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Items: 1 to 20 of 120

1.

Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Sandercock LE, Hahn JN, Li L, Luchman HA, Giesbrecht JL, Peterson LA, Jirik FR.

Carcinogenesis. 2008 Apr;29(4):866-74. doi: 10.1093/carcin/bgn030. Epub 2008 Feb 14.

PMID:
18281247
3.

O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke.

Christmann M, Kaina B.

Mutat Res. 2012 Aug 1;736(1-2):64-74. doi: 10.1016/j.mrfmmm.2011.06.004. Epub 2011 Jun 14. Review.

PMID:
21708177
4.
5.

Acute in vivo treatment with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone does not alter base excision repair activities in murine lung and liver.

Gupta N, Curtis RM, Mulder JE, Massey TE.

DNA Repair (Amst). 2013 Dec;12(12):1031-6. doi: 10.1016/j.dnarep.2013.09.009. Epub 2013 Oct 29.

PMID:
24182517
6.
7.
8.

O6-methylguanine-DNA methyltransferase deficiency in developing brain: implications for brain tumorigenesis.

Bobola MS, Blank A, Berger MS, Silber JR.

DNA Repair (Amst). 2007 Aug 1;6(8):1127-33. Epub 2007 May 17.

9.

Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins.

Bugni JM, Meira LB, Samson LD.

Oncogene. 2009 Feb 5;28(5):734-41. doi: 10.1038/onc.2008.426. Epub 2008 Nov 24.

11.
12.

K-ras mutations in lung tumors from A/J and A/J x TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate.

Matzinger SA, Crist KA, Stoner GD, Anderson MW, Pereira MA, Steele VE, Kelloff GJ, Lubet RA, You M.

Carcinogenesis. 1995 Oct;16(10):2487-92.

PMID:
7586156
14.
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17.

The L84F polymorphism in the O6-Methylguanine-DNA-Methyltransferase (MGMT) gene is associated with increased hypoxanthine phosphoribosyltransferase (HPRT) mutant frequency in lymphocytes of tobacco smokers.

Hill CE, Wickliffe JK, Guerin AT, Kinslow CJ, Wolfe KJ, Ammenheuser MM, Abdel-Rahman SZ.

Pharmacogenet Genomics. 2007 Sep;17(9):743-53.

PMID:
17700363
19.

DNA adduct formation from tobacco-specific N-nitrosamines.

Hecht SS.

Mutat Res. 1999 Mar 8;424(1-2):127-42. Review.

PMID:
10064856
20.

K-ras gene sequence effects on the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-DNA adducts.

Ziegel R, Shallop A, Jones R, Tretyakova N.

Chem Res Toxicol. 2003 Apr;16(4):541-50.

PMID:
12703972

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