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Items: 1 to 20 of 871

1.

Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.

Balboa D, Saarimäki-Vire J, Borshagovski D, Survila M, Lindholm P, Galli E, Eurola S, Ustinov J, Grym H, Huopio H, Partanen J, Wartiovaara K, Otonkoski T.

Elife. 2018 Nov 9;7. pii: e38519. doi: 10.7554/eLife.38519.

2.

C-Peptide and cardiovascular risk factors among young adults in a southern Brazilian cohort.

Andrade RLM, Gigante DP, de Oliveira IO, Horta BL.

BMC Endocr Disord. 2018 Nov 6;18(1):80. doi: 10.1186/s12902-018-0308-5.

3.

Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium.

Lee Y, Chakraborty S, Meininger CJ, Muthuchamy M.

Microcirculation. 2018 Oct;25(7):e12492. doi: 10.1111/micc.12492. Epub 2018 Aug 27.

PMID:
30025187
4.

Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response.

Xin Y, Dominguez Gutierrez G, Okamoto H, Kim J, Lee AH, Adler C, Ni M, Yancopoulos GD, Murphy AJ, Gromada J.

Diabetes. 2018 Sep;67(9):1783-1794. doi: 10.2337/db18-0365. Epub 2018 Jun 27.

5.

Circulating Sphingolipids, Insulin, HOMA-IR, and HOMA-B: The Strong Heart Family Study.

Lemaitre RN, Yu C, Hoofnagle A, Hari N, Jensen PN, Fretts AM, Umans JG, Howard BV, Sitlani CM, Siscovick DS, King IB, Sotoodehnia N, McKnight B.

Diabetes. 2018 Aug;67(8):1663-1672. doi: 10.2337/db17-1449. Epub 2018 Mar 27.

6.

Effect of glycated insulin on the blood-brain barrier permeability: An in vitro study.

Shahriyary L, Riazi G, Lornejad MR, Ghezlou M, Bigdeli B, Delavari B, Mamashli F, Abbasi S, Davoodi J, Saboury AA.

Arch Biochem Biophys. 2018 Jun 1;647:54-66. doi: 10.1016/j.abb.2018.02.004. Epub 2018 Feb 11.

PMID:
29444458
7.

Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins.

Guo H, Sun J, Li X, Xiong Y, Wang H, Shu H, Zhu R, Liu Q, Huang Y, Madley R, Wang Y, Cui J, Arvan P, Liu M.

J Biol Chem. 2018 Feb 9;293(6):1899-1907. doi: 10.1074/jbc.RA117.000922. Epub 2017 Dec 11.

8.

Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion.

Fine NHF, Doig CL, Elhassan YS, Vierra NC, Marchetti P, Bugliani M, Nano R, Piemonti L, Rutter GA, Jacobson DA, Lavery GG, Hodson DJ.

Diabetes. 2018 Feb;67(2):278-290. doi: 10.2337/db16-1356. Epub 2017 Dec 4.

9.

Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease.

Geijselaers SLC, Aalten P, Ramakers IHGB, De Deyn PP, Heijboer AC, Koek HL, OldeRikkert MGM, Papma JM, Reesink FE, Smits LL, Stehouwer CDA, Teunissen CE, Verhey FRJ, van der Flier WM, Biessels GJ; Parelsnoer Institute Neurodegenerative Diseases study group.

J Alzheimers Dis. 2018;61(1):309-320. doi: 10.3233/JAD-170522.

10.

Relation of Muscle Indices with Metabolic Parameters and C-Peptide in Type 2 Diabetes Mellitus.

Tuzun S, Oner C, Dabak MR, Kasikci HO, Sargin M.

J Coll Physicians Surg Pak. 2017 Nov;27(11):673-677. doi: 2740.

PMID:
29132475
11.

Human pancreatic islet-derived extracellular vesicles modulate insulin expression in 3D-differentiating iPSC clusters.

Ribeiro D, Andersson EM, Heath N, Persson-Kry A, Collins R, Hicks R, Dekker N, Forslöw A.

PLoS One. 2017 Nov 8;12(11):e0187665. doi: 10.1371/journal.pone.0187665. eCollection 2017.

12.

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation.

Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, Gertow K, Giral P, Goel A, Humphries SE, Kurl S, Langenberg C, Lannfelt LL, Lind L, Lindgren CCM, Mannarino E, Mook-Kanamori DO, Morris AP, de Mutsert R, Rauramaa R, Saliba-Gustafsson P, Sennblad B, Smit AJ, Syvänen AC, Tremoli E, Veglia F, Zethelius B, Björck HM, Eriksson JG, Hofman A, Franco OH, Watkins H, Jukema JW, Florez JC, Wareham NJ, Meigs JB, Ingelsson E, Baldassarre D, Hamsten A; IMPROVE study group.

Atherosclerosis. 2017 Nov;266:196-204. doi: 10.1016/j.atherosclerosis.2017.09.031. Epub 2017 Sep 28.

13.

C-peptide levels and the risk of diabetes and pre-diabetes among Chinese women with gestational diabetes.

Yin P, Shao P, Liu H, Li W, Wang L, Wang J, Zhang S, Leng J, Li N, Tian H, Yang X, Yu Z, Hu G.

J Diabetes Complications. 2017 Dec;31(12):1658-1662. doi: 10.1016/j.jdiacomp.2017.08.006. Epub 2017 Aug 17.

14.

A 4D view on insulin secretory granule turnover in the β-cell.

Müller A, Mziaut H, Neukam M, Knoch KP, Solimena M.

Diabetes Obes Metab. 2017 Sep;19 Suppl 1:107-114. doi: 10.1111/dom.13015. Review.

PMID:
28880479
15.

Role of G-proteins in islet function in health and diabetes.

Kowluru A.

Diabetes Obes Metab. 2017 Sep;19 Suppl 1:63-75. doi: 10.1111/dom.13011. Review.

16.

Recent new insights into the role of SNARE and associated proteins in insulin granule exocytosis.

Gaisano HY.

Diabetes Obes Metab. 2017 Sep;19 Suppl 1:115-123. doi: 10.1111/dom.13001. Review.

PMID:
28880475
17.

Role of the glucose-sensing receptor in insulin secretion.

Kojima I, Medina J, Nakagawa Y.

Diabetes Obes Metab. 2017 Sep;19 Suppl 1:54-62. doi: 10.1111/dom.13013. Review.

PMID:
28880472
18.

Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.

Wasserfall C, Nick HS, Campbell-Thompson M, Beachy D, Haataja L, Kusmartseva I, Posgai A, Beery M, Rhodes C, Bonifacio E, Arvan P, Atkinson M.

Cell Metab. 2017 Sep 5;26(3):568-575.e3. doi: 10.1016/j.cmet.2017.08.013.

19.

Proinsulin Promotes Self-Renewal of a Hematopoietic Progenitor Cell Line In Vitro.

Han Y, Liu T, Zou Y, Ji L, Li Y, Li J, Wang J, Chen G, Chen J, Chen L, Ye Z.

J Diabetes Res. 2017;2017:5649191. doi: 10.1155/2017/5649191. Epub 2017 Jul 3.

20.

Conditions of gestation, childbirth and childhood associated with C-peptide in young adults in the 1982 Birth Cohort in Pelotas-RS; Brazil.

Andrade RLM, Gigante DP, de Oliveira IO, Horta BL.

BMC Cardiovasc Disord. 2017 Jul 11;17(1):181. doi: 10.1186/s12872-017-0613-3.

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