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Items: 1 to 20 of 169


Hyperforin/HP-β-Cyclodextrin Enhances Mechanosensitive Ca2+ Signaling in HaCaT Keratinocytes and in Atopic Skin Ex Vivo Which Accelerates Wound Healing.

Takada H, Yonekawa J, Matsumoto M, Furuya K, Sokabe M.

Biomed Res Int. 2017;2017:8701801. doi: 10.1155/2017/8701801. Epub 2017 Jan 22.


Inhibition of TRPC6 reduces non-small cell lung cancer cell proliferation and invasion.

Yang LL, Liu BC, Lu XY, Yan Y, Zhai YJ, Bao Q, Doetsch PW, Deng X, Thai TL, Alli AA, Eaton DC, Shen BZ, Ma HP.

Oncotarget. 2017 Jan 17;8(3):5123-5134. doi: 10.18632/oncotarget.14034.


Significant contribution of TRPC6 channel-mediated Ca2+ influx to the pathogenesis of Crohn's disease fibrotic stenosis.

Kurahara LH, Hiraishi K, Sumiyoshi M, Doi M, Hu Y, Aoyagi K, Jian Y, Inoue R.

J Smooth Muscle Res. 2016;52(0):78-92. Review.


Regulation of Multi-drug Resistance in hepatocellular carcinoma cells is TRPC6/Calcium Dependent.

Wen L, Liang C, Chen E, Chen W, Liang F, Zhi X, Wei T, Xue F, Li G, Yang Q, Gong W, Feng X, Bai X, Liang T.

Sci Rep. 2016 Mar 24;6:23269. doi: 10.1038/srep23269.


Canonical Transient Receptor Potential 6 Channel: A New Target of Reactive Oxygen Species in Renal Physiology and Pathology.

Ma R, Chaudhari S, Li W.

Antioxid Redox Signal. 2016 Nov 1;25(13):732-748. Epub 2016 Mar 18. Review.


TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.

Riehle M, Büscher AK, Gohlke BO, Kaßmann M, Kolatsi-Joannou M, Bräsen JH, Nagel M, Becker JU, Winyard P, Hoyer PF, Preissner R, Krautwurst D, Gollasch M, Weber S, Harteneck C.

J Am Soc Nephrol. 2016 Sep;27(9):2771-83. doi: 10.1681/ASN.2015030318. Epub 2016 Feb 18.


TRPC6 gene variants and neuropsychiatric lupus.

Ramirez GA, Lanzani C, Bozzolo EP, Citterio L, Zagato L, Casamassima N, Canti V, Sabbadini MG, Rovere-Querini P, Manunta P, Manfredi AA.

J Neuroimmunol. 2015 Nov 15;288:21-4. doi: 10.1016/j.jneuroim.2015.08.015. Epub 2015 Aug 28.


Genetic Interactions Between TRPC6 and NPHS1 Variants Affect Posttransplant Risk of Recurrent Focal Segmental Glomerulosclerosis.

Sun ZJ, Ng KH, Liao P, Zhang Y, Ng JL, Liu ID, Tan PH, Chong SS, Chan YH, Liu J, Davila S, Heng CK, Jordan SC, Soong TW, Yap HK.

Am J Transplant. 2015 Dec;15(12):3229-38. doi: 10.1111/ajt.13378. Epub 2015 Jul 3.


In silico analysis of functional nsSNPs in human TRPC6 gene associated with steroid resistant nephrotic syndrome.

Joshi BB, Koringa PG, Mistry KN, Patel AK, Gang S, Joshi CG.

Gene. 2015 Nov 1;572(1):8-16. doi: 10.1016/j.gene.2015.06.069. Epub 2015 Jun 27.


Acute ethanol induces apoptosis by stimulating TRPC6 via elevation of superoxide in oxygenated podocytes.

Lu XY, Liu BC, Wang LH, Yang LL, Bao Q, Zhai YJ, Alli AA, Thai TL, Eaton DC, Wang WZ, Ma HP.

Biochim Biophys Acta. 2015 May;1853(5):965-74. doi: 10.1016/j.bbamcr.2015.01.007. Epub 2015 Jan 17.


Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons.

Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR.

Mol Psychiatry. 2015 Nov;20(11):1350-65. doi: 10.1038/mp.2014.141. Epub 2014 Nov 11.


TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy.

Hofstra JM, Coenen MJ, Schijvenaars MM, Berden JH, van der Vlag J, Hoefsloot LH, Knoers NV, Wetzels JF, Nijenhuis T.

PLoS One. 2014 Jul 14;9(7):e102065. doi: 10.1371/journal.pone.0102065. eCollection 2014.


A mutation in TRPC6 channels abolishes their activation by hypoosmotic stretch but does not affect activation by diacylglycerol or G protein signaling cascades.

Wilson C, Dryer SE.

Am J Physiol Renal Physiol. 2014 May 1;306(9):F1018-25. doi: 10.1152/ajprenal.00662.2013. Epub 2014 Mar 5.


Effects of TRPC6 on invasibility of low-differentiated prostate cancer cells.

Wang D, Li X, Liu J, Li J, Li LJ, Qiu MX.

Asian Pac J Trop Med. 2014 Jan;7(1):44-7. doi: 10.1016/S1995-7645(13)60190-X.


254C>G: a TRPC6 promoter variation associated with enhanced transcription and steroid-resistant nephrotic syndrome in Chinese children.

Kuang XY, Huang WY, Xu H, Shi Y, Zhang XL, Niu XL, Wu Y, Mei CZ, Zha XL, Zhao ZH, Zhang ZG.

Pediatr Res. 2013 Nov;74(5):511-6. doi: 10.1038/pr.2013.144. Epub 2013 Sep 2.


Critical role of TRPC6 channels in the development of human renal cell carcinoma.

Song J, Wang Y, Li X, Shen Y, Yin M, Guo Y, Diao L, Liu Y, Yue D.

Mol Biol Rep. 2013 Aug;40(8):5115-22. doi: 10.1007/s11033-013-2613-4. Epub 2013 May 23.


High expression of transient potential receptor C6 correlated with poor prognosis in patients with esophageal squamous cell carcinoma.

Zhang SS, Wen J, Yang F, Cai XL, Yang H, Luo KJ, Liu QW, Hu RG, Xie X, Huang QY, Chen JY, Fu JH, Hu Y.

Med Oncol. 2013;30(3):607. doi: 10.1007/s12032-013-0607-7. Epub 2013 May 18.


A novel TRPC6 mutation in a family with podocytopathy and clinical variability.

Mottl AK, Lu M, Fine CA, Weck KE.

BMC Nephrol. 2013 May 10;14:104. doi: 10.1186/1471-2369-14-104.


Increased expression of the transient receptor potential cation channel 6 gene in patients with primary open-angle glaucoma.

Chen S, Fan Q, Gao X, Wang X, Huang R, Laties AM, Zhang X.

Clin Exp Ophthalmol. 2013 Nov;41(8):753-60. doi: 10.1111/ceo.12111. Epub 2013 Apr 25.


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