Sort by
Items per page

Send to

Choose Destination

Links from Gene

Items: 1 to 20 of 208


Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1.

Dufour C, Claudel A, Joubarne N, Merindol N, Maisonnet T, Masroori N, Plourde MB, Berthoux L.

PLoS One. 2018 Jan 26;13(1):e0191709. doi: 10.1371/journal.pone.0191709. eCollection 2018.


Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis.

Nozuma S, Matsuura E, Kodama D, Tashiro Y, Matsuzaki T, Kubota R, Izumo S, Takashima H.

Retrovirology. 2017 Apr 19;14(1):26. doi: 10.1186/s12977-017-0350-9.


Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets.

Ribeiro CM, Sarrami-Forooshani R, Setiawan LC, Zijlstra-Willems EM, van Hamme JL, Tigchelaar W, van der Wel NN, Kootstra NA, Gringhuis SI, Geijtenbeek TB.

Nature. 2016 Dec 15;540(7633):448-452. doi: 10.1038/nature20567. Epub 2016 Dec 7.


TRIM5 gene polymorphisms in HIV-1-infected patients and healthy controls from Northeastern Brazil.

Celerino da Silva R, Coelho AV, Arraes LC, Brandão LA, Crovella S, Guimarães RL.

Immunol Res. 2016 Dec;64(5-6):1237-1242.


TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction.

Imam S, Talley S, Nelson RS, Dharan A, O'Connor C, Hope TJ, Campbell EM.

J Virol. 2016 Jan 13;90(7):3400-10. doi: 10.1128/JVI.03033-15.


TRIM5α H43Y Polymorphism and Susceptibility to HIV-1 Infection: A Meta-Analysis.

Deng J, Chen Y, Ding D, Lu P, Yang X, Song Z, Zhu H.

AIDS Res Hum Retroviruses. 2015 Dec;31(12):1213-8. doi: 10.1089/aid.2015.0067. Epub 2015 Sep 23.


Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene.

Jung U, Urak K, Veillette M, Nepveu-Traversy MÉ, Pham QT, Hamel S, Rossi JJ, Berthoux L.

Hum Gene Ther. 2015 Oct;26(10):664-79. doi: 10.1089/hum.2015.059. Epub 2015 Aug 6.


TRIMe7-CypA, an alternative splicing isoform of TRIMCyp in rhesus macaque, negatively modulates TRIM5α activity.

Na L, Tang YD, Liu JD, Yu CQ, Sun LK, Lin YZ, Wang XF, Wang X, Zhou JH.

Biochem Biophys Res Commun. 2014 Apr 4;446(2):470-4. doi: 10.1016/j.bbrc.2014.02.132. Epub 2014 Mar 12.


TRIM5α variations influence transduction efficiency with lentiviral vectors in both human and rhesus CD34(+) cells in vitro and in vivo.

Evans ME, Kumkhaek C, Hsieh MM, Donahue RE, Tisdale JF, Uchida N.

Mol Ther. 2014 Feb;22(2):348-358. doi: 10.1038/mt.2013.256. Epub 2013 Oct 23.


Retrovirus restriction by TRIM5 proteins requires recognition of only a small fraction of viral capsid subunits.

Shi J, Friedman DB, Aiken C.

J Virol. 2013 Aug;87(16):9271-8. doi: 10.1128/JVI.00713-13. Epub 2013 Jun 19.


Viral attachment induces rapid recruitment of an innate immune sensor (TRIM5α) to the plasma membrane.

Ohmine S, Singh RD, Marks DL, Meyer MA, Pagano RE, Ikeda Y.

J Innate Immun. 2013;5(4):414-24. doi: 10.1159/000346963. Epub 2013 Mar 21.


Fates of retroviral core components during unrestricted and TRIM5-restricted infection.

Kutluay SB, Perez-Caballero D, Bieniasz PD.

PLoS Pathog. 2013 Mar;9(3):e1003214. doi: 10.1371/journal.ppat.1003214. Epub 2013 Mar 7.


TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling.

Grütter MG, Luban J.

Curr Opin Virol. 2012 Apr;2(2):142-50. doi: 10.1016/j.coviro.2012.02.003. Epub 2012 Mar 5. Review.


Modulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.

Battivelli E, Migraine J, Lecossier D, Matsuoka S, Perez-Bercoff D, Saragosti S, Clavel F, Hance AJ.

J Virol. 2011 Aug;85(15):7828-35. doi: 10.1128/JVI.00648-11. Epub 2011 Jun 1.


Novel escape mutants suggest an extensive TRIM5α binding site spanning the entire outer surface of the murine leukemia virus capsid protein.

Ohkura S, Goldstone DC, Yap MW, Holden-Dye K, Taylor IA, Stoye JP.

PLoS Pathog. 2011 Mar;7(3):e1002011. doi: 10.1371/journal.ppat.1002011. Epub 2011 Mar 31.


Hexagonal assembly of a restricting TRIM5alpha protein.

Ganser-Pornillos BK, Chandrasekaran V, Pornillos O, Sodroski JG, Sundquist WI, Yeager M.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):534-9. doi: 10.1073/pnas.1013426108. Epub 2010 Dec 27.


An HIV-1 resistance polymorphism in TRIM5α gene among Chinese intravenous drug users.

Liu FL, Qiu YQ, Li H, Kuang YQ, Tang X, Cao G, Tang NL, Zheng YT.

J Acquir Immune Defic Syndr. 2011 Apr;56(4):306-11. doi: 10.1097/QAI.0b013e318205a59b.


A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort.

Price H, Lacap P, Tuff J, Wachihi C, Kimani J, Ball TB, Luo M, Plummer FA.

AIDS. 2010 Jul 31;24(12):1813-21. doi: 10.1097/QAD.0b013e32833b5256.


Inhibitory effect of human TRIM5alpha on HIV-1 production.

Zhang X, Kondo M, Chen J, Miyoshi H, Suzuki H, Ohashi T, Shida H.

Microbes Infect. 2010 Sep;12(10):768-77. doi: 10.1016/j.micinf.2010.05.004. Epub 2010 May 21.


Impact of novel TRIM5alpha variants, Gly110Arg and G176del, on the anti-HIV-1 activity and the susceptibility to HIV-1 infection.

Nakajima T, Nakayama EE, Kaur G, Terunuma H, Mimaya JI, Ohtani H, Mehra N, Shioda T, Kimura A.

AIDS. 2009 Oct 23;23(16):2091-100. doi: 10.1097/QAD.0b013e328331567a.


Supplemental Content

Support Center