Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 172

1.

A phospholipid sensor controls mechanogating of the K+ channel TREK-1.

Chemin J, Patel AJ, Duprat F, Lauritzen I, Lazdunski M, Honoré E.

EMBO J. 2005 Jan 12;24(1):44-53. Epub 2004 Dec 2.

2.

An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.

Honoré E, Maingret F, Lazdunski M, Patel AJ.

EMBO J. 2002 Jun 17;21(12):2968-76.

3.

Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids.

Chemin J, Patel AJ, Delmas P, Sachs F, Lazdunski M, Honore E.

Curr Top Membr. 2007;59:155-70. doi: 10.1016/S1063-5823(06)59007-6. Epub 2007 Apr 17.

PMID:
25168137
4.

Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton.

Lauritzen I, Chemin J, Honoré E, Jodar M, Guy N, Lazdunski M, Jane Patel A.

EMBO Rep. 2005 Jul;6(7):642-8.

5.

Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel.

Maingret F, Honoré E, Lazdunski M, Patel AJ.

Biochem Biophys Res Commun. 2002 Mar 29;292(2):339-46.

PMID:
11906167
6.

Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel.

Maingret F, Patel AJ, Lesage F, Lazdunski M, Honoré E.

J Biol Chem. 1999 Sep 17;274(38):26691-6.

7.

Molecular mechanisms underlying membrane-potential-mediated regulation of neuronal K2P2.1 channels.

Segal-Hayoun Y, Cohen A, Zilberberg N.

Mol Cell Neurosci. 2010 Jan;43(1):117-26. doi: 10.1016/j.mcn.2009.10.002. Epub 2009 Oct 24.

PMID:
19837167
8.

Identification of the large-conductance background K+ channel in mouse B cells as TREK-2.

Zheng H, Nam JH, Pang B, Shin DH, Kim JS, Chun YS, Park JW, Bang H, Kim WK, Earm YE, Kim SJ.

Am J Physiol Cell Physiol. 2009 Jul;297(1):C188-97. doi: 10.1152/ajpcell.00052.2009. Epub 2009 May 13.

9.

Identification of native rat cerebellar granule cell currents due to background K channel KCNK5 (TASK-2).

Cotten JF, Zou HL, Liu C, Au JD, Yost CS.

Brain Res Mol Brain Res. 2004 Sep 28;128(2):112-20.

PMID:
15363886
10.

Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1: comparisons with structural models.

Maksaev G, Milac A, Anishkin A, Guy HR, Sukharev S.

Channels (Austin). 2011 Jan-Feb;5(1):34-42. Epub 2011 Jan 1.

11.

Angiotensin II inhibits native bTREK-1 K+ channels through a PLC-, kinase C-, and PIP2-independent pathway requiring ATP hydrolysis.

Liu H, Enyeart JA, Enyeart JJ.

Am J Physiol Cell Physiol. 2007 Aug;293(2):C682-95. Epub 2007 May 9.

12.

The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle.

Xian Tao Li, Dyachenko V, Zuzarte M, Putzke C, Preisig-Müller R, Isenberg G, Daut J.

Cardiovasc Res. 2006 Jan;69(1):86-97. Epub 2005 Oct 24.

PMID:
16248991
13.

External Ba2+ block of the two-pore domain potassium channel TREK-1 defines conformational transition in its selectivity filter.

Ma XY, Yu JM, Zhang SZ, Liu XY, Wu BH, Wei XL, Yan JQ, Sun HL, Yan HT, Zheng JQ.

J Biol Chem. 2011 Nov 18;286(46):39813-22. doi: 10.1074/jbc.M111.264788. Epub 2011 Sep 29.

14.

Up- and down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids.

Chemin J, Patel AJ, Duprat F, Sachs F, Lazdunski M, Honore E.

Pflugers Arch. 2007 Oct;455(1):97-103. Epub 2007 Mar 24.

PMID:
17384962
15.

K(+) efflux through two-pore domain K(+) channels is required for mouse embryonic development.

Hur CG, Kim EJ, Cho SK, Cho YW, Yoon SY, Tak HM, Kim CW, Choe C, Han J, Kang D.

Reproduction. 2012 May;143(5):625-36. doi: 10.1530/REP-11-0225. Epub 2012 Mar 14.

PMID:
22419831
16.

AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels.

Sandoz G, Thümmler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F.

EMBO J. 2006 Dec 13;25(24):5864-72. Epub 2006 Nov 16.

17.

TWIK-related two-pore domain potassium channel TREK-1 in carotid endothelium of normotensive and hypertensive mice.

Pokojski S, Busch C, Grgic I, Kacik M, Salman W, Preisig-Müller R, Heyken WT, Daut J, Hoyer J, Köhler R.

Cardiovasc Res. 2008 Jul 1;79(1):80-8. doi: 10.1093/cvr/cvn069. Epub 2008 Mar 13. Retraction in: Pokojski S, Busch C, Grgic I, Kacik M, Salman W, Preisig-Müller R, Heyken WT, Daut J, Hoyer J, Köhler R. Cardiovasc Res. 2008 Nov 1;80(2):320.

PMID:
18339646
18.

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.

Aryal P, Jarerattanachat V, Clausen MV, Schewe M, McClenaghan C, Argent L, Conrad LJ, Dong YY, Pike ACW, Carpenter EP, Baukrowitz T, Sansom MSP, Tucker SJ.

Structure. 2017 May 2;25(5):708-718.e2. doi: 10.1016/j.str.2017.03.006. Epub 2017 Apr 6.

19.

A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues.

Cohen A, Ben-Abu Y, Hen S, Zilberberg N.

J Biol Chem. 2008 Jul 11;283(28):19448-55. doi: 10.1074/jbc.M801273200. Epub 2008 May 12.

20.

Properties of single two-pore domain TREK-2 channels expressed in mammalian cells.

Kang D, Choe C, Cavanaugh E, Kim D.

J Physiol. 2007 Aug 15;583(Pt 1):57-69. Epub 2007 May 31.

Supplemental Content

Support Center