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Items: 1 to 20 of 143


Is RNASEL:p.Glu265* a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

Nguyen-Dumont T, Teo ZL, Hammet F, Roberge A, Mahmoodi M, Tsimiklis H, Park DJ, Pope BJ, Lonie A, Kapuscinski MK, Mahmood K; ABCFR, Goldgar DE, Giles GG, Winship I, Hopper JL, Southey MC.

BMC Cancer. 2018 Feb 8;18(1):165. doi: 10.1186/s12885-018-4028-z.


Rapid RNase L-driven arrest of protein synthesis in the dsRNA response without degradation of translation machinery.

Donovan J, Rath S, Kolet-Mandrikov D, Korennykh A.

RNA. 2017 Nov;23(11):1660-1671. doi: 10.1261/rna.062000.117. Epub 2017 Aug 14.


Human serum RNase-L level is inversely associated with metabolic syndrome and age.

Wang YT, Tseng PH, Chen CL, Han DS, Chi YC, Tseng FY, Yang WS.

Cardiovasc Diabetol. 2017 Apr 11;16(1):46. doi: 10.1186/s12933-017-0522-x.


RNase L Suppresses Androgen Receptor Signaling, Cell Migration and Matrix Metalloproteinase Activity in Prostate Cancer Cells.

Dayal S, Zhou J, Manivannan P, Siddiqui MA, Ahmad OF, Clark M, Awadia S, Garcia-Mata R, Shemshedini L, Malathi K.

Int J Mol Sci. 2017 Mar 1;18(3). pii: E529. doi: 10.3390/ijms18030529.


The Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate Response.

Ezelle HJ, Malathi K, Hassel BA.

Int J Mol Sci. 2016 Jan 8;17(1). pii: E74. doi: 10.3390/ijms17010074. Review.


Human RNase L tunes gene expression by selectively destabilizing the microRNA-regulated transcriptome.

Rath S, Donovan J, Whitney G, Chitrakar A, Wang W, Korennykh A.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15916-21. doi: 10.1073/pnas.1513034112. Epub 2015 Dec 14.


Functional and Structural Consequences of Damaging Single Nucleotide Polymorphisms in Human Prostate Cancer Predisposition Gene RNASEL.

Datta A, Mazumder MH, Chowdhury AS, Hasan MA.

Biomed Res Int. 2015;2015:271458. doi: 10.1155/2015/271458. Epub 2015 Jul 8.


RNase L attenuates mitogen-stimulated gene expression via transcriptional and post-transcriptional mechanisms to limit the proliferative response.

Brennan-Laun SE, Li XL, Ezelle HJ, Venkataraman T, Blackshear PJ, Wilson GM, Hassel BA.

J Biol Chem. 2014 Nov 28;289(48):33629-43. doi: 10.1074/jbc.M114.589556. Epub 2014 Oct 9.


Association of RNASEL and 8q24 variants with the presence and aggressiveness of hereditary and sporadic prostate cancer in a Hispanic population.

San Francisco IF, Rojas PA, Torres-Estay V, Smalley S, Cerda-Infante J, Montecinos VP, Hurtado C, Godoy AS.

J Cell Mol Med. 2014 Jan;18(1):125-33. doi: 10.1111/jcmm.12171. Epub 2013 Nov 14.


A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancer.

Schoenfeld JD, Margalit DN, Kasperzyk JL, Shui IM, Rider JR, Epstein MM, Meisner A, Kenfield SA, Martin NE, Nguyen PL, Kantoff PW, Giovannucci EL, Stampfer MJ, Mucci LA.

Clin Cancer Res. 2013 Mar 15;19(6):1612-9. doi: 10.1158/1078-0432.CCR-12-2718. Epub 2013 Feb 4.


Innate immune messenger 2-5A tethers human RNase L into active high-order complexes.

Han Y, Whitney G, Donovan J, Korennykh A.

Cell Rep. 2012 Oct 25;2(4):902-13. doi: 10.1016/j.celrep.2012.09.004. Epub 2012 Oct 19.


Structural changes of human RNase L upon homodimerization investigated by Raman spectroscopy.

Kříž M, Snášel J, Kopecký V Jr, Páv O, Rosenberg I, Stěpánek J.

Biochim Biophys Acta. 2012 Sep;1824(9):1039-44. doi: 10.1016/j.bbapap.2012.06.002. Epub 2012 Jun 9.


Positive selection on the gene RNASEL: correlation between patterns of evolution and function.

Jin W, Wu DD, Zhang X, Irwin DM, Zhang YP.

Mol Biol Evol. 2012 Oct;29(10):3161-8. Epub 2012 Apr 17.


[RNASEL study of genetics of prostate cancer and its relation to clinical staging].

Alvarez-Cubero MJ, Saiz M, Martínez-González LJ, Alvarez JC, Lorente JA, Cozar JM.

Actas Urol Esp. 2012 May;36(5):306-11. doi: 10.1016/j.acuro.2011.12.002. Epub 2012 Mar 30. Spanish.


Predictive value in the analysis of RNASEL genotypes in relation to prostate cancer.

Alvarez-Cubero MJ, Entrala C, Fernandez-Rosado F, Martinez-Gonzalez LJ, Alvarez JC, Suarez A, Lorente JA, Cozar JM.

Prostate Cancer Prostatic Dis. 2012 Jun;15(2):144-9. doi: 10.1038/pcan.2011.56. Epub 2011 Nov 15.


Lopinavir up-regulates expression of the antiviral protein ribonuclease L in human papillomavirus-positive cervical carcinoma cells.

Batman G, Oliver AW, Zehbe I, Richard C, Hampson L, Hampson IN.

Antivir Ther. 2011;16(4):515-25. doi: 10.3851/IMP1786.


RNASEL Asp541Glu and Arg462Gln polymorphisms in prostate cancer risk: evidences from a meta-analysis.

Wei B, Xu Z, Ruan J, Zhu M, Jin K, Zhou D, Yan Z, Xuan F, Zhou H, Huang X, Zhang J, Lu P, Shao J.

Mol Biol Rep. 2012 Mar;39(3):2347-53. doi: 10.1007/s11033-011-0985-x. Epub 2011 Jun 9.


Genetic variation in RNASEL and risk for prostate cancer in a population-based case-control study.

Fesinmeyer MD, Kwon EM, Fu R, Ostrander EA, Stanford JL.

Prostate. 2011 Oct 1;71(14):1538-47. doi: 10.1002/pros.21370. Epub 2011 Feb 25.

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