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Items: 1 to 20 of 253

1.

TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-kappaB.

Zhang P, Liu J, Xu Q, Harber G, Feng X, Michalek SM, Katz J.

J Biol Chem. 2011 Jul 8;286(27):24159-69. doi: 10.1074/jbc.M110.198085. Epub 2011 May 12.

2.

IL-1R/TLR2 through MyD88 Divergently Modulates Osteoclastogenesis through Regulation of Nuclear Factor of Activated T Cells c1 (NFATc1) and B Lymphocyte-induced Maturation Protein-1 (Blimp1).

Chen Z, Su L, Xu Q, Katz J, Michalek SM, Fan M, Feng X, Zhang P.

J Biol Chem. 2015 Dec 11;290(50):30163-74. doi: 10.1074/jbc.M115.663518. Epub 2015 Oct 19.

3.

Infection of RANKL-primed RAW-D macrophages with Porphyromonas gingivalis promotes osteoclastogenesis in a TNF-α-independent manner.

Kukita A, Ichigi Y, Takigawa I, Watanabe T, Kukita T, Miyamoto H.

PLoS One. 2012;7(6):e38500. doi: 10.1371/journal.pone.0038500. Epub 2012 Jun 18.

4.

NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1.

Yamashita T, Yao Z, Li F, Zhang Q, Badell IR, Schwarz EM, Takeshita S, Wagner EF, Noda M, Matsuo K, Xing L, Boyce BF.

J Biol Chem. 2007 Jun 22;282(25):18245-53. Epub 2007 May 7.

5.

Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-κB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts.

Kassem A, Henning P, Lundberg P, Souza PP, Lindholm C, Lerner UH.

J Biol Chem. 2015 Aug 14;290(33):20147-58. doi: 10.1074/jbc.M115.655787. Epub 2015 Jun 17.

6.

A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis.

Savage JR, Pulsipher A, Rao NV, Kennedy TP, Prestwich GD, Ryan ME, Lee WY.

PLoS One. 2016 Jun 16;11(6):e0157310. doi: 10.1371/journal.pone.0157310. eCollection 2016.

7.

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss.

Papadopoulos G, Weinberg EO, Massari P, Gibson FC 3rd, Wetzler LM, Morgan EF, Genco CA.

J Immunol. 2013 Feb 1;190(3):1148-57. doi: 10.4049/jimmunol.1202511. Epub 2012 Dec 21.

8.

Baicalin inhibits toll-like receptor 2/4 expression and downstream signaling in rat experimental periodontitis.

Sun JY, Li DL, Dong Y, Zhu CH, Liu J, Li JD, Zhou T, Gou JZ, Li A, Zang WJ.

Int Immunopharmacol. 2016 Jul;36:86-93. doi: 10.1016/j.intimp.2016.04.012. Epub 2016 Apr 22.

PMID:
27107801
9.

Interleukin-10 inhibits RANKL-mediated expression of NFATc1 in part via suppression of c-Fos and c-Jun in RAW264.7 cells and mouse bone marrow cells.

Mohamed SG, Sugiyama E, Shinoda K, Taki H, Hounoki H, Abdel-Aziz HO, Maruyama M, Kobayashi M, Ogawa H, Miyahara T.

Bone. 2007 Oct;41(4):592-602. Epub 2007 Jun 13.

PMID:
17627913
10.
11.

The hemoglobin receptor protein of porphyromonas gingivalis inhibits receptor activator NF-kappaB ligand-induced osteoclastogenesis from bone marrow macrophages.

Fujimura Y, Hotokezaka H, Ohara N, Naito M, Sakai E, Yoshimura M, Narita Y, Kitaura H, Yoshida N, Nakayama K.

Infect Immun. 2006 May;74(5):2544-51.

12.

Pim-1 regulates RANKL-induced osteoclastogenesis via NF-κB activation and NFATc1 induction.

Kim K, Kim JH, Youn BU, Jin HM, Kim N.

J Immunol. 2010 Dec 15;185(12):7460-6. doi: 10.4049/jimmunol.1000885. Epub 2010 Nov 10.

13.

Apolipoprotein E inhibits osteoclast differentiation via regulation of c-Fos, NFATc1 and NF-κB.

Kim WS, Kim HJ, Lee ZH, Lee Y, Kim HH.

Exp Cell Res. 2013 Feb 15;319(4):436-46. doi: 10.1016/j.yexcr.2012.12.004. Epub 2012 Dec 12.

PMID:
23246654
14.

Porphyromonas gingivalis exacerbates ligature-induced, RANKL-dependent alveolar bone resorption via differential regulation of Toll-like receptor 2 (TLR2) and TLR4.

Lin J, Bi L, Yu X, Kawai T, Taubman MA, Shen B, Han X.

Infect Immun. 2014 Oct;82(10):4127-34. doi: 10.1128/IAI.02084-14. Epub 2014 Jul 21.

15.

Epigallocatechin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-kappaB signal.

Lee JH, Jin H, Shim HE, Kim HN, Ha H, Lee ZH.

Mol Pharmacol. 2010 Jan;77(1):17-25. doi: 10.1124/mol.109.057877. Epub 2009 Oct 14.

PMID:
19828731
16.

Inhibition of receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclast formation by pyrroloquinoline quinine (PQQ).

Odkhuu E, Koide N, Haque A, Tsolmongyn B, Naiki Y, Hashimoto S, Komatsu T, Yoshida T, Yokochi T.

Immunol Lett. 2012 Feb 29;142(1-2):34-40. doi: 10.1016/j.imlet.2011.12.001. Epub 2011 Dec 13.

PMID:
22193059
17.

TLR2-dependent inflammatory response to Porphyromonas gingivalis is MyD88 independent, whereas MyD88 is required to clear infection.

Burns E, Eliyahu T, Uematsu S, Akira S, Nussbaum G.

J Immunol. 2010 Feb 1;184(3):1455-62. doi: 10.4049/jimmunol.0900378. Epub 2009 Dec 30.

18.

Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis.

Jules J, Zhang P, Ashley JW, Wei S, Shi Z, Liu J, Michalek SM, Feng X.

J Biol Chem. 2012 May 4;287(19):15728-38. doi: 10.1074/jbc.M111.296228. Epub 2012 Mar 13.

20.

Inhibition of RANKL-stimulated osteoclast differentiation by Schisandra chinensis through down-regulation of NFATc1 and c-fos expression.

Kim EJ, Lee H, Kim MH, Yang WM.

BMC Complement Altern Med. 2018 Oct 1;18(1):270. doi: 10.1186/s12906-018-2331-5.

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