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Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming.

Ma L, Cheng Q.

Biochem Biophys Res Commun. 2018 Apr 15;498(4):912-917. doi: 10.1016/j.bbrc.2018.03.079. Epub 2018 Mar 14.


1p36.22 region containing PGD gene is frequently gained in human cervical cancer.

Lee M, Nam ES, Jung SH, Kim SY, Lee SJ, Yoon JH, Lee NW, Jeon S, Choi JS, Cho CH, Moon Y, Chung YJ, Kwon Y.

J Obstet Gynaecol Res. 2014 Feb;40(2):545-53. doi: 10.1111/jog.12193. Epub 2013 Oct 11.


Identification of a cDNA encoding 6-phosphogluconate dehydrogenase from a human heart cDNA library.

Tsui SK, Chan JY, Waye MM, Fung KP, Lee CY.

Biochem Genet. 1996 Oct;34(9-10):367-73.


Report of the Committee on the Genetic Constitution of Chromosomes 1 and 2.

Povey S, Morton NE, Sherman SL.

Cytogenet Cell Genet. 1985;40(1-4):67-106. No abstract available.


PGD phenotyping in bloodstains, organ tissues, dental pulps and hair roots by isoelectric focusing.

Komatsu N, Kido A, Kimura Y, Oya M.

Forensic Sci Int. 1990 Dec;48(2):185-94.


6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met.

Chan B, VanderLaan PA, Sukhatme VP.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):247-51. doi: 10.1016/j.bbrc.2013.08.048. Epub 2013 Aug 22.


Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.

Sukhatme VP, Chan B.

FEBS Lett. 2012 Jul 30;586(16):2389-95. doi: 10.1016/j.febslet.2012.05.052. Epub 2012 Jun 4.


Coupling of 6-phosphogluconate dehydrogenase with NADPH oxidase in neutrophils: Nox2 activity regulation by NADPH availability.

Baillet A, Xu R, Grichine A, Berthier S, Morel F, Paclet MH.

FASEB J. 2011 Jul;25(7):2333-43. doi: 10.1096/fj.10-173807. Epub 2011 Mar 28.


MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Kim AH, Reimers M, Maher B, Williamson V, McMichael O, McClay JL, van den Oord EJ, Riley BP, Kendler KS, Vladimirov VI.

Schizophr Res. 2010 Dec;124(1-3):183-91. doi: 10.1016/j.schres.2010.07.002. Epub 2010 Aug 2.


6-Phosphogluconate dehydrogenase: the mechanism of action investigated by a comparison of the enzyme from different species.

Rippa M, Giovannini PP, Barrett MP, Dallocchio F, Hanau S.

Biochim Biophys Acta. 1998 Dec 8;1429(1):83-92.


Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers.

Zhang H, Zhai Y, Hu Z, Wu C, Qian J, Jia W, Ma F, Huang W, Yu L, Yue W, Wang Z, Li P, Zhang Y, Liang R, Wei Z, Cui Y, Xie W, Cai M, Yu X, Yuan Y, Xia X, Zhang X, Yang H, Qiu W, Yang J, Gong F, Chen M, Shen H, Lin D, Zeng YX, He F, Zhou G.

Nat Genet. 2010 Sep;42(9):755-8. doi: 10.1038/ng.638. Epub 2010 Aug 1.


6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.

Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J.

Nat Cell Biol. 2015 Nov;17(11):1484-96. doi: 10.1038/ncb3255. Epub 2015 Oct 19. Review.


Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.

Shan C, Elf S, Ji Q, Kang HB, Zhou L, Hitosugi T, Jin L, Lin R, Zhang L, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J.

Mol Cell. 2014 Aug 21;55(4):552-65. doi: 10.1016/j.molcel.2014.06.020. Epub 2014 Jul 17.


Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.

Martins-de-Souza D, Guest PC, Mann DM, Roeber S, Rahmoune H, Bauder C, Kretzschmar H, Volk B, Baborie A, Bahn S.

J Proteome Res. 2012 Apr 6;11(4):2533-43. doi: 10.1021/pr2012279. Epub 2012 Mar 14.


Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

Zhao C, Denison C, Huibregtse JM, Gygi S, Krug RM.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10200-5. Epub 2005 Jul 11.


A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.

Herr P, Lundin C, Evers B, Ebner D, Bauerschmidt C, Kingham G, Palmai-Pallag T, Mortusewicz O, Frings O, Sonnhammer E, Helleday T.

Cell Discov. 2015 Dec 1;1:15034. doi: 10.1038/celldisc.2015.34. eCollection 2015.

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