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Items: 1 to 20 of 135

1.

Two novel heterozygous missense variations within the GLI2 gene in two unrelated Argentine patients.

Juanes M, Di Palma I, Ciaccio M, Marino R, Ramírez PC, Pérez Garrid N, Maceiras M, Lazzati JM, Rivarola MA, Belgorosky A.

Medicina (B Aires). 2016;76(4):213-8.

2.

Sonic Hedgehog Pathway Activation Is Associated With Resistance to Platinum-Based Chemotherapy in Advanced Non-Small-Cell Lung Carcinoma.

Giroux Leprieur E, Vieira T, Antoine M, Rozensztajn N, Rabbe N, Ruppert AM, Lavole A, Cadranel J, Wislez M.

Clin Lung Cancer. 2016 Jul;17(4):301-8. doi: 10.1016/j.cllc.2015.12.007. Epub 2015 Dec 17.

PMID:
26762562
3.

Up-Regulation of Glioma-Associated Oncogene Homolog 1 Expression by Serum Starvation Promotes Cell Survival in ER-Positive Breast Cancer Cells.

Xu J, Huang G, Zhang Z, Zhao J, Zhang M, Wang Y, Liu Z, Lu J.

Cell Physiol Biochem. 2015;36(5):1862-76.

4.

GLI2 mutations typically result in pituitary anomalies with or without postaxial polydactyly.

Bear KA, Solomon BD.

Am J Med Genet A. 2015 Oct;167A(10):2491-2. doi: 10.1002/ajmg.a.37160. Epub 2015 May 14. No abstract available.

PMID:
25974718
5.

GLI2 inhibition abrogates human leukemia stem cell dormancy.

Sadarangani A, Pineda G, Lennon KM, Chun HJ, Shih A, Schairer AE, Court AC, Goff DJ, Prashad SL, Geron I, Wall R, McPherson JD, Moore RA, Pu M, Bao L, Jackson-Fisher A, Munchhof M, VanArsdale T, Reya T, Morris SR, Minden MD, Messer K, Mikkola HK, Marra MA, Hudson TJ, Jamieson CH.

J Transl Med. 2015 Mar 21;13:98. doi: 10.1186/s12967-015-0453-9.

6.

Role of GLI2 in hypopituitarism phenotype.

Arnhold IJ, França MM, Carvalho LR, Mendonca BB, Jorge AA.

J Mol Endocrinol. 2015 Jun;54(3):R141-50. doi: 10.1530/JME-15-0009. Epub 2015 Apr 15. Review.

PMID:
25878059
7.

A familial GLI2 deletion (2q14.2) not associated with the holoprosencephaly syndrome phenotype.

Kordaß U, Schröder C, Elbracht M, Soellner L, Eggermann T.

Am J Med Genet A. 2015 May;167A(5):1121-4. doi: 10.1002/ajmg.a.36972. Epub 2015 Mar 28.

PMID:
25820550
8.

Gli2 silencing enhances TRAIL-induced apoptosis and reduces tumor growth in human hepatoma cells in vivo.

Zhang DW, Li HY, Lau WY, Cao LQ, Li Y, Jiang XF, Yang XW, Xue P.

Cancer Biol Ther. 2014;15(12):1667-76. doi: 10.4161/15384047.2014.972286.

9.

GLI2 is a novel therapeutic target for metastasis of osteosarcoma.

Nagao-Kitamoto H, Nagata M, Nagano S, Kitamoto S, Ishidou Y, Yamamoto T, Nakamura S, Tsuru A, Abematsu M, Fujimoto Y, Yokouchi M, Kitajima S, Yoshioka T, Maeda S, Yonezawa S, Komiya S, Setoguchi T.

Int J Cancer. 2015 Mar 15;136(6):1276-84. doi: 10.1002/ijc.29107. Epub 2014 Aug 8.

10.

Pathogenic mutations in GLI2 cause a specific phenotype that is distinct from holoprosencephaly.

Bear KA, Solomon BD, Antonini S, Arnhold IJ, França MM, Gerkes EH, Grange DK, Hadley DW, Jääskeläinen J, Paulo SS, Rump P, Stratakis CA, Thompson EM, Willis M, Winder TL, Jorge AA, Roessler E, Muenke M.

J Med Genet. 2014 Jun;51(6):413-8. doi: 10.1136/jmedgenet-2013-102249. Epub 2014 Apr 17.

PMID:
24744436
11.

GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis.

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh MT, Lu YJ, Philpott MP.

Cell Death Dis. 2014 Jan 30;5:e1028. doi: 10.1038/cddis.2013.535.

12.

Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer.

Huang L, Walter V, Hayes DN, Onaitis M.

Clin Cancer Res. 2014 Mar 15;20(6):1566-75. doi: 10.1158/1078-0432.CCR-13-2195. Epub 2014 Jan 14.

13.

Functional characterization of a heterozygous GLI2 missense mutation in patients with multiple pituitary hormone deficiency.

Flemming GM, Klammt J, Ambler G, Bao Y, Blum WF, Cowell C, Donaghue K, Howard N, Kumar A, Sanchez J, Stobbe H, Pfäffle RW.

J Clin Endocrinol Metab. 2013 Mar;98(3):E567-75. doi: 10.1210/jc.2012-3224. Epub 2013 Feb 13.

14.

Expression of glioma-associated oncogene 2 (Gli 2) is correlated with poor prognosis in patients with hepatocellular carcinoma undergoing hepatectomy.

Zhang D, Cao L, Li Y, Lu H, Yang X, Xue P.

World J Surg Oncol. 2013 Jan 29;11:25. doi: 10.1186/1477-7819-11-25.

15.

GLI2 mutations as a cause of hypopituitarism.

Cohen LE.

Pediatr Endocrinol Rev. 2012 Aug;9(4):706-9. Review.

PMID:
23304807
16.

MEK1-RSK2 contributes to Hedgehog signaling by stabilizing GLI2 transcription factor and inhibiting ubiquitination.

Liu Z, Li T, Reinhold MI, Naski MC.

Oncogene. 2014 Jan 2;33(1):65-73. doi: 10.1038/onc.2012.544. Epub 2012 Dec 3.

PMID:
23208494
17.

Relatively high frequency of non-synonymous GLI2 variants in patients with congenital hypopituitarism without holoprosencephaly.

França MM, Jorge AA, Carvalho LR, Costalonga EF, Otto AP, Correa FA, Mendonca BB, Arnhold IJ.

Clin Endocrinol (Oxf). 2013 Apr;78(4):551-7. doi: 10.1111/cen.12044.

PMID:
22967285
18.

Effect of TGF-β on Gli2 expression in HL60 and U937 cell lines.

Li Z, Pan D, Li Y.

Mol Med Rep. 2012 May;5(5):1245-50. doi: 10.3892/mmr.2012.820. Epub 2012 Mar 2.

PMID:
22395235
19.

Clinical findings in patients with GLI2 mutations--phenotypic variability.

Bertolacini CD, Ribeiro-Bicudo LA, Petrin A, Richieri-Costa A, Murray JC.

Clin Genet. 2012 Jan;81(1):70-5. doi: 10.1111/j.1399-0004.2010.01606.x. Epub 2011 Jan 19.

20.

Evidence for association of the GLI2 gene with tardive dyskinesia in patients with chronic schizophrenia.

Greenbaum L, Alkelai A, Rigbi A, Kohn Y, Lerer B.

Mov Disord. 2010 Dec 15;25(16):2809-17. doi: 10.1002/mds.23377.

PMID:
20939080

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