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Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease.

McLeod O, Silveira A, Valdes-Marquez E, Björkbacka H, Almgren P, Gertow K, Gådin JR, Bäcklund A, Sennblad B, Baldassarre D, Veglia F, Humphries SE, Tremoli E, de Faire U, Nilsson J, Melander O, Hopewell JC, Clarke R, Björck HM, Hamsten A, Öhrvik J, Strawbridge RJ; IMPROVE Study Group.

Cytokine. 2016 May;81:1-9. doi: 10.1016/j.cyto.2016.01.007. Epub 2016 Jan 25.


IL-5, IL-8 and MMP -9 levels in exhaled breath condensate of atopic and nonatopic asthmatic children.

Turkeli A, Yilmaz O, Taneli F, Horasan GD, Kanik ET, Kizilkaya M, Gozukara C, Yuksel H.

Respir Med. 2015 Jun;109(6):680-8. doi: 10.1016/j.rmed.2015.04.004. Epub 2015 Apr 15.


IL-5 production by resident mucosal allergen-specific T cells in an explant model of allergic rhinitis.

Skrindo I, Ballke C, Gran E, Johansen FE, Baekkevold ES, Jahnsen FL.

Clin Exp Allergy. 2015 Aug;45(8):1296-304. doi: 10.1111/cea.12543.


Plasma IL-5 concentration and subclinical carotid atherosclerosis.

Silveira A, McLeod O, Strawbridge RJ, Gertow K, Sennblad B, Baldassarre D, Veglia F, Deleskog A, Persson J, Leander K, Gigante B, Kauhanen J, Rauramaa R, Smit AJ, Mannarino E, Giral P, Gustafsson S, Söderberg S, Öhrvik J, Humphries SE, Tremoli E, de Faire U, Hamsten A.

Atherosclerosis. 2015 Mar;239(1):125-30. doi: 10.1016/j.atherosclerosis.2014.12.046. Epub 2014 Dec 23.


Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils.

Burnham ME, Esnault S, Roti Roti EC, Bates ME, Bertics PJ, Denlinger LC.

PLoS One. 2014 Aug 14;9(8):e103122. doi: 10.1371/journal.pone.0103122. eCollection 2014.


Allergen-specific IL-5 responses in early childhood predict asthma at age eight.

Weber-Chrysochoou C, Crisafulli D, Kemp AS, Britton WJ, Marks GB; CAPS Investigators.

PLoS One. 2014 May 29;9(5):e97995. doi: 10.1371/journal.pone.0097995. eCollection 2014.


Mechanisms of human eosinophil migration induced by the combination of IL-5 and the endocannabinoid 2-arachidonoyl-glycerol.

Larose MC, Turcotte C, Chouinard F, Ferland C, Martin C, Provost V, Laviolette M, Flamand N.

J Allergy Clin Immunol. 2014 May;133(5):1480-2, 1482.e1-3. doi: 10.1016/j.jaci.2013.12.1081. Epub 2014 Feb 13. No abstract available.


Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Grey HM, Sette A, Peters B.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3459-64. doi: 10.1073/pnas.1300512110. Epub 2013 Feb 11. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269. Ferreira-Briza, Fatima [corrected to Ferreira, Fatima]. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8750.


Inhibition of interleukin-5 for the treatment of eosinophilic diseases.

Corren J.

Discov Med. 2012 Apr;13(71):305-12. Review.


Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor.

Molfino NA, Gossage D, Kolbeck R, Parker JM, Geba GP.

Clin Exp Allergy. 2012 May;42(5):712-37. doi: 10.1111/j.1365-2222.2011.03854.x. Epub 2011 Sep 23. Review.


Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cells.

Upadhyaya B, Yin Y, Hill BJ, Douek DC, Prussin C.

J Immunol. 2011 Sep 15;187(6):3111-20. doi: 10.4049/jimmunol.1101283. Epub 2011 Aug 17.


[Eosinophilic infiltration of lung cancer tissue and its correlation with the expression of interleukin-5].

Han X, Zhang P, Wang J, He B.

Zhonghua Yi Xue Za Zhi. 2011 Apr 12;91(14):956-60. Chinese.


Early induction of interleukin-5 and peripheral eosinophilia in acute pneumonia in Japanese children infected by pandemic 2009 influenza A in the Tokyo area.

Terai M, Honda T, Yamamoto S, Yoshida M, Tsuchiya N, Moriyama Y, Matsui T, Tokutake S, Suzuki E, Shirato Y, Muto A, Hayashi K, Hamada H.

Microbiol Immunol. 2011 May;55(5):341-6. doi: 10.1111/j.1348-0421.2011.00320.x.


In vitro levels of cytokines in response to purified protein derivative (PPD) antigen in a population with high prevalence of pulmonary tuberculosis.

Giampietro F, de Waard JH, Rivas-Santiago B, Enciso-Moreno JA, Salgado A, Araujo Z.

Hum Immunol. 2010 Nov;71(11):1099-104. doi: 10.1016/j.humimm.2010.07.006. Epub 2010 Aug 2.


A role for interleukin-5 in promoting increased immunoglobulin M at the site of disease in leprosy.

Ochoa MT, Teles R, Haas BE, Zaghi D, Li H, Sarno EN, Rea TH, Modlin RL, Lee DJ.

Immunology. 2010 Nov;131(3):405-14. doi: 10.1111/j.1365-2567.2010.03314.x.


Common genetic variants and risk for non-Hodgkin lymphoma and adult T-cell lymphoma/leukemia in Jamaica.

Wang SS, Carreon JD, Hanchard B, Chanock S, Hisada M.

Int J Cancer. 2009 Sep 15;125(6):1479-82. doi: 10.1002/ijc.24489.


Sputum IL-5 concentration is associated with a sputum eosinophilia and attenuated by corticosteroid therapy in COPD.

Bafadhel M, Saha S, Siva R, McCormick M, Monteiro W, Rugman P, Dodson P, Pavord ID, Newbold P, Brightling CE.

Respiration. 2009;78(3):256-62. doi: 10.1159/000221902. Epub 2009 May 27.


Prognostic significance of B-cell differentiation genes encoding proteins in diffuse large B-cell lymphoma and follicular lymphoma grade 3.

Borovecki A, Korać P, Nola M, Ivanković D, Jaksić B, Dominis M.

Croat Med J. 2008 Oct;49(5):625-35.


Reduced interleukin-5 production by peripheral CD4+ T cells in common variable immunodeficiency patients.

Del Vecchio GC, Martire B, Lassandro G, Cecinati V, De Mattia D, Ciccarelli M, Piacente L, Giordano P.

Immunopharmacol Immunotoxicol. 2008;30(4):679-86. doi: 10.1080/08923970802278102 .


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