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Items: 1 to 20 of 442

1.

Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.

Miyaki M, Iijima T, Hosono K, Ishii R, Yasuno M, Mori T, Toi M, Hishima T, Shitara N, Tamura K, Utsunomiya J, Kobayashi N, Kuroki T, Iwama T.

Cancer Res. 2000 Nov 15;60(22):6311-3.

2.

Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.

Entius MM, Keller JJ, Westerman AM, van Rees BP, van Velthuysen ML, de Goeij AF, Wilson JH, Giardiello FM, Offerhaus GJ.

J Clin Pathol. 2001 Feb;54(2):126-31.

3.

Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence.

Wang ZJ, Ellis I, Zauber P, Iwama T, Marchese C, Talbot I, Xue WH, Yan ZY, Tomlinson I.

J Pathol. 1999 May;188(1):9-13.

PMID:
10398133
4.

Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.

Gruber SB, Entius MM, Petersen GM, Laken SJ, Longo PA, Boyer R, Levin AM, Mujumdar UJ, Trent JM, Kinzler KW, Vogelstein B, Hamilton SR, Polymeropoulos MH, Offerhaus GJ, Giardiello FM.

Cancer Res. 1998 Dec 1;58(23):5267-70.

5.

De novo germline mutation in the serine-threonine kinase STK11/LKB1 gene associated with Peutz-Jeghers syndrome.

Hernan I, Roig I, Martin B, Gamundi MJ, Martinez-Gimeno M, Carballo M.

Clin Genet. 2004 Jul;66(1):58-62.

PMID:
15200509
6.

Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis.

Wei C, Amos CI, Stephens LC, Campos I, Deng JM, Behringer RR, Rashid A, Frazier ML.

Cancer Res. 2005 Dec 15;65(24):11297-303.

7.

Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.

Miyoshi H, Nakau M, Ishikawa TO, Seldin MF, Oshima M, Taketo MM.

Cancer Res. 2002 Apr 15;62(8):2261-6.

8.

[Peutz-Jeghers syndrome].

Miyaki M.

Nihon Rinsho. 2000 Jul;58(7):1400-4. Review. Japanese.

PMID:
10921312
9.

Identification of molecular alterations in gastrointestinal carcinomas and dysplastic hamartomas in Peutz-Jeghers syndrome.

Korsse SE, Biermann K, Offerhaus GJ, Wagner A, Dekker E, Mathus-Vliegen EM, Kuipers EJ, van Leerdam ME, van Veelen W.

Carcinogenesis. 2013 Jul;34(7):1611-9. doi: 10.1093/carcin/bgt068. Epub 2013 Feb 20.

PMID:
23430953
10.

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity.

Mehenni H, Gehrig C, Nezu J, Oku A, Shimane M, Rossier C, Guex N, Blouin JL, Scott HS, Antonarakis SE.

Am J Hum Genet. 1998 Dec;63(6):1641-50.

11.
12.

STK11/LKB1 germline mutations in the first Peutz-Jeghers syndrome patients identified in Slovakia.

Bartosova Z, Zavodna K, Krivulcik T, Usak J, Mlkva I, Kruzliak T, Hromec J, Usakova V, Kopecka I, Veres P, Bartosova Z, Bujalkova M.

Neoplasma. 2007;54(2):101-7.

PMID:
17319781
13.

The hamartoma-adenoma-carcinoma sequence.

Bosman FT.

J Pathol. 1999 May;188(1):1-2.

PMID:
10398131
14.

Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/-p53-/- compound mutant mice.

Takeda H, Miyoshi H, Kojima Y, Oshima M, Taketo MM.

Oncogene. 2006 Mar 16;25(12):1816-20.

PMID:
16278673
15.

Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression.

Ma Y, Zhang G, Fu X, Xia O, Zhan C, Li L, Wang Z, Wu B.

Oncol Rep. 2010 Jun;23(6):1569-76.

PMID:
20428811
16.

Germline mutations of the STK11 gene in Korean Peutz-Jeghers syndrome patients.

Yoon KA, Ku JL, Choi HS, Heo SC, Jeong SY, Park YJ, Kim NK, Kim JC, Jung PM, Park JG.

Br J Cancer. 2000 Apr;82(8):1403-6.

17.

Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families.

Westerman AM, Entius MM, Boor PP, Koole R, de Baar E, Offerhaus GJ, Lubinski J, Lindhout D, Halley DJ, de Rooij FW, Wilson JH.

Hum Mutat. 1999;13(6):476-81.

PMID:
10408777
18.

Mapping of a translocation breakpoint in a Peutz-Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11-negative PJS cases.

Hearle N, Lucassen A, Wang R, Lim W, Ross F, Wheeler R, Moore I, Shipley J, Houlston R.

Genes Chromosomes Cancer. 2004 Oct;41(2):163-9.

PMID:
15287029
19.

Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer.

Ylikorkala A, Avizienyte E, Tomlinson IP, Tiainen M, Roth S, Loukola A, Hemminki A, Johansson M, Sistonen P, Markie D, Neale K, Phillips R, Zauber P, Twama T, Sampson J, Järvinen H, Mäkelä TP, Aaltonen LA.

Hum Mol Genet. 1999 Jan;8(1):45-51.

PMID:
9887330
20.

Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome.

Esteller M, Avizienyte E, Corn PG, Lothe RA, Baylin SB, Aaltonen LA, Herman JG.

Oncogene. 2000 Jan 6;19(1):164-8.

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