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Items: 1 to 20 of 109

1.

In vitro metabolism, glutathione conjugation, and CYP isoform specificity of epoxidation of 4-vinylphenol.

Zhang F, Lowe ER, Rick DL, Qiu X, Leibold E, Cruzan G, Bartels MJ.

Xenobiotica. 2011 Jan;41(1):6-23. doi: 10.3109/00498254.2010.523735. Epub 2010 Oct 7.

PMID:
20925585
2.

Metabolism of the styrene metabolite 4-vinylphenol by rat and mouse liver and lung.

Carlson GP, Perez Rivera AA, Mantick NA.

J Toxicol Environ Health A. 2001 Aug 10;63(7):541-51.

PMID:
11497334
3.
5.

Benzene metabolism by human liver microsomes in relation to cytochrome P450 2E1 activity.

Seaton MJ, Schlosser PM, Bond JA, Medinsky MA.

Carcinogenesis. 1994 Sep;15(9):1799-806.

PMID:
7923572
7.

Differences in cytochrome P450-mediated biotransformation of 1,2-dichlorobenzene by rat and man: implications for human risk assessment.

Hissink AM, Oudshoorn MJ, Van Ommen B, Haenen GR, Van Bladeren PJ.

Chem Res Toxicol. 1996 Dec;9(8):1249-56.

PMID:
8951226
8.

Metabolic activation of a pentafluorophenylethylamine derivative: formation of glutathione conjugates in vitro in the rat.

Shang J, Xu S, Teffera Y, Doss GA, Stearns RA, Edmonson S, Beconi MG.

Xenobiotica. 2005 Jul;35(7):697-713.

PMID:
16316929
9.

NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.

Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS.

Chem Res Toxicol. 2007 Nov;20(11):1649-57. Epub 2007 Oct 2.

PMID:
17907785
10.
11.

Covalent binding of catechol estrogens to glutathione catalyzed by horseradish peroxidase, lactoperoxidase, or rat liver microsomes.

Cao K, Devanesan PD, Ramanathan R, Gross ML, Rogan EG, Cavalieri EL.

Chem Res Toxicol. 1998 Aug;11(8):917-24.

PMID:
9705754
12.

Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission.

Kassahun K, Pearson PG, Tang W, McIntosh I, Leung K, Elmore C, Dean D, Wang R, Doss G, Baillie TA.

Chem Res Toxicol. 2001 Jan;14(1):62-70.

PMID:
11170509
13.

Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways.

Han X, Szostek B, Yang CH, Cheatham SF, Mingoia RT, Nabb DL, Gannon SA, Himmelstein MW, Jepson GW.

Drug Metab Dispos. 2011 Jul;39(7):1288-93. doi: 10.1124/dmd.111.038299. Epub 2011 Apr 14.

PMID:
21493824
14.

CYP2E1-dependent bioactivation of 1,1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates.

Dowsley TF, Ulreich JB, Bolton JL, Park SS, Forkert PG.

Toxicol Appl Pharmacol. 1996 Jul;139(1):42-8.

PMID:
8685907
15.

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis.

Saghir SA, Zhang F, Rick DL, Kan L, Bus JS, Bartels MJ.

Regul Toxicol Pharmacol. 2010 Jul-Aug;57(2-3):129-35. doi: 10.1016/j.yrtph.2010.01.003. Epub 2010 Jan 22.

PMID:
20096743
16.

Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy.

Hill BA, Kleiner HE, Ryan EA, Dulik DM, Monks TJ, Lau SS.

Chem Res Toxicol. 1993 Jul-Aug;6(4):459-69.

PMID:
8374043
17.

The metabolism of beta-chloroprene: preliminary in-vitro studies using liver microsomes.

Himmelstein MW, Carpenter SC, Hinderliter PM, Snow TA, Valentine R.

Chem Biol Interact. 2001 Jun 1;135-136:267-84.

PMID:
11397396
18.

Characterization of glutathione conjugates derived from reactive metabolites of bakuchiol.

Chi M, Peng Y, Zheng J.

Chem Biol Interact. 2016 Jan 25;244:178-86. doi: 10.1016/j.cbi.2015.12.009. Epub 2015 Dec 19.

PMID:
26712081
19.

Formation of glutathione conjugates during oxidation of eugenol by microsomal fractions of rat liver and lung.

Thompson D, Constantin-Teodosiu D, Egestad B, Mickos H, Moldéus P.

Biochem Pharmacol. 1990 May 15;39(10):1587-95.

PMID:
2337416
20.

Metabolism of caffeic acid by isolated rat hepatocytes and subcellular fractions.

Moridani MY, Scobie H, O'Brien PJ.

Toxicol Lett. 2002 Jul 21;133(2-3):141-51.

PMID:
12119122

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