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Items: 1 to 20 of 21

1.

Hice1, a novel microtubule-associated protein required for maintenance of spindle integrity and chromosomal stability in human cells.

Wu G, Lin YT, Wei R, Chen Y, Shan Z, Lee WH.

Mol Cell Biol. 2008 Jun;28(11):3652-62. doi: 10.1128/MCB.01923-07. Epub 2008 Mar 24.

2.

Reconstitution of the augmin complex provides insights into its architecture and function.

Hsia KC, Wilson-Kubalek EM, Dottore A, Hao Q, Tsai KL, Forth S, Shimamoto Y, Milligan RA, Kapoor TM.

Nat Cell Biol. 2014 Sep;16(9):852-63. doi: 10.1038/ncb3030. Epub 2014 Aug 31.

3.

Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.

Tsai CY, Ngo B, Tapadia A, Hsu PH, Wu G, Lee WH.

J Biol Chem. 2011 Aug 26;286(34):30097-106. doi: 10.1074/jbc.M111.266767. Epub 2011 Jun 24.

4.

Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1.

Wu G, Wei R, Cheng E, Ngo B, Lee WH.

Mol Biol Cell. 2009 Nov;20(22):4686-95. doi: 10.1091/mbc.E08-11-1123. Epub 2009 Sep 23.

5.

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.

Lawo S, Bashkurov M, Mullin M, Ferreria MG, Kittler R, Habermann B, Tagliaferro A, Poser I, Hutchins JR, Hegemann B, Pinchev D, Buchholz F, Peters JM, Hyman AA, Gingras AC, Pelletier L.

Curr Biol. 2009 May 26;19(10):816-26. doi: 10.1016/j.cub.2009.04.033. Epub 2009 May 7.

6.

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle.

Goshima G, Mayer M, Zhang N, Stuurman N, Vale RD.

J Cell Biol. 2008 May 5;181(3):421-9. doi: 10.1083/jcb.200711053. Epub 2008 Apr 28.

7.

Immunomic analysis of human sarcoma.

Lee SY, Obata Y, Yoshida M, Stockert E, Williamson B, Jungbluth AA, Chen YT, Old LJ, Scanlan MJ.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2651-6. Epub 2003 Feb 24.

8.

The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.

Uehara R, Nozawa RS, Tomioka A, Petry S, Vale RD, Obuse C, Goshima G.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6998-7003. doi: 10.1073/pnas.0901587106. Epub 2009 Apr 14.

9.

Proximity interactions among centrosome components identify regulators of centriole duplication.

Firat-Karalar EN, Rauniyar N, Yates JR 3rd, Stearns T.

Curr Biol. 2014 Mar 17;24(6):664-70. doi: 10.1016/j.cub.2014.01.067. Epub 2014 Mar 6.

10.

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS.

EMBO J. 2011 Apr 20;30(8):1520-35. doi: 10.1038/emboj.2011.63. Epub 2011 Mar 11.

11.

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

Katsogiannou M, Andrieu C, Baylot V, Baudot A, Dusetti NJ, Gayet O, Finetti P, Garrido C, Birnbaum D, Bertucci F, Brun C, Rocchi P.

Mol Cell Proteomics. 2014 Dec;13(12):3585-601. doi: 10.1074/mcp.M114.041228. Epub 2014 Oct 2.

12.

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

Lambert JP, Tucholska M, Go C, Knight JD, Gingras AC.

J Proteomics. 2015 Apr 6;118:81-94. doi: 10.1016/j.jprot.2014.09.011. Epub 2014 Oct 2.

13.

Architecture of the human interactome defines protein communities and disease networks.

Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW.

Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17.

14.

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

Boldt K, van Reeuwijk J, Lu Q, Koutroumpas K, Nguyen TM, Texier Y, van Beersum SE, Horn N, Willer JR, Mans DA, Dougherty G, Lamers IJ, Coene KL, Arts HH, Betts MJ, Beyer T, Bolat E, Gloeckner CJ, Haidari K, Hetterschijt L, Iaconis D, Jenkins D, Klose F, Knapp B, Latour B, Letteboer SJ, Marcelis CL, Mitic D, Morleo M, Oud MM, Riemersma M, Rix S, Terhal PA, Toedt G, van Dam TJ, de Vrieze E, Wissinger Y, Wu KM, Apic G, Beales PL, Blacque OE, Gibson TJ, Huynen MA, Katsanis N, Kremer H, Omran H, van Wijk E, Wolfrum U, Kepes F, Davis EE, Franco B, Giles RH, Ueffing M, Russell RB, Roepman R; UK10K Rare Diseases Group.

Nat Commun. 2016 May 13;7:11491. doi: 10.1038/ncomms11491.

15.

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

Kırlı K, Karaca S, Dehne HJ, Samwer M, Pan KT, Lenz C, Urlaub H, Görlich D.

Elife. 2015 Dec 17;4. pii: e11466. doi: 10.7554/eLife.11466.

16.

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.

Gupta GD, Coyaud É, Gonçalves J, Mojarad BA, Liu Y, Wu Q, Gheiratmand L, Comartin D, Tkach JM, Cheung SW, Bashkurov M, Hasegan M, Knight JD, Lin ZY, Schueler M, Hildebrandt F, Moffat J, Gingras AC, Raught B, Pelletier L.

Cell. 2015 Dec 3;163(6):1484-99. doi: 10.1016/j.cell.2015.10.065.

17.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M.

Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.

18.

The BioPlex Network: A Systematic Exploration of the Human Interactome.

Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP.

Cell. 2015 Jul 16;162(2):425-40. doi: 10.1016/j.cell.2015.06.043.

19.

Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein.

Oláh J, Vincze O, Virók D, Simon D, Bozsó Z, Tõkési N, Horváth I, Hlavanda E, Kovács J, Magyar A, Szũcs M, Orosz F, Penke B, Ovádi J.

J Biol Chem. 2011 Sep 30;286(39):34088-100. doi: 10.1074/jbc.M111.243907. Epub 2011 Aug 8.

20.

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM.

Science. 2010 Apr 30;328(5978):593-9. doi: 10.1126/science.1181348. Epub 2010 Apr 1.

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