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Items: 1 to 20 of 35

1.

A role for mammalian Ubc6 homologues in ER-associated protein degradation.

Lenk U, Yu H, Walter J, Gelman MS, Hartmann E, Kopito RR, Sommer T.

J Cell Sci. 2002 Jul 15;115(Pt 14):3007-14.

2.

Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2.

Kim BW, Zavacki AM, Curcio-Morelli C, Dentice M, Harney JW, Larsen PR, Bianco AC.

Mol Endocrinol. 2003 Dec;17(12):2603-12. Epub 2003 Aug 21.

PMID:
12933904
3.

Identification of a family of noncanonical ubiquitin-conjugating enzymes structurally related to yeast UBC6.

Lester D, Farquharson C, Russell G, Houston B.

Biochem Biophys Res Commun. 2000 Mar 16;269(2):474-80.

PMID:
10708578
4.

Analysis of CFTR folding and degradation in transiently transfected cells.

Grove DE, Rosser MF, Watkins RL, Cyr DM.

Methods Mol Biol. 2011;741:219-32. doi: 10.1007/978-1-61779-117-8_15.

5.

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.

Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R.

Cell. 2001 Jun 29;105(7):891-902.

6.
7.

TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination.

Wu CJ, Conze DB, Li X, Ying SX, Hanover JA, Ashwell JD.

EMBO J. 2005 May 18;24(10):1886-98. Epub 2005 Apr 28.

8.

Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production.

Menon MB, Tiedje C, Lafera J, Ronkina N, Konen T, Kotlyarov A, Gaestel M.

Biochem J. 2013 Dec 1;456(2):163-72. doi: 10.1042/BJ20130755. Erratum in: Biochem J. 2014 Jan 1;457(1):229.

PMID:
24020373
9.

HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation.

Burr ML, Cano F, Svobodova S, Boyle LH, Boname JM, Lehner PJ.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2034-9. doi: 10.1073/pnas.1016229108. Epub 2011 Jan 18.

10.

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level.

Pattaro C, De Grandi A, Vitart V, Hayward C, Franke A, Aulchenko YS, Johansson A, Wild SH, Melville SA, Isaacs A, Polasek O, Ellinghaus D, Kolcic I, Nöthlings U, Zgaga L, Zemunik T, Gnewuch C, Schreiber S, Campbell S, Hastie N, Boban M, Meitinger T, Oostra BA, Riegler P, Minelli C, Wright AF, Campbell H, van Duijn CM, Gyllensten U, Wilson JF, Krawczak M, Rudan I, Pramstaller PP; EUROSPAN consortium..

BMC Med Genet. 2010 Mar 11;11:41. doi: 10.1186/1471-2350-11-41.

11.

STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.

Sato T, Sako Y, Sho M, Momohara M, Suico MA, Shuto T, Nishitoh H, Okiyoneda T, Kokame K, Kaneko M, Taura M, Miyata M, Chosa K, Koga T, Morino-Koga S, Wada I, Kai H.

Mol Cell. 2012 Jul 13;47(1):99-110. doi: 10.1016/j.molcel.2012.04.015. Epub 2012 May 17.

12.

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.

Younger JM, Chen L, Ren HY, Rosser MF, Turnbull EL, Fan CY, Patterson C, Cyr DM.

Cell. 2006 Aug 11;126(3):571-82.

13.

RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR).

El Khouri E, Le Pavec G, Toledano MB, Delaunay-Moisan A.

J Biol Chem. 2013 Oct 25;288(43):31177-91. doi: 10.1074/jbc.M113.470500. Epub 2013 Sep 9.

14.

The transmembrane segment of a tail-anchored protein determines its degradative fate through dislocation from the endoplasmic reticulum.

Claessen JH, Mueller B, Spooner E, Pivorunas VL, Ploegh HL.

J Biol Chem. 2010 Jul 2;285(27):20732-9. doi: 10.1074/jbc.M110.120766. Epub 2010 Apr 30.

15.

A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling.

Fallon L, Bélanger CM, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, Voortman J, Haber M, Rouleau G, Thorarinsdottir T, Brice A, van Bergen En Henegouwen PM, Fon EA.

Nat Cell Biol. 2006 Aug;8(8):834-42. Epub 2006 Jul 23.

PMID:
16862145
16.

BAG5 inhibits parkin and enhances dopaminergic neuron degeneration.

Kalia SK, Lee S, Smith PD, Liu L, Crocker SJ, Thorarinsdottir TE, Glover JR, Fon EA, Park DS, Lozano AM.

Neuron. 2004 Dec 16;44(6):931-45.

17.

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.

Mueller B, Klemm EJ, Spooner E, Claessen JH, Ploegh HL.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12325-30. doi: 10.1073/pnas.0805371105. Epub 2008 Aug 18.

18.

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.

Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R.

Mol Cell. 2002 Jul;10(1):55-67.

19.

Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control.

Klemm EJ, Spooner E, Ploegh HL.

J Biol Chem. 2011 Oct 28;286(43):37602-14. doi: 10.1074/jbc.M111.284794. Epub 2011 Aug 20.

20.

Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK).

Zhong Y, Shen H, Wang Y, Yang Y, Yang P, Fang S.

Biochem Biophys Res Commun. 2015 Mar 6;458(2):424-8. doi: 10.1016/j.bbrc.2015.01.133. Epub 2015 Feb 7.

PMID:
25660456

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