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Items: 1 to 20 of 28

1.

Human Cytochrome P450 2W1 Is Not Expressed in Adrenal Cortex and Is Only Rarely Expressed in Adrenocortical Carcinomas.

Nolé P, Duijndam B, Stenman A, Juhlin CC, Kozyra M, Larsson C, Ingelman-Sundberg M, Johansson I.

PLoS One. 2016 Sep 6;11(9):e0162379. doi: 10.1371/journal.pone.0162379. eCollection 2016.

2.

Identification of Genetic Polymorphisms of CYP2W1 in the Three Main Chinese Ethnicities: Han, Tibetan, and Uighur.

Li Y, Kang X, Yang G, Dai P, Chen C, Wang H.

Drug Metab Dispos. 2016 Sep;44(9):1510-5. doi: 10.1124/dmd.115.069153. Epub 2016 Jun 15. Erratum in: Drug Metab Dispos. 2017 Oct;45(10 ):1113.

3.

The CYP2W1 enzyme: regulation, properties and activation of prodrugs.

Guo J, Johansson I, Mkrtchian S, Ingelman-Sundberg M.

Drug Metab Rev. 2016 Aug;48(3):369-78. doi: 10.1080/03602532.2016.1188939. Epub 2016 Jun 3. Review.

PMID:
27257736
4.

Membrane topology and search for potential redox partners of colon cancer-specific cytochrome P450 2W1.

Guo J, Thiess S, Johansson I, Mkrtchian S, Ingelman-Sundberg M.

FEBS Lett. 2016 Feb;590(3):330-9. doi: 10.1002/1873-3468.12063. Epub 2016 Feb 2.

5.

Novel single nucleotide polymorphisms (SNPs) of CYP2W1 gene in Chinese Uygur and Han populations.

Qi GZ, Wang X, Miao XJ, Yin SJ, Ren H, Lou YQ, Zhang GL.

Drug Metab Pharmacokinet. 2015 Dec;30(6):449-52. doi: 10.1016/j.dmpk.2015.11.003. Epub 2015 Nov 24.

PMID:
26683388
6.

CYP2W1 is highly expressed in adrenal glands and is positively associated with the response to mitotane in adrenocortical carcinoma.

Ronchi CL, Sbiera S, Volante M, Steinhauer S, Scott-Wild V, Altieri B, Kroiss M, Bala M, Papotti M, Deutschbein T, Terzolo M, Fassnacht M, Allolio B.

PLoS One. 2014 Aug 21;9(8):e105855. doi: 10.1371/journal.pone.0105855. eCollection 2014.

7.

Prognostic value of CYP2W1 expression in patients with human hepatocellular carcinoma.

Zhang K, Jiang L, He R, Li BL, Jia Z, Huang RH, Mu Y.

Tumour Biol. 2014 Aug;35(8):7669-73. doi: 10.1007/s13277-014-2023-9. Epub 2014 May 7.

PMID:
24801906
8.

The expression of CYP2W1 in colorectal primary tumors, corresponding lymph node metastases and liver metastases.

Stenstedt K, Hallstrom M, Lédel F, Ragnhammar P, Ingelman-Sundberg M, Johansson I, Edler D.

Acta Oncol. 2014 Jul;53(7):885-91. doi: 10.3109/0284186X.2014.887224. Epub 2014 Mar 13.

PMID:
24625228
9.

CYP2W1 polymorphism: functional aspects and relation to risk for colorectal cancer.

Stenstedt K, Travica S, Guo J, Barragan I, Pors K, Patterson L, Edler D, Mkrtchian S, Johansson I, Ingelman-Sundberg M.

Pharmacogenomics. 2013 Oct;14(13):1615-22. doi: 10.2217/pgs.13.136.

PMID:
24088132
10.

The expression of CYP2W1: a prognostic marker in colon cancer.

Stenstedt K, Hallstrom M, Johansson I, Ingelman-Sundberg M, Ragnhammar P, Edler D.

Anticancer Res. 2012 Sep;32(9):3869-74.

PMID:
22993331
11.

CYP2W1, CYP4F11 and CYP8A1 polymorphisms and interaction of CYP2W1 genotypes with risk factors in Mexican women with breast cancer.

Cárdenas-Rodríguez N, Lara-Padilla E, Bandala C, López-Cruz J, Uscanga-Carmona C, Lucio-Monter PF, Floriano-Sánchez E.

Asian Pac J Cancer Prev. 2012;13(3):837-46.

12.

Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipids.

Xiao Y, Guengerich FP.

J Lipid Res. 2012 Aug;53(8):1610-7. doi: 10.1194/jlr.M027185. Epub 2012 May 16. Erratum in: J Lipid Res. 2013 May;54(5):1521.

13.

CYP2W1 variant alleles in Caucasians and association of the CYP2W1 G541A (Ala181Thr) polymorphism with increased colorectal cancer risk.

Gervasini G, de Murillo SG, Ladero JM, Agúndez JA.

Pharmacogenomics. 2010 Jul;11(7):919-25. doi: 10.2217/pgs.10.66.

PMID:
20602611
14.

Genetic polymorphisms and haplotype structures of the human CYP2W1 gene in a Japanese population.

Hanzawa Y, Sasaki T, Mizugaki M, Ishikawa M, Hiratsuka M.

Drug Metab Dispos. 2008 Feb;36(2):349-52. Epub 2007 Nov 12.

15.

Expression of CYP2W1 in colon tumors: regulation by gene methylation.

Gomez A, Karlgren M, Edler D, Bernal ML, Mkrtchian S, Ingelman-Sundberg M.

Pharmacogenomics. 2007 Oct;8(10):1315-25.

PMID:
17979506
16.

Enzymatic properties of human CYP2W1 expressed in Escherichia coli.

Yoshioka H, Kasai N, Ikushiro S, Shinkyo R, Kamakura M, Ohta M, Inouye K, Sakaki T.

Biochem Biophys Res Commun. 2006 Jun 23;345(1):169-74. Epub 2006 Apr 27.

PMID:
16677611
17.

Developmental regulation and induction of cytochrome P450 2W1, an enzyme expressed in colon tumors.

Choong E, Guo J, Persson A, Virding S, Johansson I, Mkrtchian S, Ingelman-Sundberg M.

PLoS One. 2015 Apr 6;10(4):e0122820. doi: 10.1371/journal.pone.0122820. eCollection 2015.

18.

Colorectal cancer-specific cytochrome P450 2W1: intracellular localization, glycosylation, and catalytic activity.

Gomez A, Nekvindova J, Travica S, Lee MY, Johansson I, Edler D, Mkrtchian S, Ingelman-Sundberg M.

Mol Pharmacol. 2010 Dec;78(6):1004-11. doi: 10.1124/mol.110.067652. Epub 2010 Aug 30.

19.
20.

Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

Karlgren M, Gomez A, Stark K, Svärd J, Rodriguez-Antona C, Oliw E, Bernal ML, Ramón y Cajal S, Johansson I, Ingelman-Sundberg M.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):451-8. Epub 2006 Jan 11.

PMID:
16426568

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