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Items: 1 to 20 of 468

1.

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

Celie PH, Klaassen RV, van Rossum-Fikkert SE, van Elk R, van Nierop P, Smit AB, Sixma TK.

J Biol Chem. 2005 Jul 15;280(28):26457-66. Epub 2005 May 16.

2.

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors.

Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, Sixma TK.

Nature. 2001 May 17;411(6835):269-76.

PMID:
11357122
3.

The 2.7 A structure of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

Brejc K, van Dijk WJ, Smit AB, Sixma TK.

Novartis Found Symp. 2002;245:22-9; discussion 29-32, 165-8. Review.

PMID:
12027010
4.

Structure and function of AChBP, homologue of the ligand-binding domain of the nicotinic acetylcholine receptor.

Smit AB, Brejc K, Syed N, Sixma TK.

Ann N Y Acad Sci. 2003 Sep;998:81-92. Review.

PMID:
14592865
5.

Insight in nAChR subtype selectivity from AChBP crystal structures.

Rucktooa P, Smit AB, Sixma TK.

Biochem Pharmacol. 2009 Oct 1;78(7):777-87. doi: 10.1016/j.bcp.2009.06.098. Epub 2009 Jul 1. Review.

PMID:
19576182
6.

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures.

Celie PH, van Rossum-Fikkert SE, van Dijk WJ, Brejc K, Smit AB, Sixma TK.

Neuron. 2004 Mar 25;41(6):907-14.

7.

Molecular modelling of the GABAA ion channel protein.

Campagna-Slater V, Weaver DF.

J Mol Graph Model. 2007 Jan;25(5):721-30. Epub 2006 Jun 17.

PMID:
16877018
8.

Acetylcholine-binding proteins: functional and structural homologs of nicotinic acetylcholine receptors.

Smit AB, Celie PH, Kasheverov IE, Mordvintsev DY, van Nierop P, Bertrand D, Tsetlin V, Sixma TK.

J Mol Neurosci. 2006;30(1-2):9-10.

PMID:
17192605
9.

A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors.

Xiu X, Hanek AP, Wang J, Lester HA, Dougherty DA.

J Biol Chem. 2005 Dec 16;280(50):41655-66. Epub 2005 Oct 10.

10.

Circular dichroism studies of extracellular domains of human nicotinic acetylcholine receptors provide an insight into their structure.

Zouridakis M, Kostelidou K, Sotiriadis A, Stergiou C, Eliopoulos E, Poulas K, Tzartos SJ.

Int J Biol Macromol. 2007 Oct 1;41(4):423-9. Epub 2007 Jun 8.

PMID:
17659334
11.

A model for short alpha-neurotoxin bound to nicotinic acetylcholine receptor from Torpedo californica: comparison with long-chain alpha-neurotoxins and alpha-conotoxins.

Mordvintsev DY, Polyak YL, Levtsova OV, Tourleigh YV, Kasheverov IE, Shaitan KV, Utkin YN, Tsetlin VI.

Comput Biol Chem. 2005 Dec;29(6):398-411. Epub 2005 Nov 11.

PMID:
16290328
12.

Polypeptide and peptide toxins, magnifying lenses for binding sites in nicotinic acetylcholine receptors.

Tsetlin V, Utkin Y, Kasheverov I.

Biochem Pharmacol. 2009 Oct 1;78(7):720-31. doi: 10.1016/j.bcp.2009.05.032. Epub 2009 Jun 6. Review.

PMID:
19501053
14.

Mechanisms of channel gating of the ligand-gated ion channel superfamily inferred from protein structure.

Absalom NL, Lewis TM, Schofield PR.

Exp Physiol. 2004 Mar;89(2):145-53. Epub 2004 Feb 17. Review.

15.

Multiple interaction regions in the orthosteric ligand binding domain of the α7 neuronal nicotinic acetylcholine receptor.

Xiao Y, Hammond PS, Mazurov AA, Yohannes D.

J Chem Inf Model. 2012 Nov 26;52(11):3064-73. doi: 10.1021/ci3001953. Epub 2012 Nov 6.

PMID:
23092444
16.

Docking to flexible nicotinic acetylcholine receptors: a validation study using the acetylcholine binding protein.

Sander T, Bruun AT, Balle T.

J Mol Graph Model. 2010 Nov;29(3):415-24. doi: 10.1016/j.jmgm.2010.08.004. Epub 2010 Sep 29.

PMID:
20884263
17.

Molecular recognition of neonicotinoid insecticides: the determinants of life or death.

Tomizawa M, Casida JE.

Acc Chem Res. 2009 Feb 17;42(2):260-9. doi: 10.1021/ar800131p. Review.

PMID:
19053239
18.

A glia-derived acetylcholine-binding protein that modulates synaptic transmission.

Smit AB, Syed NI, Schaap D, van Minnen J, Klumperman J, Kits KS, Lodder H, van der Schors RC, van Elk R, Sorgedrager B, Brejc K, Sixma TK, Geraerts WP.

Nature. 2001 May 17;411(6835):261-8.

PMID:
11357121
19.

Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry.

Shi J, Koeppe JR, Komives EA, Taylor P.

J Biol Chem. 2006 Apr 28;281(17):12170-7. Epub 2006 Feb 16.

20.

Refined structure of the nicotinic acetylcholine receptor at 4A resolution.

Unwin N.

J Mol Biol. 2005 Mar 4;346(4):967-89. Epub 2005 Jan 25.

PMID:
15701510

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