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Items: 1 to 20 of 234


SGK1, the New Player in the Game of Resistance: Chemo-Radio Molecular Target and Strategy for Inhibition.

Talarico C, Dattilo V, D'Antona L, Menniti M, Bianco C, Ortuso F, Alcaro S, Schenone S, Perrotti N, Amato R.

Cell Physiol Biochem. 2016;39(5):1863-1876. Epub 2016 Oct 24. Review.


Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxia.

Matschke J, Wiebeck E, Hurst S, Rudner J, Jendrossek V.

Radiat Oncol. 2016 Jun 1;11:75. doi: 10.1186/s13014-016-0647-1.


SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism.

Hoang B, Shi Y, Frost PJ, Mysore V, Bardeleben C, Lichtenstein A.

Mol Cancer Res. 2016 Apr;14(4):397-407. doi: 10.1158/1541-7786.MCR-15-0422. Epub 2016 Feb 11.


Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation.

Monsivais D, Dyson MT, Yin P, Navarro A, Coon JS 5th, Pavone ME, Bulun SE.

Fertil Steril. 2016 May;105(5):1266-73. doi: 10.1016/j.fertnstert.2016.01.012. Epub 2016 Jan 28.


Serum and glucocorticoid kinase 1 promoted the growth and migration of non-small cell lung cancer cells.

Xiaobo Y, Qiang L, Xiong Q, Zheng R, Jianhua Z, Zhifeng L, Yijiang S, Zheng J.

Gene. 2016 Jan 15;576(1 Pt 2):339-46. doi: 10.1016/j.gene.2015.10.072. Epub 2015 Nov 11.


Common Variants in Serum/Glucocorticoid Regulated Kinase 1 (SGK1) and Blood Pressure Responses to Dietary Sodium or Potassium Interventions: A family-Based Association Study.

Chu C, Wang Y, Wang M, Mu JJ, Liu FQ, Wang L, Ren KY, Wang D, Yuan ZY.

Kidney Blood Press Res. 2015;40(4):424-34. doi: 10.1159/000368518. Epub 2015 Jul 31.


Serum- and Glucocorticoid-Inducible Kinase 1 Confers Protection in Cell-Based and in In Vivo Neurotoxin Models via the c-Jun N-Terminal Kinase Signaling Pathway.

Iqbal S, Howard S, LoGrasso PV.

Mol Cell Biol. 2015 Jun 1;35(11):1992-2006. doi: 10.1128/MCB.01510-14. Epub 2015 Mar 30.


Expression of glucocorticoid inducible genes is associated with reductions in cornu ammonis and dentate gyrus volumes in patients with major depressive disorder.

Frodl T, Carballedo A, Frey EM, O'Keane V, Skokauskas N, Morris D, Gill M, Hughes MM, Harkin A, Connor T.

Dev Psychopathol. 2014 Nov;26(4 Pt 2):1209-17. doi: 10.1017/S0954579414000972.


Serum and glucocorticoid-regulated kinase 1 promotes vascular smooth muscle cell proliferation via regulation of β-catenin dynamics.

Zhong W, Oguljahan B, Xiao Y, Nelson J, Hernandez L, Garcia-Barrio M, Francis SC.

Cell Signal. 2014 Dec;26(12):2765-72. doi: 10.1016/j.cellsig.2014.08.002. Epub 2014 Aug 22.


Serum glucocorticoid inducible kinase (SGK)-1 protects endothelial cells against oxidative stress and apoptosis induced by hyperglycaemia.

Ferrelli F, Pastore D, Capuani B, Lombardo MF, Blot-Chabaud M, Coppola A, Basello K, Galli A, Donadel G, Romano M, Caratelli S, Pacifici F, Arriga R, Di Daniele N, Sbraccia P, Sconocchia G, Bellia A, Tesauro M, Federici M, Della-Morte D, Lauro D.

Acta Diabetol. 2015 Feb;52(1):55-64. doi: 10.1007/s00592-014-0600-4. Epub 2014 Jun 25.


A gene-based analysis of variants in the serum/glucocorticoid regulated kinase (SGK) genes with blood pressure responses to sodium intake: the GenSalt Study.

Li C, Yang X, He J, Hixson JE, Gu D, Rao DC, Shimmin LC, Huang J, Gu CC, Chen J, Li J, Kelly TN.

PLoS One. 2014 May 30;9(5):e98432. doi: 10.1371/journal.pone.0098432. eCollection 2014.


Revealing the role of SGK1 in the dynamics of medulloblastoma using a mathematical model.

Kawka J, Sturm D, Pleier S, Pfister S, Marciniak-Czochra A.

J Theor Biol. 2014 Aug 7;354:105-12. doi: 10.1016/j.jtbi.2014.03.028. Epub 2014 Mar 28.


Urinary serum- and glucocorticoid-inducible kinase SGK1 reflects renal injury in patients with immunoglobulin A nephropathy.

Lu X, Li M, Zhou L, Jiang H, Wang H, Chen J.

Nephrology (Carlton). 2014 Jun;19(6):307-17. doi: 10.1111/nep.12225.


Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death.

Brickley DR, Agyeman AS, Kopp RF, Hall BA, Harbeck MC, Belova L, Volden PA, Wu W, Roe MW, Conzen SD.

J Biol Chem. 2013 Nov 8;288(45):32708-19. doi: 10.1074/jbc.M113.507210. Epub 2013 Sep 16.


Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth.

Lang F, Stournaras C.

Hormones (Athens). 2013 Apr-Jun;12(2):160-71. Review.


Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors.

Sommer EM, Dry H, Cross D, Guichard S, Davies BR, Alessi DR.

Biochem J. 2013 Jun 15;452(3):499-508. doi: 10.1042/BJ20130342.


Serum- and glucocorticoid-regulated kinase 1 is required for nuclear export of the ribonucleoprotein of influenza A virus.

Alamares-Sapuay JG, Martinez-Gil L, Stertz S, Miller MS, Shaw ML, Palese P.

J Virol. 2013 May;87(10):6020-6. doi: 10.1128/JVI.01258-12. Epub 2013 Mar 13.


The cell survival kinase SGK1 and its targets FOXO3a and NDRG1 in aged human brain.

Sahin P, McCaig C, Jeevahan J, Murray JT, Hainsworth AH.

Neuropathol Appl Neurobiol. 2013 Oct;39(6):623-33. doi: 10.1111/nan.12023.


Investigation of the serum glucocorticoid kinase 1 gene in patients with transient tachypnea of the newborn.

Oztekin O, Akyol M, Kalay S, Tezel G, Akcakus M, Oygur N.

J Matern Fetal Neonatal Med. 2013 Jul;26(10):990-4. doi: 10.3109/14767058.2013.766709. Epub 2013 Feb 14.


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