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Items: 1 to 20 of 130

1.

Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase.

Baumann F, Bauer MS, Rees M, Alexandrovich A, Gautel M, Pippig DA, Gaub HE.

Elife. 2017 Jul 11;6. pii: e26473. doi: 10.7554/eLife.26473.

2.

Loss-of-Function Variants in MYLK Cause Recessive Megacystis Microcolon Intestinal Hypoperistalsis Syndrome.

Halim D, Brosens E, Muller F, Wangler MF, Beaudet AL, Lupski JR, Akdemir ZHC, Doukas M, Stoop HJ, de Graaf BM, Brouwer RWW, van Ijcken WFJ, Oury JF, Rosenblatt J, Burns AJ, Tibboel D, Hofstra RMW, Alves MM.

Am J Hum Genet. 2017 Jul 6;101(1):123-129. doi: 10.1016/j.ajhg.2017.05.011. Epub 2017 Jun 8.

3.

Myosin Light Chain Kinase MYLK1: Anatomy, Interactions, Functions, and Regulation.

Khapchaev AY, Shirinsky VP.

Biochemistry (Mosc). 2016 Dec;81(13):1676-1697. doi: 10.1134/S000629791613006X. Review.

4.

A novel variant in MYLK causes thoracic aortic dissections: genotypic and phenotypic description.

Hannuksela M, Stattin EL, Klar J, Ameur A, Johansson B, Sörensen K, Carlberg B.

BMC Med Genet. 2016 Sep 1;17(1):61. doi: 10.1186/s12881-016-0326-y.

5.

Epigenetic contribution of the myosin light chain kinase gene to the risk for acute respiratory distress syndrome.

Szilágyi KL, Liu C, Zhang X, Wang T, Fortman JD, Zhang W, Garcia JGN.

Transl Res. 2017 Feb;180:12-21. doi: 10.1016/j.trsl.2016.07.020. Epub 2016 Aug 1.

6.

Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene.

Mascarenhas JB, Tchourbanov AY, Fan H, Danilov SM, Wang T, Garcia JG.

Am J Respir Cell Mol Biol. 2017 Jan;56(1):29-37. doi: 10.1165/rcmb.2016-0053OC.

7.

Myosin Light Chain Kinase (MLCK) Gene Influences Exercise Induced Muscle Damage during a Competitive Marathon.

Del Coso J, Valero M, Lara B, Salinero JJ, Gallo-Salazar C, Areces F.

PLoS One. 2016 Aug 2;11(8):e0160053. doi: 10.1371/journal.pone.0160053. eCollection 2016. Erratum in: PLoS One. 2016 Dec 9;11(12 ):e0168309.

8.

Highly sensitive myosin phosphorylation analysis in the renal afferent arteriole.

Takeya K.

J Smooth Muscle Res. 2016;52(0):45-55. doi: 10.1540/jsmr.52.45. Review.

9.

Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling.

Kim DY, Helfman DM.

Oncogene. 2016 Aug 25;35(34):4495-508. doi: 10.1038/onc.2015.508. Epub 2016 Feb 15.

PMID:
26876209
10.

Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability in vitro and in vivo.

Wu F, Guo X, Xu J, Wang W, Li B, Huang Q, Su L, Xu Q.

Diab Vasc Dis Res. 2016 Mar;13(2):137-44. doi: 10.1177/1479164115610469. Epub 2015 Nov 24.

PMID:
26607798
11.

Structure-Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants.

Shen K, Ramirez B, Mapes B, Shen GR, Gokhale V, Brown ME, Santarsiero B, Ishii Y, Dudek SM, Wang T, Garcia JG.

PLoS One. 2015 Jun 25;10(6):e0130515. doi: 10.1371/journal.pone.0130515. eCollection 2015.

12.

Fine mapping of the myosin light chain kinase (MYLK) gene replicates the association with asthma in populations of Spanish descent.

Acosta-Herrera M, Pino-Yanes M, Ma SF, Barreto-Luis A, Corrales A, Cumplido J, Pérez-Rodríguez E, Campo P, Eng C, García-Robaina JC, Quintela I, Villar J, Blanca M, Carracedo Á, Carrillo T, Garcia JG, Torgerson DG, Burchard EG, Flores C.

J Allergy Clin Immunol. 2015 Oct;136(4):1116-8.e9. doi: 10.1016/j.jaci.2015.04.025. Epub 2015 May 27. No abstract available.

13.

Performant Mutation Identification Using Targeted Next-Generation Sequencing of 14 Thoracic Aortic Aneurysm Genes.

Proost D, Vandeweyer G, Meester JA, Salemink S, Kempers M, Ingram C, Peeters N, Saenen J, Vrints C, Lacro RV, Roden D, Wuyts W, Dietz HC, Mortier G, Loeys BL, Van Laer L.

Hum Mutat. 2015 Aug;36(8):808-14. doi: 10.1002/humu.22802. Epub 2015 Jun 13.

PMID:
25907466
14.

Serum myosin light chain kinase in type 2 diabetes mellitus: a cross-sectional study.

Di Y, Pan W, Li X.

Ann Clin Lab Sci. 2015 Winter;45(1):54-7.

PMID:
25696011
15.

Melatonin protects the esophageal epithelial barrier by suppressing the transcription, expression and activity of myosin light chain kinase through ERK1/2 signal transduction.

Tan J, Wang Y, Xia Y, Zhang N, Sun X, Yu T, Lin L.

Cell Physiol Biochem. 2014;34(6):2117-27. doi: 10.1159/000369656. Epub 2014 Nov 28.

16.

Regulation of calcium channels in smooth muscle: new insights into the role of myosin light chain kinase.

Martinsen A, Dessy C, Morel N.

Channels (Austin). 2014;8(5):402-13. doi: 10.4161/19336950.2014.950537. Review.

17.

A MYLK variant regulates asthmatic inflammation via alterations in mRNA secondary structure.

Wang T, Zhou T, Saadat L, Garcia JG.

Eur J Hum Genet. 2015 Jun;23(6):874-6. doi: 10.1038/ejhg.2014.201. Epub 2014 Oct 1.

18.

IgE regulates the expression of smMLCK in human airway smooth muscle cells.

Balhara J, Redhu NS, Shan L, Gounni AS.

PLoS One. 2014 Apr 10;9(4):e93946. doi: 10.1371/journal.pone.0093946. eCollection 2014.

19.

MicroRNA regulation of nonmuscle myosin light chain kinase expression in human lung endothelium.

Adyshev DM, Moldobaeva N, Mapes B, Elangovan V, Garcia JG.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):58-66. doi: 10.1165/rcmb.2012-0397OC.

20.

Myosin-activating protein kinases are possible regulators of nonmuscle myosin in developing human heart.

Stepanova OV, Chadin AV, Masyutin AG, Kulikova TG, Poltavceva RA, Masenko VP, Sukhikh GT.

Bull Exp Biol Med. 2011 Dec;152(2):198-201. English, Russian.

PMID:
22808459

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