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Items: 1 to 20 of 89

1.

Induction of distinct TLR2-mediated proinflammatory and proadhesive signaling pathways in response to Porphyromonas gingivalis fimbriae.

Hajishengallis G, Wang M, Liang S.

J Immunol. 2009 Jun 1;182(11):6690-6. doi: 10.4049/jimmunol.0900524.

2.
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Porphyromonas gingivalis fimbriae proactively modulate beta2 integrin adhesive activity and promote binding to and internalization by macrophages.

Hajishengallis G, Wang M, Harokopakis E, Triantafilou M, Triantafilou K.

Infect Immun. 2006 Oct;74(10):5658-66.

4.

Intracellular signaling and cytokine induction upon interactions of Porphyromonas gingivalis fimbriae with pattern-recognition receptors.

Hajishengallis G, Sojar H, Genco RJ, DeNardin E.

Immunol Invest. 2004 May;33(2):157-72.

PMID:
15195695
5.

Porphyromonas gingivalis Stimulates TLR2-PI3K Signaling to Escape Immune Clearance and Induce Bone Resorption Independently of MyD88.

Makkawi H, Hoch S, Burns E, Hosur K, Hajishengallis G, Kirschning CJ, Nussbaum G.

Front Cell Infect Microbiol. 2017 Aug 8;7:359. doi: 10.3389/fcimb.2017.00359. eCollection 2017.

6.

Mechanism and implications of CXCR4-mediated integrin activation by Porphyromonas gingivalis.

Hajishengallis G, McIntosh ML, Nishiyama SI, Yoshimura F.

Mol Oral Microbiol. 2013 Aug;28(4):239-49. doi: 10.1111/omi.12021. Epub 2013 Jan 21.

7.

Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide.

Martin M, Schifferle RE, Cuesta N, Vogel SN, Katz J, Michalek SM.

J Immunol. 2003 Jul 15;171(2):717-25.

9.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

10.

TLR2-dependent inflammatory response to Porphyromonas gingivalis is MyD88 independent, whereas MyD88 is required to clear infection.

Burns E, Eliyahu T, Uematsu S, Akira S, Nussbaum G.

J Immunol. 2010 Feb 1;184(3):1455-62. doi: 10.4049/jimmunol.0900378. Epub 2009 Dec 30.

11.

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss.

Papadopoulos G, Weinberg EO, Massari P, Gibson FC 3rd, Wetzler LM, Morgan EF, Genco CA.

J Immunol. 2013 Feb 1;190(3):1148-57. doi: 10.4049/jimmunol.1202511. Epub 2012 Dec 21.

12.

Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus.

Hajishengallis G, Tapping RI, Harokopakis E, Nishiyama S, Ratti P, Schifferle RE, Lyle EA, Triantafilou M, Triantafilou K, Yoshimura F.

Cell Microbiol. 2006 Oct;8(10):1557-70.

PMID:
16984411
13.

Bacterial fimbriae stimulate proinflammatory activation in the endothelium through distinct TLRs.

Davey M, Liu X, Ukai T, Jain V, Gudino C, Gibson FC 3rd, Golenbock D, Visintin A, Genco CA.

J Immunol. 2008 Feb 15;180(4):2187-95.

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15.

Increases in IL-33 production by fimbriae and lipopeptide from Porphyromonas gingivalis in mouse bone marrow-derived dendritic cells via Toll-like receptor 2.

Tada H, Suzuki R, Nemoto E, Shimauchi H, Matsushita K, Takada H.

Biomed Res. 2017;38(3):189-195. doi: 10.2220/biomedres.38.189.

16.

Porphyromonas gingivalis interactions with complement receptor 3 (CR3): innate immunity or immune evasion?

Hajishengallis G, Harokopakis E.

Front Biosci. 2007 May 1;12:4547-57. Review.

PMID:
17485396
17.

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.

Santos-Sierra S, Deshmukh SD, Kalnitski J, K├╝enzi P, Wymann MP, Golenbock DT, Henneke P.

EMBO J. 2009 Jul 22;28(14):2018-27. doi: 10.1038/emboj.2009.158. Epub 2009 Jul 2.

18.

Human gingival epithelial cells produce chemotactic factors interleukin-8 and monocyte chemoattractant protein-1 after stimulation with Porphyromonas gingivalis via toll-like receptor 2.

Kusumoto Y, Hirano H, Saitoh K, Yamada S, Takedachi M, Nozaki T, Ozawa Y, Nakahira Y, Saho T, Ogo H, Shimabukuro Y, Okada H, Murakami S.

J Periodontol. 2004 Mar;75(3):370-9.

PMID:
15088874
19.

Peptide mapping of bacterial fimbrial epitopes interacting with pattern recognition receptors.

Hajishengallis G, Ratti P, Harokopakis E.

J Biol Chem. 2005 Nov 25;280(47):38902-13. Epub 2005 Aug 29.

20.

Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway.

Ogawa T, Asai Y, Hashimoto M, Takeuchi O, Kurita T, Yoshikai Y, Miyake K, Akira S.

Int Immunol. 2002 Nov;14(11):1325-32.

PMID:
12407023

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