID:
21372855
14.

Transduction of dendritic cells by antigen-encoding lentiviral vectors permits antigen processing and MHC class I-dependent presentation.

Zarei S, Leuba F, Arrighi JF, Hauser C, Piguet V.

J Allergy Clin Immunol. 2002 Jun;109(6):988-94.

PMID:
12063529
15.
16.

Generation of lentivirus-induced dendritic cells under GMP-compliant conditions for adaptive immune reconstitution against cytomegalovirus after stem cell transplantation.

Sundarasetty BS, Kloess S, Oberschmidt O, Naundorf S, Kuehlcke K, Daenthanasanmak A, Gerasch L, Figueiredo C, Blasczyk R, Ruggiero E, Fronza R, Schmidt M, von Kalle C, Rothe M, Ganser A, Koehl U, Stripecke R.

J Transl Med. 2015 Jul 22;13:240. doi: 10.1186/s12967-015-0599-5.

17.

Antitumor activity of lentivirus-mediated interleukin -12 gene modified dendritic cells in human lung cancer in vitro.

Ahmed Ali HA, Di J, Mei W, Zhang YC, Li Y, Du ZW, Zhang GZ.

Asian Pac J Cancer Prev. 2014;15(2):611-6.

18.

Activation of monocytes via the CD14 receptor leads to the enhanced lentiviral transduction of immature dendritic cells.

Breckpot K, Corthals J, Heirman C, Bonehill A, Michiels A, Tuyaerts S, De Greef C, Thielemans K.

Hum Gene Ther. 2004 Jun;15(6):562-73.

PMID:
15212715
19.

Potent maturation of monocyte-derived dendritic cells after CD40L lentiviral gene delivery.

Koya RC, Kasahara N, Favaro PM, Lau R, Ta HQ, Weber JS, Stripecke R.

J Immunother. 2003 Sep-Oct;26(5):451-60.

PMID:
12973034
20.

Cryopreservation of adenovirus-transfected dendritic cells (DCs) for clinical use.

Gülen D, Maas S, Julius H, Warkentin P, Britton H, Younos I, Senesac J, Pirruccello SM, Talmadge JE.

Int Immunopharmacol. 2012 May;13(1):61-8. doi: 10.1016/j.intimp.2012.03.009. Epub 2012 Mar 27.

PMID:
22465385

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